A5062782865- Bone Metabolism and Diseases
- Bone health and treatments
- Bone Tissue Engineering Materials
- Bone health and osteoporosis research
- Orthopaedic implants and arthroplasty
- Craniofacial Disorders and Treatments
- Inflammatory mediators and NSAID effects
- Bone and Joint Diseases
- Bone fractures and treatments
- Cleft Lip and Palate Research
- Facial Nerve Paralysis Treatment and Research
- Cytokine Signaling Pathways and Interactions
- Dental Implant Techniques and Outcomes
- Oral and Maxillofacial Pathology
- Orthodontics and Dentofacial Orthopedics
- Mesenchymal stem cell research
- Nerve injury and regeneration
- Metabolism, Diabetes, and Cancer
- Titanium Alloys Microstructure and Properties
- Laser Applications in Dentistry and Medicine
- Interpreting and Communication in Healthcare
- RNA Interference and Gene Delivery
- Medical and Biological Sciences
- Botulinum Toxin and Related Neurological Disorders
- Heterotopic Ossification and Related Conditions
North China University of Science and Technology
2011-2024
Hebei University
2013
Sichuan University
2004-2009
This paper reviews the principles, advantages and disadvantages, scope of application different processes for preparation drug-carrying microspheres polylactic acid (PLA) its copolymers, explores potential PLA drug delivery, tissue engineering fluorescent labeling, etc. It also summarizes limitations current technology, proposes to optimize system through design bilayer structured, responsive multifunctional integrated microspheres, with a view providing theoretical basis technical support...
Understanding the response of mesenchymal stem cells (MSCs) to mechanical strain and their consequent gene expression patterns will broaden our knowledge mechanobiology distraction osteogenesis. In this study, a single period cyclic stretch (0.5 Hz, 2,000 μɛ) was performed on rat bone marrow MSCs. Cellular proliferation alkaline phosphatase (ALP) activity examined. The mRNA six bone‐related genes (Ets‐1, bFGF, IGF‐II, TGF‐β, Cbfa1 ALP) detected using real‐time quantitative RT‐PCR. results...
Bisphosphonates, the main drugs to treat osteoporosis, have been shown protect against bone loss in diabetic osteoporosis. However, effects of bisphosphonate zoledronate (ZOL) on osteoclast differentiation and function a high glucose environment as well involvement adenosine activated protein kinase (AMPK) pathway remain unclear. In current study, RAW264.7 cells were induced into osteoclasts, divided low glucose, + ZOL, ZOL groups, which tested for cell proliferation, migration, integrity...
Osteopenia, a preclinical state of osteoporosis, restricts the application adult orthodontic implant anchorage and tooth implantation. Strontium (Sr) is able to promote bone formation inhibit absorption. The aim present study was evaluate new method for improving success rate dental In this study, an electrochemical deposition (ECD) used prepare Sr coating on titanium implant. composition investigated by energy dispersive X‑ray spectroscopy diffraction, surface morphology studied using...
Abstract This study was designed to observe the effects of bone morphogenetic protein‐7 (BMP‐7) ex vivo gene therapy on callus formation during rat mandibular distraction osteogenesis (DO). Fifty‐four Sprague‐Dawley rats underwent osteodistraction right mandible and were then randomly divided into three groups. Immediately after distraction, autologous marrow mesenchymal stem cells (MSCs) transfected with BMP‐7, MSCs untransfected physiological saline injected gaps mandibles in groups A, B,...
Surface modification techniques have been applied to generate titanium implant surfaces that promote osseointegration for use in dental applications. In this study, strontium-doped brushite coatings were deposited on by electrochemical deposition. The phase composition of the coating was investigated energy dispersive X-ray spectroscopy and diffraction. surface morphologies studied through scanning electron microscopy, cytocompatibility bioactivity evaluated using cultured osteoblasts....
Titanium (Ti) and Ti alloys are widely used biomaterials, but they lack osteogenic capability for rapid bone integration. To improve osseointegration of implants, TiO
The plasma immersion ion implantation and deposition (PIIID) technique was used to implant zinc (Zn) ions into smooth surfaces of pure titanium (Ti) disks for investigation tooth surface modification. aim the present study evaluate structure chemical composition a modified Ti following Zn examine effect such modification on osteoblast biocompatibility. Using PIIID technique, were deposited onto disks. physical layers characterized by scanning electron microscopy (SEM) X‑ray photoelectron...
Bacterial infection and poor osseointegration are two critical issues that need to be solved for long-term use of titanium implants.
To evaluate autogenous vein grafts and inside-out as conduits for the defects repair in rabbit facial nerves. The 10 mm segments of buccal division nerve were transected 48 rabbits this study. Then gaps immediately repaired by or different groups. All animals underwent whisker movement test electrophysiologic during following 16 weeks at time points postoperatively. Subsequently, histological examination was performed to observe regeneration morphologically. At 8 after operation, has...
To investigate the effect of zoledronate (ZOL) on osteoclast differentiation and bone resorption under high glucose, regulation mechanism p38 mitogen activated kinase (p38 MAPK) signaling pathway in this process.RAW264.7 cells were divided into four groups: low group, low+ZOL group high+ZOL after induced osteoclasts. Cell proliferation activity was determined by MTT assay. The migration RAW264.7 examined Optical microscopy. Immunofluorescence microscopy used to observe cytoskeleton sealing...