A5100670697- Ecology and Conservation Studies
- Greenhouse Technology and Climate Control
- Plant Physiology and Cultivation Studies
- Agriculture, Soil, Plant Science
- Diverse Approaches in Healthcare and Education Studies
- Plant and animal studies
- Flowering Plant Growth and Cultivation
- Fire effects on ecosystems
- Genomics, phytochemicals, and oxidative stress
- Advances in Cucurbitaceae Research
- TGF-β signaling in diseases
- Insect and Pesticide Research
- Entomopathogenic Microorganisms in Pest Control
- Plant Disease Resistance and Genetics
- Bone Metabolism and Diseases
- Insect and Arachnid Ecology and Behavior
- Plant Growth and Agriculture Techniques
- Inflammasome and immune disorders
- Postharvest Quality and Shelf Life Management
- Immune Response and Inflammation
- COVID-19 Clinical Research Studies
- Tryptophan and brain disorders
- Inflammatory mediators and NSAID effects
- Fungal Biology and Applications
- Cancer-related gene regulation
University of Southern California
2017-2024
Southern California University for Professional Studies
2024
National Institute of Agricultural Science and Technology
2022-2023
Pusan National University
2020-2022
Advanced Institute of Convergence Technology
2017-2021
Seoul National University
2008-2021
Dongguk University
2018
Zero to Three
2016
Osaka University
2005-2008
Osaka International University
2005-2008
Abstract Although tetraarsenic hexoxide is known to exert an anti-tumor effect by inducing apoptosis in various cancer cells, its on other forms of regulated cell death remains unclear. Here, we show that induces the pyroptotic through activation mitochondrial reactive oxygen species (ROS)-mediated caspase-3/gasdermin E (GSDME) pathway, thereby suppressing tumor growth and metastasis triple-negative breast (TNBC) cells. Interestingly, hexoxide-treated TNBC cells exhibited specific...
Scope Brain‐derived neurotrophic factor (BDNF) is a neurotrophin that supports the survival of existing neurons and encourages growth differentiation new synapses. We investigated effect sulforaphane, hydrolysis product glucoraphanin present in Brassica vegetables, on neuronal BDNF expression its synaptic signaling pathways. Methods results Mouse primary cortical triple‐transgenic mouse model Alzheimer's disease (3 × Tg‐AD) were used to study sulforaphane. Sulforaphane enhanced increased...
Scope Sulforaphane is an herbal isothiocyanate enriched in cruciferous vegetables. Here, the authors investigate whether sulforaphane modulates production of amyloid‐β (Aβ) and tau, two main pathological factors Alzheimer's disease (AD). Methods results A triple transgenic mouse model AD (3 × Tg‐AD) used to study effect sulforaphane. Oral gavage reduces protein levels monomeric polymeric forms Aβ as well tau phosphorylated 3 Tg‐AD mice. However, treatment do not affect mRNA expression...
Abstract The transient receptor potential vanilloid 1 (TRPV1) protein is a pain that elicits hot sensation when an organism eats the capsaicin of red chili peppers. This calcium (Ca2+)-permeable cation channel mostly expressed in peripheral nervous system sensory neurons but also central (e.g. hippocampus and cortex). Preclinical studies found TRPV1 mediates behaviors associated with anxiety depression. Loss functionality increases expression genes related to synaptic plasticity...
Ginseng (Panax ginseng C.A. Meyer) has been used as a traditional herb in the treatment of many medical disorders. Ginsenosides, which are triterpene derivatives that contain sugar moieties, main pharmacological ingredients ginseng. This study was designed to investigate effect ginsenoside Rg3-enriched extract (Rg3GE) on scopolamine-induced memory impairment mice. Rg3GE (50 and 100 mg/kg) were administered C57BL/6 mice by oral gavage for 14 days (days 1–14). Memory induced scopolamine (1...
Osteoarthritis is the most common form of arthritis, and pain relief with opioid-like drugs a commonly used therapeutic for osteoarthritic patients. Recent studies published by our group showed that kappa opioid receptor (KOR) highly expressed during human development in joint-forming cells. However, precise role this skeletal system remains elusive. The main aim current study was to investigate KOR signaling synovial cartilaginous tissues pathological conditions. Our data demonstrate null...
Inhibition of hedgehog (HH) signaling prevents cartilage degeneration and promotes repair in animal models osteoarthritis (OA). This study, undertaken OA human articular cartilage, was designed to explore whether kappa opioid receptor (KOR) modulation via the inhibition HH may have therapeutic potential for achieving disease-modifying activity OA.Primary synovial tissue samples from patients with knee undergoing total joint replacement healthy subjects were obtained National Disease Research...
Watermelon fruit rind color (RC) and bloom formation (BF) affect product value consumer preference. However, information on the candidate gene(s) for additional loci involved in dark green (DG) RC genetic control of BF its major chemical components is lacking. Therefore, this study aimed to identify controlling using QTL-seq F2 population derived by crossing 'FD061129' with light-green 'SIT55616RN' DG bloomless. Phenotypic evaluation F1 219 plants indicated two complementary dominant loci,...
농업생태계는 본래 가졌던 식량생산 이외에도 수질정화, 생물서식처, 대기정화, 토양보전, 경관창출 등 다양한 서비스를 제공하는 공간으로 평가 받는다. 농업경관에서 시설원예단지 조성은 불투수면적 확장과 생물서식처 손실로 인해 생태계서비스 기능저하의 원인이 될 수 있다고 평가된다. 따라서 본 연구는 시설원예단지가 조성 된 상태와 논생태계의 곤충다양성을 비교하고자 하였다. 연구대상지는 분포현황을 고려해 단동형온실, 연동형온실, 유리온실로 구분하고, 논 4개소와 비교하였다. 조사 지역은 구미, 부여, 진주, 김제 등으로 선정하였다. 조사에서 채집된 종은 9목 38과 76속 80종으로 총 2333개체가 채집되었다. 목 노린재목 22.37%, 딱정벌레목 18.42%, 벌목 14.47%, 메뚜기목 11.84%, 파리목 10.53%, 나비목 10.53% 구분된다. 채집 종의 평균은 논(39.4종)> 단동형온실(35.5종)> 연동형온실(22.5종)> 유리온실(24.0종)의 순이다....
Despite the use of vaccines and therapeutics against coronavirus disease 2019 (COVID-19) pandemic, this severe has been a critical burden on public health, whereas pathogenic mechanism remains elusive. Recently, accumulating evidence underscores potential role aberrant B-cell response humoral immunity in progression, especially high-risk groups. Using single-cell RNA (scRNA) sequencing analysis, we investigated transcriptional features population peripheral blood from COVID-19 patients...
Sujin Park, Kyung-Min Yang, Yuna Eunji Hong, Chang Pyo Jinah Kyoungwha Pang, Jihee Lee, Bora Siyoung Haein An, Mi-Kyung Kwak, Junil Kim, Jin Muk Kang, Pyunggang Yang Xiao, Guangjun Nie, Akira Ooshima, and Seong-Jin Kim. Journal of Cancer Prevention 2018;23:1-9. https://doi.org/10.15430/JCP.2018.23.1.1
Honeybees pollinate over 75% of the total food resources produced annually, and they produce valuable hive products, such as bee pollen, propolis, royal jelly. However, species Asian hornet (Vespa velutina) feed on more than 85% honeybees, causing a decline in their population considerable damage to beekeepers Korea. To prevent portable real-time monitoring system was developed that detects V. velutina individuals notifies users presence. This designed with focus portability ease...
Trans-lycopene is a functional phytochemical abundant in red-fleshed watermelons, and its contents vary among cultivars. In this study, the genetic basis of high trans-lycopene scarlet red flesh was evaluated. Three near-isogenic lines (NILs) with were derived from donor parent DRD three coral (low contents) recurrent parents. The lycopene (589.4 ± 71.8 µg/g) two times higher than that parents, values for NILs intermediate between those Coral F1 cultivars showed low (135.7 18.0 µg/g to 213.7...
Food craving is one of the fundamental desires human nature. Many HCI researchers used to define this desire as a problem and has developed its corrective technology. However, positive aspects food reward rarely been in scope research. Few studies made efforts evaluate how positively interacts with mental humans but have shown inconsistent results because user subjectivity environmental variations. Therefore, we evaluated human-food interactions an EEG objective indicator track activity. We...