A5051271522- Parathyroid Disorders and Treatments
- Thyroid and Parathyroid Surgery
- Medical Imaging and Pathology Studies
- Genetic Syndromes and Imprinting
- Telomeres, Telomerase, and Senescence
- Biomarkers in Disease Mechanisms
- Systemic Sclerosis and Related Diseases
- Cardiovascular and Diving-Related Complications
- Advanced biosensing and bioanalysis techniques
- Cancer-related Molecular Pathways
- Vitamin D Research Studies
- Molecular Biology Techniques and Applications
- Thyroid Disorders and Treatments
- Extracellular vesicles in disease
- Nutritional Studies and Diet
- Mass Spectrometry Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Silk-based biomaterials and applications
- Adrenal Hormones and Disorders
- Climate Change and Health Impacts
- Antimicrobial Peptides and Activities
- Advanced Proteomics Techniques and Applications
- Lipid metabolism and biosynthesis
- Protein Tyrosine Phosphatases
- ATP Synthase and ATPases Research
Augusta University
2024
All India Institute of Medical Sciences
2016-2023
Central Drug Research Institute
2015-2021
All India Institute of Medical Sciences Bhopal
2018
All India Institute of Medical Sciences Raipur
2018
University of Lucknow
2015
We discovered a new class of nontoxic, highly fluorogenic and biocompatible probe AFN for selective staining intracellular Lipid Droplets (LDs) in both fixed live human cervical cancer cells (HeLa) 3T3-L1 pre-adipocytes without any background artifacts. The salient features the are its visible excitation maximum, aqueous compatibility, selectivity remarkable stability (for more than week) cells, even better commercially available Nile red.
Summary Background Cholecalciferol and/or calcium supplementation might increase skeletal muscle strength and serum testosterone in young adult males. Objective We performed a randomized control trial assessing the effect of cholecalciferol/calcium on vitamin D deficient Design Two‐by‐two factorial RCT . Subject Intervention Two‐hundred twenty‐eight males were block‐randomized to (i) double‐placebo, (ii) calcium/placebo, (iii) cholecalciferol/placebo (iv) cholecalciferol/calcium. Doses for...
Western blotting is a widely used analytical technique for detection of specific protein(s) in given sample tissue/cell homogenate or extract. Both chemiluminescence (CL) and colorimetric detections can be imaging blots. Colorimetric substrates offer background free, sensitive, clean results directly on the blotted membrane provides more accurate profile with respect to prestained marker. However, blots stained cannot reused since no stripping protocols have been reported such blots, thus...
There is reservation about accepting the notion of widespread vitamin D deficiency (VDD) in sunny countries because information base largely urban indoors, and cut-off serum 25(OH)D > 75.0 nmol/L to define sufficiency perceived as high.We assessed status subjects engaged six types outdoor jobs with freedom seek shade, when needed.Descriptive observational study.A total 573 outdoors, (hawkers, n = 144; auto-rickshaw drivers, 113; manual rickshaw pullers, 49; fuel-station attendants, 84;...
Abstract Context Basal-ganglia calcification (BGC) is common (70%) in patients with chronic hypoparathyroidism. Interestingly, cortical gray matter spared from calcification. The mechanism of BGC, role hyperphosphatemia, and modulation osteogenic molecules by parathyroid hormone (PTH) its pathogenesis not clear. Objective We assessed the expression a large repertoire proosteogenic or antiosteogenic effects, including neuroprogenitor cells caudate, dentate, normal autopsy tissues. effect high...
The senescence phenotype is heterogeneous, as observed by the context-dependent differential expression of markers. Here, we provide evidence to demonstrate an inverse relationship in pattern two murine variants p21 (p21v1, and p21v2) aging hemorrhagic shock. While upregulation p21v1 was following shock injury, p21v2 upregulated aged mouse. We further show that response is, at least, partially independent p53.
Pathogenesis of idiopathic hypoparathyroidism (IH) is under investigation. Abnormalities in central immune tolerance have yet not been investigated this condition. T-cell receptor excision circles (TRECs) and kappa-deleting recombination (KRECs), formed during gene rearrangements, are tools to assess T- B-cell output.We assessed the number circulating TRECs KRECs patients with IH, autoimmune type 1 diabetes (T1D), thyroiditis (ATs) healthy controls (HCs).Comparative case-control at tertiary...
Basal ganglia calcification (BGC) is a common complication in hypoparathyroid patients, linked to hyperphosphatemia and altered vitamin-D calcium homeostasis following conventional therapy. The pathogenesis of BGC hypoparathyroidism not clear. Recently, we developed an ex vivo model using rat-striatal cell culture 10.0 mmol/L β-glycerophosphate (31.8 mg/dL phosphate). However, the effect 1,25(OH) 2 D, calcium, milder phosphate excess on known. This study describes two modified models...
Antimicrobial-peptides are important molecules of constitutive innate immunity. Though patients with diabetes mellitus generally prone to infections, there is limited information on their antimicrobialpeptide status. We assessed the circulating LL-37 antimicrobial peptide (also referred as cathelicidin) levels in type 1 and its relation glycemic The mRNA expression was peripheral blood mononuclear cells (PBMC) by quantitative RT-PCR usingβ- actin cytochrome-C1 reference genes 154 subjects...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Kumar Agnihotri S, Kar P, Singh M, et al. Modulation of protein phosphatase 1 gamma 2 during cell division cervical cancer HeLa cells. Contemporary Oncology/WspóÅczesna Onkologia. 2021;25(2):125-132. doi:10.5114/wo.2021.107745. APA Agnihotri, S., Kar, P., Singh, M., Pant, G., Mitra, K., & Lal Brahma Bhatt, M. (2021). Onkologia, 25(2), 125-132. https://doi.org/10.5114/wo.2021.107745 Chicago Saurabh, Parmita...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)