A5073333360- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Advancements in Transdermal Drug Delivery
- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- melanin and skin pigmentation
- Endoplasmic Reticulum Stress and Disease
- Curcumin's Biomedical Applications
- Essential Oils and Antimicrobial Activity
- Asthma and respiratory diseases
- Skin Protection and Aging
Institute of Science and Technology Austria
2024
Medical University of Vienna
2019-2022
University Medical Center of the Johannes Gutenberg University Mainz
2019
Johannes Gutenberg University Mainz
2019
Medical University of Graz
2019
Immunologie, Immunopathologie et Chimie Thérapeutique
2019
Centre National de la Recherche Scientifique
2019
Institut de Biologie Moléculaire et Cellulaire
2019
The endoplasmic reticulum-associated protein reticulon 1A (RTN1A) is primarily expressed in neuronal tissues but was recently identified also specifically cells of the dendritic cell (DC) lineage, including epidermal Langerhans (LCs) and dermal DCs human skin. In this study, we found that mice major histocompatibility complex class II (MHCII) + CD207 LCs not express RTN1A. Further, RTN1A expression CD45 MHCII lymph node spleen thymus. Of note, low adult skin as well emigrated nodes...
Skin is an active immune organ where professional antigen-presenting cells such as epidermal Langerhans (LCs) link innate and adaptive responses. While Reticulon 1A (RTN1A) was recently identified in LCs dendritic cutaneous lymphoid tissues of humans mice, its function still unclear. Here, we studied the involvement this protein cytoskeletal remodeling responses toward pathogens by stimulation Toll-like receptors (TLRs) resident (rLCs) emigrated (eLCs) human epidermis ex vivo a transgenic...
Reticulon 1A (RTN1A) is an endoplasmic reticulum-associated protein and besides its expression in neuronal tissues, a marker for cells of the dendritic lineage, including epidermal Langerhans (LCs) dermal (DCs) humans.Expression RTN1A before appearance LC markers during skin development suggests that it may play role differentiation/migration process.To obtain prenatal human challenging, therefore studies were continued wild-type C57BL/6 mice to unravel cutaneous physiology.Intriguingly,...
Abstract Skin is an active immune organ where professional antigen-presenting cells such as epidermal Langerhans (LCs) link innate and adaptive responses. While Reticulon 1A (RTN1A) was recently identified in LCs dendritic cutaneous lymphoid tissues of humans mice, its function still unclear. Here, we studied the involvement this protein cytoskeletal remodeling responses towards pathogens by stimulation Toll-like receptors (TLRs) resident (rLCs) emigrated (eLCs) human epidermis ex vivo a...