About
Contact & Profiles
A5053871479
Research Areas
- Biochemical effects in animals
- Connexins and lens biology
- Neuroscience of respiration and sleep
- Nicotinic Acetylcholine Receptors Study
University of Calgary
2020-2024
Abstract Opioid withdrawal is a liability of chronic opioid use and misuse, impacting people who prescription or illicit opioids. Hyperactive autonomic output underlies many the aversive symptoms that make it difficult to discontinue use. The locus coeruleus (LC) an important centre within brain with poorly defined role in withdrawal. We show here pannexin-1 (Panx1) channels expressed on microglia critically modulate LC activity during Within LC, we found spinally projecting tyrosine...
10.1038/s41467-024-50657-7
article
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cc-by
Nature Communications
2024-07-24
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