A5027666478- Intraperitoneal and Appendiceal Malignancies
- Trace Elements in Health
- Appendicitis Diagnosis and Management
- Iron Metabolism and Disorders
- Heavy Metal Exposure and Toxicity
- Healthcare professionals’ stress and burnout
- Diversity and Career in Medicine
- Ovarian cancer diagnosis and treatment
- Innovations in Medical Education
- Breast Lesions and Carcinomas
- Sarcoma Diagnosis and Treatment
- Traumatic Ocular and Foreign Body Injuries
- Omental and Epiploic Conditions
- Vascular Procedures and Complications
- Sarcoidosis and Beryllium Toxicity Research
- Hemoglobinopathies and Related Disorders
- BRCA gene mutations in cancer
- Bariatric Surgery and Outcomes
- Diverticular Disease and Complications
- Uterine Myomas and Treatments
- Histiocytic Disorders and Treatments
- Breast Cancer Treatment Studies
- IgG4-Related and Inflammatory Diseases
- Hernia repair and management
- Vascular Anomalies and Treatments
Virginia Commonwealth University
2023-2024
Saint Louis University
2024
Children's Hospital of Richmond at VCU
2024
University of Cincinnati
2007-2024
Carl R. Darnall Army Medical Center
2021
University of Mississippi Medical Center
2016-2018
Jackson Memorial Hospital
2016
University of Cincinnati Medical Center
2009-2012
Recent studies have shown that overexpression of the transmembrane protein Zrt- and Irt-like 14 (Zip14) stimulates cellular uptake zinc nontransferrin-bound iron (NTBI). Here, we directly tested hypothesis Zip14 transports free zinc, iron, other metal ions by using Xenopus laevis oocyte heterologous expression system, use this approach also allowed us to characterize functional properties Zip14. Expression mouse in RNA-injected oocytes stimulated (55)Fe presence l-ascorbate but not...
Diagnosis of ductal carcinoma in situ (DCIS) represents about 25% newly diagnosed breast cancers. There is debate the benefit sentinel lymph node biopsy (SLNB) for further staging and guidance therapy patients with DCIS. Current guidelines recommend SLNB undergoing breast-conserving (BCT) Utilizing superparamagnetic iron oxide (SPIO) nanoparticles as a tracer may allow delayed (d-SLNB), typically within month injection. We present our experience patient who due to complications from surgery...
Successful leaders influence the group they represent. Effective surgical care is tied to its leadership climate. However, most providers are not attuned their individual strengths which if known could leverage them within teams. This study identifies types a department of surgery may be used better understand and cultivate strengths.
Open cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a therapeutic option for the management of malignancies peritoneal carcinomatosis and origin. Robotic shows promise as minimally invasive approach select patients. We aimed to evaluate differences in outcomes between robotic versus open CRS/HIPEC hypothesized less morbidity faster recovery group.
Appendiceal cancer treatment may include cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC). We investigated whether patient race/ethnicity influences outcomes overall survival for patients with appendiceal who undergo CRS/HIPEC. queried the National Cancer Database adult treated CRS/HIPEC from 2006 to 2018. Patients were stratified by race/ethnicity: non-Hispanic White (NHW), Black (NHB), Hispanic, Other. Sociodemographics compared using descriptive statistics....
Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare tumor of soft tissue. It typically presents as low-grade with myxoid stroma, has predilection for distal extremities, and displays high propensity local recurrence, but low metastatic potential. The risk factors associated high-risk lesions metastasizing are poorly defined. In cases where the metastasizes, therapeutic options few, death rare. Our case discusses an aggressive MIFS that progressed from painless lesion on patient's calf, to...
Provider burnout is a work-related syndrome that under-recognized, under-reported, and has negative repercussions on the individual, system, patients. This study investigated incidence its association with wellness characteristics such as resilience, psychological safety, perceptions of workplace to inform future work in improving well-being.
•Metastatic disease to the small bowel may present with intussusception.•Clinical decision making for malignant obstruction is difficult and individual specific.•Malignant due metastatic year has an average life expectancy of less than 200 days.
Perforated ulcers of the gastric remnant and duodenum seem to be a rare complication after Roux-en-Y bypass. Diagnosis this can difficult given vague presentation, however, early intervention is critical prevent further morbidity. We present case 38-year-old male with perforated duodenal ulcer nearly year Upon he complained 8 hours epigastric pain. His medical history was significant for chronic peptic disease negative H. pylori. Recently, had been prescribed naproxen by his primary care...
We have previously demonstrated that Zip14, a member of the ZIP family metal‐ion transport proteins, can zinc and iron into cells. The aim present study was to investigate metal transport, subcellular localization, tissue distribution Zip8, most closely related protein Zip14. Similar we found transient transfection HEK 293T cells with Zip8 cDNA enhanced cellular uptake zinc, is detectable at cell surface as transmembrane glycoprotein. Expression in RNA‐injected Xenopus oocytes stimulated...
Iron‐overload conditions (e.g., thalassemia, hereditary hemochromatosis) are characterized by the appearance in plasma of nontransferrin‐bound iron (NTBI), and result cardiomyopathy, diabetes, hepatic cancer cirrhosis. Since zinc transporter ZIP14 (SLC39A14) is strongly expressed liver, heart, pancreas‐major sites organ damage overload‐we tested hypothesis that transports free iron. We murine Xenopus oocytes examined its activity using radiotracer assays voltage clamp. stimulated uptake 55...
Background: Appendicitis is a common condition affecting 7-8% of the general population. With improvement noninvasive imaging, diagnostic approach and treatment algorithm for patients with clear signs symptoms suggestive acute appendicitis are well agreed-upon. However, without pathognomonic symptoms, but equivocal imaging pose dilemma. These may still have could potentially benefit from laparoscopic appendectomy. This be especially true in subset appendicoliths.Methods: Our case series...
The authors describe an equipment list for ultramobile, surgeon-carried set that is specifically designed missions require the extremes of constraints on personnel and resources conducted outside ring golden hour access to damage control surgery (DCS) capabilities.