A5100462734- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Respiratory Support and Mechanisms
- Liver Disease Diagnosis and Treatment
- Bacterial Infections and Vaccines
- Helicobacter pylori-related gastroenterology studies
- Airway Management and Intubation Techniques
- Tracheal and airway disorders
- COVID-19 Clinical Research Studies
- Pleural and Pulmonary Diseases
- Pneumonia and Respiratory Infections
- Infective Endocarditis Diagnosis and Management
- Liver Disease and Transplantation
- Intensive Care Unit Cognitive Disorders
- Biosensors and Analytical Detection
- Medical Imaging and Pathology Studies
- Tuberculosis Research and Epidemiology
- Neonatal Respiratory Health Research
- Gastric Cancer Management and Outcomes
- Cancer-related Molecular Pathways
- Eosinophilic Esophagitis
- Viral gastroenteritis research and epidemiology
- Dermatologic Treatments and Research
- Long-Term Effects of COVID-19
- Folate and B Vitamins Research
- Pneumothorax, Barotrauma, Emphysema
Ajou University
2017-2024
Korea University
2021-2023
Daegu Catholic University Medical Center
2017-2023
Catholic University of Daegu
2020-2023
University of Ulsan
2013-2023
Ulsan College
2013-2023
Asan Medical Center
2013-2023
Hanyang University
2012-2021
Meikai University
2021
Yonsei University
2014-2021
Pumpkins have considerable variation in nutrient contents depending on the cultivation environment, species, or part. In this study, general chemical compositions and some bioactive components, such as tocopherols, carotenoids, β-sitosterol, were analyzed three major species of pumpkin (Cucurbitaceae pepo, C. moschata, maxima) grown Korea also parts (peel, flesh, seed) each species. maxima had significantly more carbohydrate, protein, fat, fiber than pepo moschata (P < 0.05). The moisture...
To propose a modified angiographic classification for peripheral arteriovenous malformations (AVMs) and to determine its value assessing therapeutic outcomes approaches ethanol embolization of AVMs in the body extremities.AVMs trunk extremities were categorized according morphology nidus: type I (arteriovenous fistulae), II (arteriolovenous IIIa (arteriolovenulous fistulae with non-dilated fistula), IIIb dilated fistula). Sixty-six patients (41 women; mean age 28.3 years, range 5-53)...
Abstract Background The impact of sarcopenia on clinical outcomes coronavirus disease 2019 (COVID-19) is not clearly determined yet. We aimed to investigate the association between baseline and in patients with COVID-19. Methods All hospitalized adult COVID-19 who had chest computed tomography (CT) scans at a Korean university hospital from February 2020 May were included. main outcome was time admission discharge. Death considered as competing risk for Baseline skeletal muscle...
It has been reported that klotho deficiency is associated with oxidative stress and inflammation in experimental kidney disease models. Patients endstage renal (ESRD) are particularly characterized by increased inflammation. However, little known about the relationship between these features patients ESRD.We conducted a single-center, cross-sectional study of 78 receiving peritoneal dialysis (PD). Serum concentrations klotho, high-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6),...
Background Neisseria meningitidis (Nm) is a leading causative agent of bacterial meningitis in humans. Traditionally, meningococcal has been diagnosed by culture. However, isolation bacteria from patients' cerebrospinal fluid (CSF) time consuming and sometimes yields negative results. Recently, polymerase chain reaction (PCR)-based diagnostic methods detecting Nm have considered the gold standard because their superior sensitivity specificity compared with In this study, we developed...
The effect of intubation timing on the prognosis critically ill patients with coronavirus 2019 (COVID-19) is not yet well understood. We investigated whether early associated survival COVID-19 acute respiratory distress syndrome (ARDS). This multicenter, retrospective, observational study was done 47 adult ARDS who were admitted to intensive care unit (ICU) in Daegu, Korea between February 17 and April 23, 2020. Clinical characteristics in-hospital mortality compared initially non-intubated...
ABSTRACT Objective To determine if cervical cerclage reduces the rate of spontaneous early preterm birth in cases dichorionic–diamniotic (DCDA) twin gestation with an ultrasound‐detected short cervix. Methods This was a retrospective cohort study 40 consecutive DCDA gestations at Saint Peter's University Hospital from November 2006 to 2014 which performed for ultrasound‐determined length 1–24 mm 16–24 weeks' gestation. The were matched controls without and gestational age assessment. primary...
Rationale Establishing an interstitial lung disease (ILD) diagnosis may require surgical biopsy (SLB). While prior studies have described the epidemiology of ILDs among different races and ethnicities, pathologic clinical diagnoses based on SLBs associated with these demographics are unexplored. Methods We reviewed performed between 2000 2022 at University California San Francisco (UCSF) Chicago (UChicago) assessing histopathology using structured data collection forms. analyzed differences...
Background/Aims The efficacies of lopinavir-ritonavir or hydroxychloroquine remain to be determined in patients with coronavirus disease 2019 (COVID-19). To compare the virological and clinical responses treatment COVID-19 patients. Methods This retrospective cohort study included treated at a single center Korea from February 17 March 31, 2020. Patients concurrently those for less than 7 days were excluded. Time negative conversion viral RNA, time improvement, safety outcomes assessed after...
Background Foreign-body aspiration is common in children aged 6 months to 3 years. However, with the aging population and increasing prevalence of disabilities such as hemiparesis neuromuscular diseases adults, an increased incidence expected. Methods This was a multicenter retrospective, observational study four major referral hospitals Daegu, South Korea, between 2000 2019. We included patients over 18 years who were evaluated for tracheobronchial foreign-body by flexible bronchoscopy....
Purpose: The prevalence of carbapenem-resistant Enterobacterales (CRE) is rapidly increasing worldwide. Patients in the intensive care unit (ICU) are susceptible to CRE infections, and related mortality rate increased. It necessary understand strains risk factors for infection ICU, facilitate development effective prophylactic strategies treatments ICU patients. Methods: This observational study was conducted a tertiary hospital between 2016 2021. subjects were patients with cultured from...
Background Streptococcus pneumoniae is a leading cause of invasive bacterial disease in developed and developing countries. We studied the loop-mediated isothermal amplification (LAMP) technique to assess its suitability for detecting S. nucleic acid cerebrospinal fluid (CSF). Methodology/Principal Findings established an improved LAMP assay targeting lytA gene (Streptococcus [Sp] LAMP). The analytical specificity primers was validated by using 32 reference strains (10 seven...
Haemophilus influenzae type b (Hib) is one of the leading causes meningitis in developing countries. To establish and evaluate a novel loop-mediated isothermal amplification (LAMP) assay for Hib, we designed LAMP primer set targeting Hib-specific capsulation locus. detected 10 copies purified DNA 60-min reaction. This indicated that detection limit was >100-fold lower than limits both PCR bexA nested Hib (Hib PCR). No H. influenzae, other or control bacteria, detected. Linear determination...
Background The coronavirus disease (COVID-19) can manifest in a range of symptoms, including both asymptomatic systems which appear nearly non-existent to the patient, all way development acute respiratory distress syndrome (ARDS). Specifically, COVID-19-associated pneumonia develops into ARDS due rapid progression hypoxia, and although arterial blood gas analysis assist halting this deterioration, current environment provided by COVID-19 pandemic, has led an overall lack medical resources...
<i>Background:</i> To establish an easy and rapid method for evaluating pial collateral flow, we compared the Alberta Stroke Program Early CT Score (ASPECTS) on nonenhanced (NECT), conventional contrast-enhanced (CECT), angiography source images (CTA-SI) in patients with acute ischemic stroke. <i>Methods:</i> We reviewed 55 consecutive stroke involving anterior circulation who underwent thrombolysis within 6 h of referral to center. evaluated axial using NECT, CECT...
Abstract p62/SQSTM1 is known to act as a key mediator in the selective autophagy of protein aggregates, or aggrephagy, by steering ubiquitinated aggregates towards pathway. Here, we use yeast two-hybrid screen identify prefoldin-like chaperone UXT an interacting p62. We show that can bind well LB domain p62, and, possibly forming oligomer, increase p62 clustering for its efficient targeting thereby promoting formation body and clearance cargo via autophagy. also find ectopic expression human...
Bronchoalveolar lavage (BAL) is a necessary procedure for diagnosis of various lung diseases. High-flow nasal cannula (HFNC) oxygen delivery was recently introduced. This study aimed to investigate the safety and effectiveness HFNC supply during BAL in patients with acute respiratory failure (ARF).Patients who underwent while using at partial pressure arterial blood/fraction inspired (PaO₂/FiO₂; PF) ratio 300 or below among had been admitted from March 2013 May 2017 were retrospectively...
Abstract Background Surgical site infection (SSI) is the most common healthcare-associated infection. We report an outbreak of neurosurgical infections caused by Serratia marcescens after craniotomy in a tertiary care hospital. Methods Between August 6 and 21, 2018, five cases early-onset SSI S. were recorded 1786-bed Cultures collected from potential environmental sources healthcare workers. Whole-genome sequencing (WGS) was used to investigate genetic relationships among isolates. Results...
Plastic bronchitis is a rare disease characterized by marked airway obstruction, via the formation of large gelatinous or rigid cast. In Korea, there were few case reports with plastic not in adults, but children. So we report an adult who was diagnosed as eosinophilic casts, no history atopic and cardiac disease.