A5035277747- Acute Myeloid Leukemia Research
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Neutropenia and Cancer Infections
- CNS Lymphoma Diagnosis and Treatment
- Hemoglobinopathies and Related Disorders
- Viral-associated cancers and disorders
- Multiple Myeloma Research and Treatments
- Hematopoietic Stem Cell Transplantation
- Chronic Myeloid Leukemia Treatments
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Platelet Disorders and Treatments
- Cutaneous lymphoproliferative disorders research
- Acute Lymphoblastic Leukemia research
- Kruppel-like factors research
- Hematological disorders and diagnostics
- Blood disorders and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Inflammatory Biomarkers in Disease Prognosis
- Cystic Fibrosis Research Advances
- Liver Disease and Transplantation
- Colorectal and Anal Carcinomas
- Fungal Plant Pathogen Control
Bursa Uludağ Üni̇versi̇tesi̇
2021-2025
Isparta University of Applied Sciences
2022-2024
Nagahama City Hospital
2023
Universidad CES
2023
Sağlık Bilimleri Üniversitesi
2023
Adli Tıp Kurumu
2021
Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disease. Supportive treatments, such as erythropoiesis-stimulating agents (ESAs), are commonly used in patients with low-risk MDS. This study aimed to retrospectively assess the impact of bone marrow Mothers against decapentaplegic homolog 7 (SMAD-7) and Transforming Growth Factor Beta 1 (TGF-β1) protein expression on prognosis response ESA treatment We analyzed diagnosed MDS at adult hematology department Bursa Uludağ...
Abstract The impact of inflammatory markers such as systemic immune-inflammation (SII) index and inflammation response (SIRI) on myelofibrosis (MF) prognosis was evaluated for the first time in this study. Data from 60 patients diagnosed with MF between March 2011 September 2022 were retrospectively analyzed. In addition to disease-related markers, SII SIRI evaluated. our study, overall median survival (OS) 64 months. OS significantly shorter older than 65 years, high ferritin lymphocyte...
Abstract Myelodysplastic syndrome (MDS) is a heterogeneous spectrum of clonal hematopoietic disorders with varying degrees cytopenia and morphologic dysplasia. The hemoglobin, albumin, lymphocyte, platelet (HALP) score prognostic marker in several types malignant tumors. Prognostic value HALP remains unclear for MDS. To determine the baseline We retrospectively analyzed data from 130 newly diagnosed MDS patients evaluated classified under score. By receiver operating characteristic (ROC)...
In this study, we aimed to obtain real-life data on the use of antimyeloma agents, which significantly increase overall survival (OS) in multiple myeloma (MM) patients, primary plasma cell leukemia (pPCL) patients with a poor prognosis.
Introduction: Amphotericin B (AmB-d) is one of the most effective therapeutic options against frequently life-threatening systemic fungal infections in patients with hematologic malignancies. However, significant adverse effects including nephrotoxicity associated its use limit more widespread use. The objectives our study were to determine incidence AmB-d nephrotoxicity, evaluate clinical and epidemiological characteristics patients, support notion that conventional amphotericin remains a...
Infections are the most common cause of anal and perianal pathologies in patients with hematological malignancies. Perianal infection diagnosis this group is difficult; thus, a careful anorectal examination necessary imaging modalities. In addition, literature reveals knowledge gap approach to neutropenia during or chemotherapy. This study aimed examine our institutional data on complications investigate relationship between white blood cell-neutrophil count, lesion, type treatment...
Introduction Chronic infection with Helicobacter pylori (Hp) is an essential cause of gastrointestinal pathologies in adults. Despite being a microorganism proven to play role vitamin B12 deficiency by causing gastric atrophy, Hp's patients non-atrophic gastritis has not been fully explained. Our study investigated whether the presence and density Hp related folate deficiencies gastritis. Methods This retrospective cohort analyzed following parameters, B12, folate, mean red blood cell volume...
Turkish Stem Cell Coordination Center (TURKOK) carries out the procurement process of unrelated allogeneic hematopoietic stem cells in Turkey. This study aims to compare efficacy both once-daily and divided-dose G-CSF administration original biosimilar use frequency severity adverse events TURKOK donors.The was conducted retrospectively with 142 healthy donors. For PBSC mobilization, two different subcutaneous programs were used as 10 μ/kg/day single-dose 5 μ/kg/12 h. Neupogen (Amgen, Puerto...
ABSTRACT In diffuse large B-cell lymphoma (DLBCL), patients needing new alternative regimens in first-line treatment should be selected with better risk classification. After International Prognostic Index (IPI), Revised-IPI (R-IPI), National Comprehensive Cancer Network (NCCN)-IPI, and Grupo Español de Linfomas y Trasplante Autólogo Médula Ósea (GELTAMO)-IPI, have been developed to improve predictions. This study compared performances of four prognostic indices concerning differentiation...
Introduction Multiple myeloma (MM) is a complex plasma cell malignancy characterized by clonal proliferation and monoclonal immunoglobulin production. Despite the availability of several prognostic markers for MM, many are challenging to implement routine clinical practice due cost, complexity, or lack standardization. Red distribution width (RDW), cost-effective routinely measured parameter in complete blood counts, has gained increasing attention as marker its association with disease...
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening occlusive disease of the microcirculation characterized by systemic platelet plugs, organ ischemia, deep thrombocytopenia, and fragmentation erythrocytes. One widely used scoring system to determine clinical probability TTP PLASMIC system. This study aimed evaluate contribution score modifications sensitivity specificity in patients with microangiopathic hemolytic anemia (MAHA) undergoing plasma exchange prediagnosis at our...
Objectives: We aimed to evaluate patients using ibrutinib for the treatment of chronic lymphocytic leukemia (CLL) and relapsed/refractory mantle-cell lymphoma (MCL), focusing on high-risk subgroups, predictors efficacy, response levels, safety profile. Methods: This retrospective cohort study included adult diagnosed with CLL MCL who were started as a single-agent between May 2015 December 2021 in Bursa Uludag University, Department Hematology. Results: Of 45 (23 CLL, 22 MCL) ibrutinib,...
Chronic myeloid leukemia (CML) incidence has recently increased in younger individuals. With time, given the nature of disease and available therapies, as well existing paucity inconsistency advice, worries about fertility have surfaced. all these clear unknowns, we designed this study to raise awareness among both physicians CML patients whether male female childbearing age were using contraception at time diagnosis, if so, which methods they using. In context, aimed evaluate with CML.