A5046919110- Poisoning and overdose treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Neurotransmitter Receptor Influence on Behavior
- Chemotherapy-induced cardiotoxicity and mitigation
- Alcoholism and Thiamine Deficiency
- Neonatal Health and Biochemistry
- Cannabis and Cannabinoid Research
- Cancer Treatment and Pharmacology
- Public health and occupational medicine
- Nicotinic Acetylcholine Receptors Study
- Cancer, Hypoxia, and Metabolism
- Cardiac electrophysiology and arrhythmias
- Renal function and acid-base balance
- ECG Monitoring and Analysis
- Neuroscience and Neuropharmacology Research
- Nutrition and Health Studies
- Bipolar Disorder and Treatment
- Pharmacological Effects of Natural Compounds
- Biochemical effects in animals
- Electrolyte and hormonal disorders
- Takotsubo Cardiomyopathy and Associated Phenomena
- Electroconvulsive Therapy Studies
- Peptidase Inhibition and Analysis
- Pesticide Exposure and Toxicity
- Plant-based Medicinal Research
Medical University of Lublin
2017-2025
Cardinal Stefan Wyszyński University in Warsaw
2025
1 Military Clinical Hospital with Outpatient Clinic
2021-2024
Wojewódzki Szpital Zespolony
1997-2013
The objective of this study was to assess the antidepressant efficacy a novel imipramine–magnesium (IMI–Mg) complex in comparison administration imipramine and magnesium individually. utilized adult male albino Swiss mice. Behavioral assessments were conducted using forced swim test (FST) tail suspension (TST). A locomotor activity exclude false positive results FST TST. Moreover, assessed oxidative stress levels mice subjected acute environmental by measuring glutathione peroxidase,...
Introduction Severe carbon monoxide may impact the circulatory system, potentially leading to myocardial injury. This study aimed assess left ventricular function via echocardiography in patients with acute poisoning who were otherwise healthy.
Late cardiotoxicity is a formidable challenge in anthracycline-based anticancer treatments. Previous research hypothesized that co-administration of carvedilol (CVD) and dexrazoxane (DEX) might provide superior protection against doxorubicin (DOX)-induced compared to DEX alone. However, the anticipated benefits were not substantiated by findings. This study focuses on investigating impact CVD myocardial redox system parameters rats treated with DOX + DEX, examining its influence overall...
Biodegradable materials are used in the manufacture of packaging and compostable films various types medical products. These have demonstrated high potential applications: cardiac, vascular orthopaedic conditions adults as well children. In our research, extrusion-cooking technique was to obtain environmentally friendly loose-fill foams packaging. Potato starch basic raw material. Polyvinyl alcohol an additive amount 1%, 2% 3% replace starch. The components were mixed moistened with water...
Copper is an essential element to brain cells as it a cofactor and structural component of various enzymes involved in energy metabolism pathways. Accumulating evidence points the pivotal role copper deficiency neurodegeneration resulting from impaired homeostasis. Despite indisputable mitochondrial respiration, its homeostasis regulation tissue remains unclear. The assessment changes expression genes encoding key pathways can greatly benefit further studies exploring copper’s...
The purpose of this study was to determine the effect addition fresh kale and processing conditions on extruded pellet antioxidant activity selected physicochemical properties. results applied DPPH, FRAP, TPC methods indicated that, for both 60 100 rpm screw speeds, snack phenolic content were strongly linked content, these properties increased with plant. amount variables (extruder speed moisture raw material blends) also found significantly affect water absorption index, solubility fat...
Although a lot of information can be found on the specific dual role endocannabinoid system in emotional-related responses, little is known whether stimulation or inhibition cannabinoid (CB) receptors may affect activity frequently prescribed antidepressant drugs. Our interests have been particularly focused potential influence CB2 receptors, as ones whose central effects are relatively poorly documented when compared to CB1 receptors. Therefore, we evaluated interaction between receptor...
A new type of multigrain snack has been designed containing varied additions Moldavian dragonhead (Dracocephalum moldavica L.) seeds. The antioxidant properties and the general health benefits this plant material have already widely acknowledged. research discussed herein aimed to investigate influence formulation expansion method (frying) on content polyphenolic compounds, individual phenolic acids, antiradical innovative snacks enriched with highest polyphenols (0.685 mg GAE/mL), free...
As new sources of proteins, edible insects may be excellent additives in a generation environmentally friendly food products that are nutritionally valuable, safe, sustainable, and needed today's world. The aim this study was to determine the effect application cricket flour on extruded wheat-corn-based snack pellets' basic composition, fatty acids profile, nutritional value, antioxidant activity selected physicochemical properties. Results showed had significant impact composition...
The anticancer efficacy of doxorubicin (DOX) is dose-limited because cardiomyopathy, the most significant adverse effect. Initially, cardiotoxicity develops clinically silently, but it eventually appears as dilated cardiomyopathy with a very poor prognosis. Dexrazoxane (DEX) only FDA-approved drug to prevent development anthracycline its insufficient. Carvedilol (CVD) another product being tested in clinical trials for same indication. This study's objective was evaluate rats treated CVD...
Abstract Background Though there are several classes of antidepressant drugs available on the pharmaceutical market, depression that affects globally over 320 million people is still undertreated. Scientists have made attempts to develop novel therapeutical strategies maximize effectiveness therapy and minimize undesired reactions. One ideas use either dual-action agents or combined administration two substances affect diverse neurotransmissions. Thus, we investigated whether selected CB...
The main goal of this study was to determine the antidepressant-like potential co-administration sodium selenite (Se) and selective adenosine A1 A2A antagonists DPCPX istradefylline (IST), respectively, in mice despair tests. Biochemical studies were performed elucidate action mechanisms investigated treatment strategies. results confirmed that, when administered by itself, Se exerts an effect FST TST that activity is dose-dependent. Further experiments demonstrated (0.25 mg/kg)...
The impact of the amount durum wheat bran additive used on selected structural, mechanical, and spectroscopic properties thermoplastic starch moldings was examined in this study. Bran added to corn from 10 60% by weight blends. Four temperature settings were for high-pressure injection: 120, 140, 160, 180 °C. highest value elongation at break (8.53%) observed containing bran. Moreover, these moldings, tensile strength flexural lower (appropriately 3.43 MPa 27.14 MPa). deformation (1.56%)...
Clinical manifestation of organophosphates toxicity may be differentiate and include cholinergic toxidrome, intermediate syndrome, OP-induced delayed polyneuropathy to chronic neuropsychiatric disorder (OPIDN). Patients symptoms, along with decrease in cholinesterase serum level, determines the possible diagnosis organophosphate poisoning.The aim study was present clinical level changes intoxication organophosphorus compounds patients.A data base created by analysis hospital documents 34...
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