A5037182801- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Colorectal Cancer Treatments and Studies
- Tracheal and airway disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Respiratory Support and Mechanisms
- Head and Neck Surgical Oncology
- Gastric Cancer Management and Outcomes
- Congenital Heart Disease Studies
- Pleural and Pulmonary Diseases
- Inflammatory Myopathies and Dermatomyositis
- Esophageal and GI Pathology
- Cardiovascular Issues in Pregnancy
- Muscle and Compartmental Disorders
- Radiation Detection and Scintillator Technologies
- Particle physics theoretical and experimental studies
- Eosinophilic Disorders and Syndromes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Medical Imaging Techniques and Applications
- Occupational exposure and asthma
- Colorectal and Anal Carcinomas
- Salivary Gland Tumors Diagnosis and Treatment
Kyushu University
2023-2024
Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas
2024
Takarazuka City Hospital
2024
Kumamoto Medical Center
2015-2024
Izumi City General Hospital
2024
Kumamoto University
2011-2014
Kumamoto University Hospital
2011-2012
To examine whether the extent of fibroproliferative changes on high-resolution CT (HRCT) scan influences prognosis, ventilator dependency and associated outcomes in patients with early acute respiratory distress syndrome (ARDS).
Abstract The CALICE collaboration is developing highly granular electromagnetic and hadronic calorimeters for detectors at future energy frontier electron-positron colliders. After successful tests of a physics prototype, technological prototype the Analog Hadron Calorimeter has been built, based on design construction techniques scalable to collider detector. consists steel absorber structure active layers small scintillator tiles that are individually read out by directly coupled SiPMs....
Galectin (Gal)-9 plays a crucial role in the modulation of innate and adaptive immunity.To investigate whether Gal-9 murine acute lung injury (ALI) model.C57BL/6 mice were pretreated with by subcutaneous injection 24 48 hours before intranasal LPS inoculation.Gal-9 suppressed pathological changes ALI induced LPS. reduced levels proinflammatory cytokines chemokines, such as tumor necrosis factor (TNF)-α, IL-1β, IL-6, keratinocyte-derived cytokine; decreased neutrophils; increased IL-10...
We present 3 cases of rapidly progressive interstitial pneumonia (RPIP) associated with clinically amyopathic dermatomyositis (C-ADM) that were treated two courses direct hemoperfusion polymyxin B-immobilized fiber column (PMX-DHP). Despite initial treatment high-dose corticosteroids, pulsed cyclophosphamide, and cyclosporine, the lung disease hypoxemia deteriorated in all patients. After PMX-DHP treatment, PaO2/FiO2 ratio serum LDH KL-6 improved, abnormal shadows chest high-resolution...
We retrospectively evaluated whether preoperative percutaneous transthoracic needle biopsy (PTNB) affected the incidence of pleural recurrence in pathological stage I lung cancer patients. Pleural occurred pure solid nodule (PSN) cases but not ground-glass cases, as using thin-section computed tomographic imaging. When were restricted to sub-pleural PSN, tended be higher a PTNB group (63 patients diagnosed by PTNB) than non-PTNB (86 transbronchial or intraoperative diagnosis) (25% vs. 4%, p...
Abstract Lessons Learned Alectinib confers a pronounced survival benefit in patients with ALK rearrangement-positive non-small cell lung cancer and poor performance status. Survival of alectinib for status was consistent regardless the presence central nervous system metastases. Background We previously reported marked objective response rate (ORR) safety treatment (NSCLC) (PS) Lung Oncology Group Kyushu (LOGiK) 1401 study. It remained unclear, however, whether might also confer long-term...
A neural network for software compensation was developed the highly granular CALICE Analogue Hadronic Calorimeter (AHCAL). The uses spatial and temporal event information from AHCAL energy information, which is expected to improve sensitivity shower development neutron fraction of hadron shower. method produced a depth-dependent weighting time-dependent threshold enhancing deposits consistent with timescale evaporation neutrons. Additionally, it observed learn an energy-weighting indicative...
Background/Aim: The survival benefit of first-line epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy without pleurodesis in EGFR-mutant lung adenocarcinoma patients with malignant pleural effusions (MPE) remains unclear. Patients and Methods: We retrospectively evaluated overall (OS) among EGFR wild-type MPE who received chemotherapy (CT+PLD) (CT-PLD), EGFR-TKI (TKI+PLD) (TKI-PLD). Results: There was no difference OS between the CT+PLD CT-PLD groups (10.8 months...
Transbronchial microwave ablation (MWA) can be performed safely in patients with malignant central airway obstruction (MCAO), under moderate sedation and a high fraction of inspired oxygen.We retrospectively evaluated the difference overall survival (OS) after transbronchial interventions (TBIs) between MCAO endoluminal or mixed-type who were treated by MWA (MWA group, n=34) those extraluminal stent placement (STP) (STP n=27).The OS was longer group than STP (10.2 months vs. 4.5 months,...
In EGFR-mutant NSCLC patients with oligo-progression disease (oligo-PD) after the EGFR-TKI failure, additional local ablative therapy (LAT) including stereotactic radiotherapy reportedly extends duration of current and prolongs survival times. clinical practice, however, all cannot receive LAT for oligo-PD. We retrospectively evaluated efficacy tolerability bevacizumab as an alternative to oligo-PD failure in previously treated lung adenocarcinoma (median number previous therapies, 2...
We reported that epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor re-administration (TKI-R) might be salvage therapy in patients with advanced non-small cell lung cancer after recovery from EGFR-TKI-induced interstitial disease (ILD). Here we retrospectively evaluated whether chemotherapy (CT-R) was effective chemotherapy-induced ILD. After providing their informed consent due to the risk of severe ILD, five received CT-R and six TKI-R oral administration 0.5 mg/kg...
We retrospectively evaluated whether the ratio KL-6 to SLX in serum (K/S ratio) before chemotherapy was a predictor for occurrence of drug-induced interstitial lung disease (D-ILD) cancer patients with idiopathic pneumonias (IIPs). D-ILD occurred 8 20 IIPs-positive cases and 14 100 IIPs-negative (40 vs. 14%, p = .015). In cases, high K/S (>20) first-line had tendency increase risk (p .085). Serum may be useful IIPs.
Among advanced non-small cell lung cancer (NSCLC) patients in whom grade 2/3 immune-related adverse events (irAEs) that had developed during the initial immune checkpoint inhibitor (ICI) therapy been successfully controlled, we experienced three ICI was resumed at diagnosis of progressive disease (PD group, n = 3) and four it immediately after successful control irAEs (non-PD 4). The tumor response rate, rate to progression-free survival from resumption were 0%, 0% 2 months PD group 25%, 75%...
We present 3 cases of rapidly progressive interstitial pneumonia (RPIP) associated with clinically amyopathic dermatomyositis (C-ADM) that were treated two courses direct hemoperfusion polymyxin B-immobilized fiber column (PMX-DHP). Despite initial treatment high-dose corticosteroids, pulsed cyclophosphamide, and cyclosporine, the lung disease hypoxemia deteriorated in all patients. After PMX-DHP treatment, PaO2/FiO2 ratio serum LDH KL-6 improved, abnormal shadows chest high-resolution...