Rhoptry protein 18 (ROP18) is a key virulence factor secreted into host cells during the invasion of Toxoplasma gondii ( T. gondii) and plays an important role in pathogenesis infection. Due to its potential as vaccine candidate, this study aimed characterize several properties ROP18 (TgROP18) support inclusion formulations. Using range bioinformatics tools, we investigated T-cell B-cell epitopes, physicochemical properties, subcellular localization, transmembrane domains, tertiary secondary...

Microsporidia are obligate intracellular parasites that produce spores. The infections caused by these mostly considered to be opportunistic in immunodeficient patients. Because of the zoonotic nature microsporidia as well increasing prevalence immunodeficiency diseases, aim this study was evaluate molecular diagnosis Enterocytozoon bieneusi (E. bieneusi) and Encephalitozoon spp. exotic birds southwestern Iran. Initially, 816 stool specimens were collected stained modified trichrome (Weber)...

AMA Javaherizadeh H, Khademvatan S, Soltani Torabizadeh M, Yousefi E. Distribution of haematological indices among subjects with Blastocystis hominis infection compared to controls. Gastroenterology Review/Przegląd Gastroenterologiczny. 2014;9(1):38-42. doi:10.5114/pg.2014.40849. APA Javaherizadeh, H., Khademvatan, S., Soltani, Torabizadeh, M., & Yousefi, (2014). Gastroenterologiczny, 9(1), 38-42. https://doi.org/10.5114/pg.2014.40849 Chicago Hazhir, Shahram Shahrzad Mehdi and Elham Yousefi....

The Toxoplasma gondii calcium-dependent protein kinase-3 (CDPK3) is a key enzyme for parasite egress, control of permeabilization in parasitophorous vacuole membrane and tissue cyst formation. In this study, we comprehensively explored the bioinformatics features to improve vaccine design against T. gondii.Various web servers were employed analysis physico-chemical properties, post-translational modifications, localization subcellular milieu, secondary tertiary structures, as well B-cell,...

Abstract Objectives In this study, the seroprevalence of anti- Toxoplasma gondii ( T. ) specific antibodies in patients undergoing hemodialysis compared to control group were evaluated. case–control 200 (HDP) and 100 healthy controls participated. The (IgG/IgM) both groups tested using enzyme-linked immunosorbent assay (ELISA) method. A structured questionnaire containing some demographic information was completed for each person case groups. Results overall infection 49.5% (99/200) 23.0%...

Background. This research was aimed at evaluating the seroprevalence of acute and chronic Toxoplasma gondii (T. gondii) infection in pregnant women related risk factors southwest Iran. Methods. In this cross-sectional study, eighty-eight were included from October 2019 to December 2019. The presence anti-T. IgM IgG antibodies measured using enzyme-linked immunosorbent assay (ELISA). addition, a questionnaire consisting demographic information completed for each subject. Results. overall T....

<p class="p1">The agricultural sector has by far the world's largest labour force, there are more than one billion workers in this industry worldwide, which contains half of total world force. On other hand, agriculture is most hazardous occupations, and many suffer occupational accidents ill health each year. Farming animal breeding associated with exposure to a wide variety risk factors, including zoonotic agents, dust, elements thermal environment, noise, vibration chemicals. Although...

Toxocariasis is one of the most common zoonotic diseases distributed worldwide. This study aimed to estimate seroprevalence anti-

Background: Albendazole (ABZ) and albendazole sulfoxide (ABZSO) have a basic role in the treatment of hydatid cysts. However, their poor solubility limited intestinal permeability are main problems formulation. Objectives: The preparation characterization ABZ ABZSO-loaded solid lipid nanoparticles (SLNs) to increase cyst membrane permeation by loading into SLNs. Materials Methods: First, SLNs were prepared micro emulsification high shear homogenization. Physicochemical formulations for...

Background: Albendazole (ABZ) and albendazole sulfoxide (ABZSO) have a basic role in the treatment of hydatid cysts. However, their poor solubility limited intestinal permeability are main problems formulation. Objectives: The preparation characterization ABZ ABZSO-loaded solid lipid nanoparticles (SLNs) to increase cyst membrane permeation by loading into SLNs. Materials Methods: First, SLNs were prepared micro emulsification high shear homogenization. Physicochemical formulations for...

Background: Toxoplasmosis is an opportunistic infection caused by Toxoplasma gondii. That asymptomatic in the majority of patients, but it can be life threatening immune-compromised subjects, such as patients with HIV and organ transplant recipients. Objectives: This study aimed to determine Renal Transplant Recipients Ahvaz, South-West Iran. Materials Methods: A total 100 healthy subjects participated this study. The specific IgG IgM antibodies T. gondii were detected two groups ELISA...

The probable association between Toxoplasma gondii (T. gondii) infection and diabetes mellitus (DM) is still controversial, there are several studies with conflicting results. Thus, this study was performed to assess the possible chronic T. type 1 (T1DM) T2DM.In case-control study, a total of 105 diabetic subjects including 36 patients T1DM 69 T2DM were recruited. In addition, 150 nondiabetic enrolled as controls. Each case group had its own control group. participant completed structured...

Background: Obligate intracellular parasites of Leishmania genus belong to the family Trypanosomatidae and more than twenty species cause this neglected vector-borne infection throughout globe. Objective: The current study was aimed assess antileishmanial activity Amphotericin B (AmB) AmB formulated into solid lipid nanoparticles (SLNs) in vitro vivo. Materials Methods: In present research, microemulsification high shear homogenization methods were used prepare SLNs. major (L. major)...

Our study was conducted over the period of two years and explored impact nitrogen fertilization non-fertilization systems on soil health indicators crop yield. hypothesized that no coupled with cover cropping would enhance health, carbon content, bulk density. This found excessive had negative factors such as density increment content decline through deeper profiles. In contrast, no-fertilization system exhibited improved better distribution near surface, suggesting reducing or eliminating...

Treatment of wastewater from synthetic constituents such as methylene blue (MB) which are extensively harmful to environment and human health is known important issue in different industries. Also, implementing experiments solve problems engineering issues highly time consuming costly, so the current work, least square support vector machine (LSSVM) coupled with two evolutionary algorithms particle swarm optimization (PSO) genetic algorithm (GA) predict removal MB on silver nanoparticles....

Abstract Objectives Toxoplasma gondii ( T. ), an obligate intracellular apicomplexan parasite, could affect numerous warm-blooded animals, such as humans. Calcium-dependent protein kinases (CDPKs) are essential Ca 2+ signaling mediators and participate in parasite host cell egress, outer membrane motility, invasion, division. Results Several bioinformatics online servers were employed to analyze predict the important properties of CDPK4 protein. The findings revealed that peptide has 1158...

Apicomplexan parasites, including Toxoplasma gondii (T. gondii), express different types of calcium-dependent protein kinases (CDPKs), which perform a variety functions, attacking and exiting the host cells. In current bioinformatics study, we have used several web servers to predict basic features specifications CDPK7 protein. The findings showed that has 2133 amino acid residues with an average molecular weight (MW) 219085.79 D. aliphatic index 68.78 grand hydropathicity (GRAVY) -0.331...