A5003219872- Paraquat toxicity studies and treatments
- Heavy Metal Exposure and Toxicity
- Drug-Induced Hepatotoxicity and Protection
- Mycotoxins in Agriculture and Food
- Pain Mechanisms and Treatments
- Trace Elements in Health
- Pesticide Exposure and Toxicity
- Circadian rhythm and melatonin
- Carcinogens and Genotoxicity Assessment
- Neuroscience and Neuropharmacology Research
- Effects of Radiation Exposure
- Veterinary Pharmacology and Anesthesia
- Electron Spin Resonance Studies
- Effects and risks of endocrine disrupting chemicals
- Heme Oxygenase-1 and Carbon Monoxide
- Tryptophan and brain disorders
- Nitric Oxide and Endothelin Effects
- Protein Interaction Studies and Fluorescence Analysis
- Stress Responses and Cortisol
- Liver Disease Diagnosis and Treatment
- Radioactive element chemistry and processing
- Phytochemistry and Biological Activities
- Vitamin C and Antioxidants Research
- Pesticide Residue Analysis and Safety
- Radioactivity and Radon Measurements
Tehran University of Medical Sciences
2016-2025
Iran Nanotechnology Initiative Council
2018
University of Tehran
1994-2017
Guilan University of Medical Sciences
2016
Iran University of Medical Sciences
2016
Shahid Beheshti University of Medical Sciences
2013
Tabriz University of Medical Sciences
2013
Pharmaceutical Biotechnology (Czechia)
2009
Iran University of Science and Technology
2008
Islamic Azad University North Tehran Branch
2006
Vanadium as a trace element is considered essential for animals; however it has not yet been recognized micronutrient humans. Most of the information on biological effects vanadium was related to metal's insulin-like, anti-hyperlipidemic and anticancer properties in low concentrations. According previous literature, mitochondria were proposed an important target cytotoxicity. In this study, mitochondrial toxicity mechanisms sodium metavanadate (vanadium V or V5+) investigated isolated...
Recent epidemiological studies have demonstrated that metformin lowers the risk of several types cancer in diabetic patients. Matrix metalloproteinases (MMPs) play a crucial role degradation vascular basement membrane extracellular matrix proteins, thereby promoting endothelial cell invasion, migration and angiogenesis incidence progression tumors. The aim this study was to investigate effects on human umbilical vein (HUVEC) proliferation migration, as well MMP-2 MMP-9 expression. Cell...
Objective: The objective of this study was to investigate the possible protective effects pentoxifylline as a phosphodiesterase-5 inhibitor on malathion-induced oxidative damage rat brain mitochondria. Methods: Rats received malathion (200 mg/kg/day) and (PTX, 50 in combination or alone. Alpha-tocopherol (AT, 15 used positive standard. After 1 week treatment, blood, whole tissue, mitochondria were isolated. activity enzymatic scavengers such glutathione peroxidase (GPx), catalase (CAT),...
Abstract Catecholamine neurotransmitters, generally including dopamine (DA), epinephrine (EP) and norepinephrine (NE) are known as substantial indicators of various neurological diseases. Simultaneous detection these compounds their metabolites is highly recommended in early clinical diagnosis. To this aim, the present contribution, a high performance colorimetric sensor array has been proposed for discrimination catecholamines based on reducing ability to deposit silver surface gold...
Abstract Objectives Both excessive and insufficient angiogenesis are associated with progression of diabetic complications, which poor is an important feature. Currently, adipose‐derived stem cells ( ADSC s) considered to be a promising source aid therapeutic neovascularization. However, functionality these impaired by diabetes can result from defect in hypoxia‐inducible factor‐1 HIF ‐1), key mediator involved In the current study, we sought explore effectiveness pharmacological priming...
Depleted uranium (DU) is emerging as an environmental pollutant primarily due to its military applications. Gulf War veterans with embedded DU showed cognitive disorders that suggest the central nervous system a target of DU. Recent evidence has suggested could induce oxidative stress and mitochondrial dysfunction in brain tissue. However, underlying mechanisms toxicity mitochondria are not yet well understood. Brain were obtained using differential centrifugation incubated different...