- Neurogenesis and neuroplasticity mechanisms
- Neurological Disease Mechanisms and Treatments
- Adipose Tissue and Metabolism
- Sperm and Testicular Function
- Neuroscience and Neuropharmacology Research
- Cannabis and Cannabinoid Research
- Curcumin's Biomedical Applications
- Mesenchymal stem cell research
- Sirtuins and Resveratrol in Medicine
- Reproductive Biology and Fertility
- Nerve injury and regeneration
- Synthesis and Characterization of Heterocyclic Compounds
- Adenosine and Purinergic Signaling
- Neurological Disorders and Treatments
- Ovarian function and disorders
- Hormonal and reproductive studies
- Neuroinflammation and Neurodegeneration Mechanisms
- RNA Interference and Gene Delivery
- Diet and metabolism studies
- Ginger and Zingiberaceae research
- Spinal Cord Injury Research
- Pancreatic function and diabetes
- Apelin-related biomedical research
- Proteins in Food Systems
- Circular RNAs in diseases
Urmia University
2015-2025
Urmia University of Medical Sciences
2014-2024
Endocrinology Research Center
2022
Iran University of Medical Sciences
2009
Frozen- thawed embryo transfer is an essential part of ART treatment and outcomes this procedure are associated with several clinical factors. Several studies have showed increase level IVF in women sufficient vitamin D.whether D insufficiency can improve pregnancy rates frozen-thawed cycles.This interventional, randomized trial. Serum 25-(OH) 128 who had undergone IVF/ICSI cryopreservation embryos was checked. One hundred fourteen infertile insufficient serum (less than 30 ng/ml) were...
Oxidative stress is a major contributor to diabetes, which can lead testicular damage and infertility.
Exposure to extremely low-frequency electromagnetic fields may induce constant modulation in neuronal plasticity. In recent years, tremendous efforts have been made design a suitable strategy for enhancing adult neurogenesis, which seems be deterred due brain senescence and several neurodegenerative diseases. this study, we evaluated the effects of ELF-EMF on neurogenesis memory, following treatment with trimethyltin chloride (TMT) as neurotoxicant. The mice all groups (n = 56) were injected...
Cell therapy is the most advanced treatment of cerebral ischemia, nowadays. Herein, we discuss neuroprotective effects bone marrow mesenchymal stem cells (BMSCs) on rat hippocampal following intravenous injection these in an ischemia-reperfusion model. Adult male Wistar rats were divided into 5 groups: control, sham (surgery without blockage common carotid arteries), ischemia (common arteries blocked for 30 min prior to reperfusion), vehicle (7 days after PBS was injected via tail vein), and...
Introduction: Aging-dependent decline in the angiogenesis of heart is a risk factor for cardiovascular disease. This study was aimed to characterize effect exercise on alterations and molecular mediators which are related under aging condition. Methods: Twenty-one male Wistar rats were assigned into three groups: young, aged, exercise. Aged animals group run treadmill 8 weeks. At end, samples collected used histological evaluation , determination by immunostaining PECAM-1/ CD31 expressions...
Background: Oxidative stress is a major contributor to diabetes mellitus (DM), which leads testicular damage and infertility. Objective: The aim of this study was investigate the effects glibenclamide (GL) as chemical medicine troxerutin (TR) an herbal agent on sperm parameters histopathological changes testis in diabetic male rats. Materials Methods: Forty Wistar rats (230-260 gr) were randomly divided into 5 groups (n = 8/each), including control, (D), GL, TR, GL+TR. DM induced by...
Emerging studies of treating spinal cord injury (SCI) with adult stem cells led us to evaluate the effects transplantation hair follicle in rats a compression-induced lesion. Here, we proposed hypothesis that rat cell can promote recovery injured cord. Compression-induced was induced Wistar this study. The bulge area vibrissa follicles isolated, cultivated and characterized nestin as marker. 5-Bromo-2'-deoxyuridine (BrdU) labeled were transplanted into injury. Immunohistochemical staining...
Differential diagnosis of hydatidiform moles from non-molar specimens as well their sub-classification such complete and partial are important for clinical management accurate risk assessment persistent gestational trophoblastic disease, but based solely on histomorphology suffers poor interobserver intraobserver reproducibility.This study was undertaken to determine whether the expression Ki-67 protein could differentiate these entities.We performed immunohistochemical staining in 19 molar...
Abstract Objectives Diabetes mellitus is one of the most common metabolic diseases. Tropisetron, as a 5-HT3 receptor antagonist, has considerable role in inflammation and oxidative stress lowering. This study aimed to investigate effect this antagonist on insulin secretion male diabetic rats possible mechanisms. Methods Animals were divided into five equal groups; control, tropisetron, diabetes, tropisetron–diabetes glibenclamide–diabetes (7 each group). Tropisetron glibenclamide...
As a serotonin antagonist, tropisetron positively affects blood glucose lowering, insulin synthesis, pancreas inflammation, and apoptosis in diabetes. Reproductive disorders are one of the diabetes-induced chronic complications. The present study aimed to evaluate effect on testicular its signaling pathway, mir146a. To this end, animals were assigned control, tropisetron, diabetes (DM), DM-tropisetron, DM-glibenclamide groups. Streptozotocin (50 mg/kg) was intraperitoneally injected provide...