A5100778836- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Cancer-related molecular mechanisms research
- Cancer, Hypoxia, and Metabolism
- Congenital Diaphragmatic Hernia Studies
- Cancer Research and Treatments
- Ferroptosis and cancer prognosis
- dental development and anomalies
- RNA modifications and cancer
- RNA Research and Splicing
- MicroRNA in disease regulation
- Bone and Dental Protein Studies
- Immune cells in cancer
- Atherosclerosis and Cardiovascular Diseases
- Cancer Genomics and Diagnostics
- Bone fractures and treatments
- Air Quality and Health Impacts
- Magnetic properties of thin films
- Magnetic Properties of Alloys
- Carcinogens and Genotoxicity Assessment
- Ubiquitin and proteasome pathways
- Immune Cell Function and Interaction
- Cancer Cells and Metastasis
- Angiogenesis and VEGF in Cancer
- Mesenchymal stem cell research
Jiangsu University
2024
Southeast University
2022
Jiangxi Provincial People's Hospital
2020-2022
Nanchang University
2016-2022
First People's Hospital of Yunnan Province
2019
Memorial Sloan Kettering Cancer Center
2019
Shanghai University of Traditional Chinese Medicine
2019
Sichuan University
2006-2017
State Key Laboratory of Oral Diseases
2017
Data Storage Institute
2008
Long noncoding RNA, long intergenic non-protein-coding RNA p53-induced transcript (LINC-PINT) was showed to be involved in cancer development. However, the biological effect of LINC-PINT on non-small cell lung (NSCLC) remains unknown. Here, we aimed investigate role and underlying mechanism NSCLC. Quantitative real-time polymerase chain reaction (qRT-PCR) used measure level NSCLC tissues lines. Cell counting kit-8 (CCK-8), flow cytometry, migration transwell invasion assays were...
Abstract This study was designed to observe the effects of bone morphogenetic protein‐7 (BMP‐7) ex vivo gene therapy on callus formation during rat mandibular distraction osteogenesis (DO). Fifty‐four Sprague‐Dawley rats underwent osteodistraction right mandible and were then randomly divided into three groups. Immediately after distraction, autologous marrow mesenchymal stem cells (MSCs) transfected with BMP‐7, MSCs untransfected physiological saline injected gaps mandibles in groups A, B,...
Abstract Emerging evidence indicates that hypoxia and immunity play important roles in tumorigenesis development. However, the hypoxia-immune-related prognostic risk model has not been established cervical cancer (CC). We aimed to construct a model, which potential application predicting prognosis of CC patients response targeted therapy. The RNA-seq data corresponding clinical information were retrieved from Cancer Genome Atlas (TCGA) database. status immune evaluated using Consensus...
CSCC is a systemic disease involving polygenic alteration and multiple steps, HIF VEGF are closely associated with tumorigenesis. Specimens surgically resected from 64 cases of 22 normal cervical tissue were selected randomly to detect the expression HIF-2 α in for exploring their clinical significance; information regarding age, lymph node metastasis, FIGO staging collected as well; was detected by qPCR immunohistochemistry. We found that mRNA significantly higher than tissues showed...
Abstract Long noncoding RNA 01296 (Lnc01296) is dysregulated in malignant tumors. However, the detailed effect of Linc01296 on hepatocellular carcinoma (HCC) remains largely unknown. In this study, we identified biological role HCC. The levels HCC tissues and a panel cell lines were assessed by quantitative real-time polymerase chain reaction (qRT-PCR). effects progression explored using Cell Counting Kit-8 (CCK-8), flow cytometry, migration Transwell invasion assays. interactions among...
Proprotein convertase subtilisin/kexin type 9 (PCSK9) participates in the development of various cancers, including hepatocellular carcinoma (HCC). Here, we attempted to reveal underlying mechanism PCSK9 HCC.Tumor tissues and adjacent were separated from HCC patients detect expression. Then, was overexpressed or silenced cells (MHCC97H Huh7), then cell supernatant incubated with THP-1 macrophages. OX40L neutralizing antibody (nAb) used inhibit activity. The expression macrophage markers...
Structural and magnetic properties of SmCo5 thin films grown on glass substrates with a Cr underlayer were investigated. The nanocrystalline film (112¯0) texture exhibited high in-plane intrinsic coercivity up to 26.5 kOe large anisotropy. crystallinity the layer plays an important role, which is strongly dependent morphology underlayer. A smooth (200) good desired for performance. This work demonstrates process achieve anisotropy deposited at relatively low temperature (400 °C).
Colorectal cancer (CRC) is the third most common solid tumor in world and shows resistance to several immunotherapies, particularly immune checkpoint blockade which has therapeutic effects on many other types of cancer. T cell (Treg) represents one main populations effector cells antitumor immunity, been considered as a double-edged sword during progression colon carcinogenesis. Our previous studies showed that traditional Chinese herbs had potential anticancer improving quality life effect....
Abstract Metastases are responsible for majority cancer related deaths. Disseminated tumor cells (DTCs) gain a diverse array of metastatic traits in order to adapt and survive within different microenvironments, making them very difficult therapeutically target. Remarkably, regardless the secondary organ, DTCs thrive perivascular niches. Using xenograft syngeneic models metastasis mouse, we found that upon extravasation, neuronal cell adhesion molecule L1 (L1CAM) expressed by engages...