Bing Fu

ORCID: 0000-0001-9952-2244
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About
Contact & Profiles
Research Areas
  • Bacterial Genetics and Biotechnology
  • Advanced biosensing and bioanalysis techniques
  • MicroRNA in disease regulation
  • Microbial Community Ecology and Physiology
  • Microplastics and Plastic Pollution
  • Meat and Animal Product Quality
  • Gold and Silver Nanoparticles Synthesis and Applications
  • biodegradable polymer synthesis and properties
  • Nanowire Synthesis and Applications
  • Metabolomics and Mass Spectrometry Studies
  • Bacterial biofilms and quorum sensing
  • Coastal wetland ecosystem dynamics
  • Recycling and Waste Management Techniques
  • Plasmonic and Surface Plasmon Research
  • Plant Molecular Biology Research
  • Bacteriophages and microbial interactions
  • Animal Genetics and Reproduction
  • Plant nutrient uptake and metabolism
  • Advanced Chemical Sensor Technologies
  • Aquaculture disease management and microbiota
  • Reproductive biology and impacts on aquatic species
  • Marine Biology and Environmental Chemistry
  • Epigenetics and DNA Methylation
  • Legume Nitrogen Fixing Symbiosis
  • Thermal properties of materials

South China Agricultural University
2022-2025

Cornell University
2019-2025

The First People’s Hospital of Lianyungang
2024

Xian Yang Central Hospital
2024

Nanchang University
2015-2023

Chinese Academy of Fishery Sciences
2021-2023

Fuzhou University
2021-2023

Nankai University
2018

University of Michigan
2013-2017

Shanghai Normal University
2015-2016

Coupling to metal nanoparticles can increase the fluorescence intensity and photostability of fluorescent probes, this plasmon-enhanced is particularly promising for dimmer proteins common in biological imaging. Here, we measure distribution single Cy3.5 dye molecules mCherry one at a time as they adsorb on conformal surface 4.8–61.0 nm thick over gold nanorod (NR). The emission intensities both types fluorophores depend nonmonotonically spacer thickness, an optimal thickness ∼10 observed...

10.1021/acs.jpcc.5b05154 article EN The Journal of Physical Chemistry C 2015-07-23

Microplastics (MPs) are 1-5 mm plastic particles that serious global contaminants distributed throughout marine ecosystems. However, their impact on intertidal sediment microbial communities is poorly understood. In this study, we conducted a 30-day laboratory tidal microcosm experiment to investigate the effects of MPs communities. Specifically, used biodegradable polymers polylactic acid (PLA) and polybutylene succinate (PBS), as well conventional polyethylene terephthalate (PET),...

10.1016/j.jhazmat.2023.131813 article EN cc-by-nc Journal of Hazardous Materials 2023-06-09

Multidrug efflux pumps confer not only antibiotic resistance to bacteria but also cell proliferation. In gram-negative bacteria, the ATP-binding cassette (ABC)-family transporter MacB, adaptor protein MacA, and outer membrane TolC form MacA6:MacB2:TolC3 assembly extrude antibiotics virulence factors. Here, using quantitative single-molecule single-cell imaging, we uncover that, in E. coli cells, there is a large excess of MacB (and TolC) driving limiting MacA mostly into MacAB-TolC assembly....

10.1016/j.xcrp.2025.102441 article EN cc-by-nc-nd Cell Reports Physical Science 2025-02-01

Integrating the optoelectronic properties of quantum dots (QDs) with biological enzymatic systems to form microbe-semiconductor biohybrids offers promising prospects for both solar-to-chemical conversion and light-modulated biochemical processes. Developing these nano–bio hybrid necessitates a deep understanding charge-transfer dynamics at interface. Photoexcited carrier transfer from QDs microbes is driven by complex interactions, emerging insights into relevant thermodynamic kinetic...

10.1073/pnas.2407987122 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2025-03-17

Urbanization carries essential influences to ecosystem of soil bacteria in coastal cities. Comprehending the patterns and drivers bacterial diversity are understanding how ecosystems respond environmental change. This study aimed explore community (SBC) response distinct urbanization cities on composition, assembly process potential function Guangdong province, south China. 72 samples from 24 sample sites within 3 were included study. Soil chemical properties analyzed, investigated by...

10.1016/j.ecoenv.2022.114492 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2023-01-01

Plasmonic nanoparticles (NPs) enhance the radiative decay rate of adjacent dyes and can significantly increase fluorescence intensity for improved spectroscopy. However, NP nanoantenna complicates super-resolution imaging by introducing a mislocalization between emitter position its super-resolved emission position. The magnitude depends strongly on dye/NP coupling geometry. It is therefore crucial to quantify recover actual in coupled system. Here, we super-resolve two three dimensions...

10.1021/acsnano.7b03420 article EN ACS Nano 2017-08-15

Significance The field of mechanobiology examines how physical forces modulate cell physiology and has traditionally focused on eukaryotic organisms. Here we show that in bacteria, mechanical stresses can interrupt the structure function a molecular assembly used by Gram-negative bacteria to survive grow presence toxins. This work provides evidence like mammalian cells, respond through complexes at surface ways are relevant growth. Our observations further suggest may be synergistically with...

10.1073/pnas.1909562116 article EN Proceedings of the National Academy of Sciences 2019-11-26

Heat stress has received growing concerns regarding the impact on seafood quality. However, effects of heat sensory properties remain unknown. In this study, fresh oyster (Crassostrea ariakensis) treated with chronic (30 °C) for 8 weeks were characterized using electronic nose, tongue, evaluation, HS–SPME–GC–MS, LC–MS and transcriptomics. Overall, reduced overall oysters. The metabolic network constructed. based enrichment results 423 differential metabolites 166 differentially expressed...

10.3390/foods13132004 article EN cc-by Foods 2024-06-25

Metal detoxification is essential for bacteria’s survival in adverse environments and their pathogenesis hosts. Understanding the underlying mechanisms crucial devising antibacterial treatments. In Gram-negative bacterium Escherichia coli , membrane-bound sensor CusS its response regulator CusR together regulate transcription of cus operon that plays important roles cells’ resistance to copper/silver, they belong two-component systems (TCSs) are ubiquitous across various organisms diverse...

10.1073/pnas.1919816117 article EN Proceedings of the National Academy of Sciences 2020-05-28

Understanding the metabolic and transcription basis of pumpkin seed oil (PSO) intervention on disease (MD) is essential to daily nutrition health.This study analyzed liver variations Wistar rats fed normal diet (CON), high-fat (HFD) plus PSO establish relationship between metabolite composition/transcript profile effects MD. By using proton nuclear magnetic resonance spectroscopy together with multivariate data analysis, it was found that, compared CON rats, HFD showed clear dysfunctions...

10.1002/jsfa.7842 article EN Journal of the Science of Food and Agriculture 2016-06-13

10.1007/s11051-015-3160-9 article EN Journal of Nanoparticle Research 2015-09-01

Summary Microbial phylogenetic diversity and species interactions in natural ecosystems have been investigated extensively, but our knowledge about their ecological roles, community dynamics succession patterns is far from complete. This essential to understand the complicated of microorganisms ecosystems. Here, an artificial ecosystem model was constructed oil‐well products cultivated a chemostat investigate pattern alkane‐degrading bacteria, functional population oil reservoirs. Their...

10.1111/1462-2920.14382 article EN Environmental Microbiology 2018-08-17

A new insulin-like growth factor (Igf) subtype 3 (igf3) has recently been found in the bony fish orange-spotted grouper (Epinephelus coioides). However, role of igf3 maturation ovary and sex differentiation E. coioides is currently unknown. We examined ovarian localization receptor binding novel ortholog Igf3 using qRT-PCR, Western blotting, combined with situ hybridization immunohistochemistry methods. Results demonstrated presence mRNA protein mature oocytes. Furthermore, expression was...

10.3390/ijms24032868 article EN International Journal of Molecular Sciences 2023-02-02
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