A5031327362- Cutaneous lymphoproliferative disorders research
- Fungal Infections and Studies
- Lymphoma Diagnosis and Treatment
- Nail Diseases and Treatments
- T-cell and Retrovirus Studies
- Autoimmune Bullous Skin Diseases
- Dermatology and Skin Diseases
- Cutaneous Melanoma Detection and Management
- Respiratory viral infections research
- Chemotherapy-related skin toxicity
- Cytokine Signaling Pathways and Interactions
- Phytochemical compounds biological activities
- Dermatological and Skeletal Disorders
- Pesticide Residue Analysis and Safety
- Genetic and rare skin diseases.
- IL-33, ST2, and ILC Pathways
- Histiocytic Disorders and Treatments
- Connective tissue disorders research
- Neonatal Respiratory Health Research
- Polyomavirus and related diseases
- Acne and Rosacea Treatments and Effects
- Methemoglobinemia and Tumor Lysis Syndrome
- Biochemical Analysis and Sensing Techniques
- Inflammatory Myopathies and Dermatomyositis
- Histone Deacetylase Inhibitors Research
Gdańsk Medical University
2016-2025
University Clinical Centre
2024
The Maria Sklodowska-Curie National Research Institute of Oncology
2023
Medical University of Lodz
2023
The University of Texas Medical Branch at Galveston
1997
The presence of histamine and eosinophil cationic protein in nasopharyngeal secretions infants with respiratory syncytial virus (RSV)-induced bronchiolitis implies the activation basophil leukocytes, but specific mechanism their recruitment has not been elucidated. Chemokines are potent selective leukocyte chemotactic molecules that also expressed by airway epithelial cells. Therefore, pattern chemokines produced response to RSV infection was investigated primary cultures human nose-...
Cutaneous T-cell lymphomas (CTCL) are a group of rare hematological malignancies characterized by infiltration malignant T-cells into the skin. Two main types CTCL constitute Mycosis Fungoides (MF), more indolent form disease, and Sézary syndrome (SS), aggressive leukemic variant with blood involvement. presents significant clinical challenge due to its very nature, poor prognosis, treatment resistance, date, disease remains incurable. Histone deacetylase inhibitors have gained attention in...
The skin barrier defect in cutaneous T-cell lymphomas (CTCL) was recently confirmed to be similar the one observed atopic dermatitis (AD). We have examined expression level of cornified envelope (CE) proteins CTCL, AD and healthy skin, search for differences their relation courses both diseases. levels FLG, FLG2, RPTN, HRNR, SPRR1A, SPRR1B, SPRR3 LELP-1 mRNA were determined by qRT-PCR, while protein using ELISA method samples. found that LOR, CRNN SPRR3v1 decreased (p ≤ 0.04), whereas HRNR...
The first report concerning methotrexate (MTX) in the treatment of Mycosis fungoides (MF) was published 1964 by Wright. mechanism MTX action primary cutaneous T-cell lymphoma (CTCL) has been not explained detail yet (the anti-inflammatory, immunomodulating, immunosuppressive, and cytostatic actions have under discussion).This is a retrospective analysis 79 MF patients 4 dermatology clinical centers Poland. Data are presented terms duration, use MTX, effectiveness with time required to...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Nedoszytko B, Olszewska Roszkiewicz J, et al. The role of polymorphism interleukin 2, 10, 13 and TNF-α genes in cutaneous T-cell lymphoma pathogenesis. Advances Dermatology Allergology/Postępy Dermatologii i Alergologii. 2016;33(6):429-434. doi:10.5114/ada.2016.63881. APA Nedoszytko, B., Olszewska, Roszkiewicz, J., Glen, Zabłotna, M., & Ługowska-Umer, H. (2016). Alergologii, 33(6), 429-434....
IL-6/STAT3 signaling pathway has been suggested to play a role in CTCL pathogenesis. Polymorphisms STAT3 pathway-related genes might be risk factor for CTCL. However, the exact of inherited gene polymorphisms IL-6 and pathogenesis is still not fully understood. The aim was examine whether cytokine are associated with susceptibility, stage disease pruritus intensity. We compared serum level frequency selected single nucleotide 106 198 control group using polymerase chain reaction...
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Vitiligo is an acquired chronic depigmenting disorder of the skin, predominantly asymptomatic. Although vitiligo does not cause direct physical impairment, it commonly believed that can produce important psychosocial burden.To translate, cross-culturally adapt and validate vitiligo-specific health-related quality life instrument (VitiQoL) into Polish.The study was conducted online on 97 patients with from our private outpatient departments in Gdynia Gdansk, Poland May 2018 to December...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Sokołowska-Wojdyło M, Kłudkowska J, Olszewska B, et al. The first case of drug-induced pseudoscleroderma and eczema craquelé related to nab-paclitaxel pancreatic adenocarcinoma treatment. Advances in Dermatology Allergology/Postępy Dermatologii i Alergologii. 2018;35(1):106-108. doi:10.5114/pdia.2017.67054. APA Sokołowska-Wojdyło, M., Kłudkowska, J., Olszewska, B., Seredyńska, Biernat, W., & Błażewicz, I....
Cutaneous T-cell lymphomas (CTCL) are malignant lymphoproliferative disorders accompanied by persistent pruritus. Pruritogenic role of interleukin-31 (IL-31) has been studied extensively and was proven in atopic dermatitis (AD), while its CTCL is still rather vague. To investigate IL-31 serum level along with IL-31, receptor α (IL-31RA) oncostatin M β (OSMR) skin expression compare it to controls: AD healthy volunteers. The measured using ELISA, receptors' the were immunohistochemistry...
Tumour microenvironment has an important effect on the progression of cutaneous T-cell lymphomas. Using PCR with sequence-specific primers, this study analysed single-nucleotide polymorphisms in interleukin-17 genes 150 patients lymphoma. GG homozygote rs8193036 A/G interleukin-17A gene occurred less commonly lymphoma group; however, polymorphism experience significantly intense pruritus. Conversely, rs2397084 AG heterozygote interleukin-17F is more common population. In addition, there were...
Abstract Background Deregulation of signal transducer and activator transcription (STAT) signaling is known to participate in the pathogenesis cutaneous T‐cell lymphomas (CTCLs). However, published results regarding STAT expression different stages CTCLs are conflicting. The aim study was define pattern skin detect any differences between pruritic nonpruritic patients but also disease. Methods Thirty‐nine biopsies from CTCL 24 healthy volunteers were taken. Immunohistochemical staining for...
Cutaneous T-cell lymphomas (CTCLs) are a diverse group of non-Hodgkin's with malignant T lymphocytes infiltrating the skin. Mycosis fungoides (MF) and Sézary syndrome (SS) belong to CTCLs, among others. In previous studies it was suggested that primary cancers more often occur in patients cutaneous lymphoma.To analyse incidence other malignancies CTCL patients.The evaluation coexistence neoplasms conducted by analysis patients' database, diagnosis mycosis syndrome, treated Dermatological...
AMA Sokołowska-Wojdyło M, Olszewska B, Chmielowska E, et al. Primary cutaneous lymphomas. Diagnostic and therapeutic guidelines of the Polish Dermatological Society (PTD) Lymphoma Research Group (PLRG). Dermatology Review/Przegląd Dermatologiczny. 2023;110(6):647-674. doi:10.5114/dr.2023.138937. APA Sokołowska-Wojdyło, M., Olszewska, B., Chmielowska, E., Robak, Prochorec-Sobieszek, & Kamińska-Winciorek, G. (2023). Dermatologiczny, 110(6), 647-674. https://doi.org/10.5114/dr.2023.138937...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Błażewicz I, Sokołowska-Wojdyło M, Piekarska A, et al. Langerhans cell histiocytosis followed by folliculotropic mycosis fungoides. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2017;34(3):273-275. doi:10.5114/pdia.2017.67055. APA Błażewicz, I., Sokołowska-Wojdyło, M., Piekarska, A., Sadowska-Klasa, Kowalczyk, & Konczalska, M. (2017). Alergologii, 34(3), 273-275....
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Olszewska B, Imko-Walczuk Nowicki R, Dębska-Ślizień A, Wilkowska Rutkowski B. Superficial and deep cutaneous fungal infections in solid organ transplant recipients. Dermatology Review/Przegląd Dermatologiczny. 2016;103(4):259-272. doi:10.5114/dr.2016.61773. APA Olszewska, B., Imko-Walczuk, Nowicki, R., Dębska-Ślizień, A., Wilkowska, & Rutkowski, (2016). Dermatologiczny, 103(4), 259-272....
ESMO guidelines recommend interferon (IFN) and methotrexate (MTX) as first-line systemic therapies in mycosis fungoides (MF) Sezary syndrome (SS).A prospective, head-to-head trial comparing the efficacy safety of INF-α MTX treatment MF/SS patients.Forty-three patients were enrolled trial. The response to side effects assessed. Study variables included mSWAT, DLQI, VAS scores.The rate stage IV including SS was significantly higher IFN-α group than (100% vs. 40%; p = 0.03, respectively). No...