A5101828934- Inhalation and Respiratory Drug Delivery
- Venous Thromboembolism Diagnosis and Management
- Respiratory Support and Mechanisms
- Ocular Infections and Treatments
- Magnesium Alloys: Properties and Applications
- Corneal surgery and disorders
- Central Venous Catheters and Hemodialysis
- Hepatitis Viruses Studies and Epidemiology
- Glaucoma and retinal disorders
- Bacillus and Francisella bacterial research
- Pediatric Pain Management Techniques
- Lung Cancer Diagnosis and Treatment
- COVID-19 epidemiological studies
- RNA Interference and Gene Delivery
- Intraocular Surgery and Lenses
- Neutropenia and Cancer Infections
- Corrosion Behavior and Inhibition
- Atrial Fibrillation Management and Outcomes
- Nosocomial Infections in ICU
- Aluminum Alloy Microstructure Properties
- Advanced Radiotherapy Techniques
- Blood properties and coagulation
- Pharmacy and Medical Practices
- Zoonotic diseases and public health
- Pain Management and Opioid Use
University of Science and Technology of China
2017-2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2019-2024
Chongqing Medical University
2019-2024
Henan University of Science and Technology
2021-2024
Xiamen University
2024
Harbin Medical University
2009-2023
First Affiliated Hospital of Harbin Medical University
2009-2022
Beijing Institute of Technology
2020
China Medical University
2018
Jiangsu University
2016
Abstract Few prospective studies have reported the cumulative incidence of venous thromboembolism (VTE) in intensive care unit (ICU), especially for patients receiving guideline-recommended VTE prophylaxis. We aimed to design a observational study investigate and risk factors ICU-acquired those populations. prospectively studied 281 consecutively included ICU at single center. All provided informed consent. Patients received ultrasound evaluation were followed before discharge or within 28...
From the perspective of history science and technology, this paper delves into global development high-level biosafety laboratories, establishment related legal frameworks, evolution safety standards. The importance these laboratories within context national security is emphasized. This begins with an overview laboratories’ origins technological advancements. Then, it provides a detailed analysis institutional frameworks that different countries have developed in field biosafety. By...
The orphan nuclear receptor Nur77 is emerging as an attractive target for cancer therapy, and activating Nur77's non-genotypic anticancer function has demonstrated strong therapeutic potential. However, few site B ligands have been identified excellent compounds. There are no co-crystal structures of effective agents at B, which greatly limits the development novel ligands. Moreover, lack pharmaceutical restricts proof concept. Herein, we developed a first-in-class ligand (NB1) that...
Intestinal obstruction in neonates is a common problem that requires prompt diagnosis and treatment, ultrasound could be potential tool for it. The purpose of this study was to investigate the accuracy ultrasonography diagnosing identifying cause intestinal neonates, corresponding ultrasonic manifestations, as well utilize diagnostic method.We conducted retrospective all neonatal our institute between 2009 2022. identification its etiology compared with results operation gold standard.The...
According to the World Health Organization, about 20 million people are infected with Hepatitis E every year. In 2015, there were 44,000 deaths due HEV infection worldwide. Food, water and climate key factors that affect outbreak of E. This paper presents an ensemble learning model for prediction by studying correlation between historical epidemic cases hepatitis environmental (water quality meteorological data). Environmental include many features, ones most relevant selected input into...
The dynamic recrystallization (DRX) behavior and hot workability of Mg–8Gd–4Sm–1Zn–0.5Zr alloys are investigated by the Gleeble‐1500 test machine. tests performed at 350–470 °C with a strain rate 0.002–1 s −1 . results show that stress–strain curves exhibit typical single‐peak DRX behavior. critical model alloy is constructed according to inflection characteristics work hardening curve. kinetic Avrami equation. 3D processing maps obtained based on material model. mechanisms instability...
From the perspective of science and technology history, we review development history key events global biosafety laboratories to deepen our understanding biosafety. The construction reveals complex interactions between science, social needs, public health safety, national security. recognition laboratory infection incidents in late 19th century potential hazards biological warfare biotechnology mid-20th century, gradual establishment a level system high-level 21st respond infectious disease...
<h3>Background/aims</h3> This study was to explore the 1-year interim efficacy and safety of canaloplasty for primary open-angle glaucoma (POAG) with failed filtration surgery (GFS) but an intact Schlemm9s canal (SC). <h3>Methods</h3> a single-surgeon prospective clinical study. Patients POAG scheduled were included divided into two groups (with or without GFS). The status SC determined by gonioscopy ultrasound biomicroscopy. Primary outcome measures intraocular pressure (IOP) medication use...
Objective. Atherosclerotic is a chronic systemic disease that may occur in multiple vascular beds, including the carotid arteries, renal lower limb and cerebral vessels. Coronary atherosclerosis shares similar risk factors, pathogenesis, pathophysiological basis with atherosclerotic lesions of arteries at these sites. Arterial ultrasound assessment data were used to explore correlation CHD their severity number lesion branches, as well evaluate its value predicting risk, combination...
This randomized clinical trial (RCT) is aimed at exploring the best nebulizer position for aerosol delivery within mechanical ventilation (MV) circuitry. study enrolled 75 intubated and MV patients with respiratory failure randomly divided them into three groups. The of in group A was between tracheal tube Y-piece. For B, placed inspiratory limb near ventilator water cup (80 cm away from Y-piece). C, inlet heated humidifier. An indirect competitive enzyme-linked immunosorbent assay (ELISA)...
Androgen receptor (AR) signaling is involved in the initiation and progression of prostate cancer (PCa), which most frequently diagnosed nonskin remains a leading cause cancer-related death men. Further investigation involvement AR PCa urgently needed. In present study, we performed yeast two-hybrid screen demonstrated that SERTA domain-containing protein 1 (Sertad1) novel AR-binding binds to ligand binding domain (LBD). The between AR-LBD Sertad1 was confirmed by glutathione S-transferase...
Objective: This analysis was conducted to clarify risk factors for chemotherapy-induced leukopenia (CIL) in lung cancer. Methods: A retrospective study on data from 358 patients with cancer who received chemotherapy. Results: Among cases of chemotherapy, a total 240 experienced CIL, rate 67%. The demographic including gender (P = 0.795), age 0.134), presence selected chronic comorbidities 0.23) were not significantly different the two groups. weight loss rate, PS score, sub-normal pre-WBC...
This study aimed to determine the knowledge and current practices of ICU nurses regarding aerosol therapy for patients with invasive mechanical ventilation in China.Aerosol is a routine operation intensive care unit (ICU) nurses; however, evidence insufficient China.A total 433 hospitals 92 cities (including 31 capital cities) provinces China participated study.A questionnaire was used investigate treated ventilation, including 42 questions covering five aspects: sociodemographic...
Preoperative computed tomography (CT)-guided localization of small pulmonary nodules (SPNs) is the major approach for accurate intraoperative visualization in video-assisted thoracoscopic surgery (VATS). However, this interventional procedure has certain risks and may challenge to less experienced junior doctors. This study aims evaluate feasibility efficacy robotic-assisted CT-guided preoperative with modified hook-wire needles before VATS.
Background ICU patients have a high incidence of VTE. The American College Chest Physicians antithrombotic practice guidelines recommend assessing the risk VTE in all patients. Although several assessment tools exist to evaluate factors among hospitalized patients, there is no validated tool specifically for Methods A retrospective corhort study was conducted between June 2018 and October 2022. We obtained data from electronic medical records with variety diagnoses admitted mixed ICU....
Objective To investigate the effect of chain management on education among hypertensive patients community. Methods A total 144 cases hypertension in community were selected as research objects, they divided into control group(72 cases, from February to July 2015) and countryside group (72 September 2015 2016).The was given routine education, received with management. The treatment compliance blood pressure values compared between two groups before after...
Abstract The effects of aging time on corrosion behavior Mg-4Nd-2Gd-0.5Zr alloy in 3.5% NaCl solution were investigated by microanalysis, weight loss test and electrochemical test. results show that the rate decreases first then increases with extension time. Aging treatment alters grain size distribution second phases. phases are key factors affecting magnesium alloy. Among tested alloys, T6-8 h shows lowest rate, which is mainly attributed to continuous restricting expansion corrosion,...