A5079546800- Aging, Elder Care, and Social Issues
- Dementia and Cognitive Impairment Research
- Health, Medicine and Society
- Peripheral Artery Disease Management
- Epilepsy research and treatment
- Acute Ischemic Stroke Management
- Parasites and Host Interactions
- Nutrition and Health in Aging
- Migration, Identity, and Health
- Health disparities and outcomes
- Blood Pressure and Hypertension Studies
- Nutritional Studies and Diet
- Health and Well-being Studies
- Child Nutrition and Water Access
- Healthcare Systems and Practices
- Trypanosoma species research and implications
- Health Systems, Economic Evaluations, Quality of Life
- Mental Health Treatment and Access
- Pharmacological Effects and Toxicity Studies
- Alzheimer's disease research and treatments
- Chronic Disease Management Strategies
- Retinal Imaging and Analysis
- Parasitic Diseases Research and Treatment
- HIV/AIDS Research and Interventions
- Cerebrovascular and Carotid Artery Diseases
University of Bangui
2015-2024
Inserm
2010-2023
Institut d’Epidémiologie Neurologique et de Neurologie Tropicale
2013-2023
Institut de Recherche pour le Développement
2020-2023
Institut d’Epidémiologie et de Neurologie Tropicale
2010-2022
Université de Limoges
2012-2021
Centre National de la Recherche Scientifique
2012-2020
Centre Hospitalier et Universitaire de Brazzaville
2010-2019
Amitie
1997-2019
Université d'Abomey-Calavi
2010
Abstract Background Subjective cognitive decline (SCD) is recognized as a risk stage for Alzheimer’s disease (AD) and other dementias, but its prevalence not well known. We aimed to use uniform criteria better estimate SCD across international cohorts. Methods combined individual participant data 16 cohorts from 15 countries (members of the COSMIC consortium) used qualitative quantitative (Item Response Theory/IRT) harmonization techniques prevalence. Results The sample comprised 39,387...
<i>Background:</i> Data on dementia from low- and middle-income countries are still necessary to quantify the burden of this condition. This multicenter cross-sectional study aimed at estimating prevalence in 2 large cities Central Africa. <i>Methods:</i> General population door-to-door surveys were conducted districts Bangui (Republic Africa) Brazzaville (Congo) elderly aged ≧65 years. The subjects screened with Community Screening Interview for Dementia Five-Words...
The worldwide population is ageing and the proportion of elderly aged 60 over expected to dramatically rise in Low Middle Income Countries (LMIC). epidemic dementia will not spare those countries, where largest increases numbers people affected are estimated. Besides, still understudied sub-Saharan Africa (SSA) compared other regions. This paper describes protocol for 'Epidemiology Dementia Central Africa' population-based study, which aims at estimating prevalence two countries...
The simultaneous emergence of human immunodeficiency virus (HIV)-1 group M and HIV-2 into populations, circa 1921-1940, is attributed to urbanization changes in sexual behavior. We hypothesized that the initial dissemination HIV-1, before transmission predominated, was facilitated by administration, via reusable syringes needles, parenteral drugs against tropical diseases. As proxies for highly lethal we investigated risk factors hepatitis C (HCV) T cell lymphotropic 1 (HTLV-1) infections,...
Risk factors for dementia in American and European countries have been well investigated. However, little research has carried out sub-Saharan Africa, where life events as environmental, socio-economic, modifiable risk (i.
The molecular epidemiology of hepatitis C virus (HCV) in the Central African Republic (CAR) is poorly documented. Thus, we conducted phylogenetic analyses NS5B gene sequences from 58 HCV-infected inhabitants a remote area south-west CAR, which indicated that 48 (82.8%) were infected with genotype 4 (HCV-4), five (8.6%) 2 and 1. HCV-4 strains highly heterogeneous, containing previously described subtypes 4k (48%), 4c (27%), 4r (4%), 4f (4%) unclassified (17%). To estimate epidemic history...
Dementia will concern more and people in the developing countries, but perception have of dementia these areas has not yet been studied.During a general population survey (EDAC) carried out Brazzaville (Republic Congo), 27 elderly persons suspected having 31 their relatives, 90 cognitively impaired 92 as well 33 hospital workers were interviewed according to Explanatory Model Interview Catalogue.Item prominence ratings indicate that attention was mainly on emotional socio-economic...
Several studies in Western countries have shown an association between cognitive disorders and low BMI or weight loss elderly people. However, few data are available Africa. We analysed the undernutrition among people Central A cross-sectional, multicentre, population-based study using a two-phase design was carried out subjects aged 65 years above African Republic (CAR) of Congo (ROC). All were interviewed Community Screening Interview for Dementia, those with performance clinically...
The rate of virological failure was assessed in 386 adult patients attending the Centre National Hospitalier Universitaire Bangui, capital city Central African Republic (CAR), receiving their first-line antiretroviral (ARV) drug regimen for 24 months, according to World Health Organization (WHO) recommendations. In addition, genotypic resistance testing carried out 45 145 randomly selected whose plasma HIV-1 RNA load detectable. Overall, 28.5% ARV-treated were (e.g., >3.7 log(10) copies/ml)....
Western research into dementia has focused on finding effective means of prevention, particularly through nutrition. To date, however, little is known about the relationship between diet and cognitive disorders in Africa, where number people with expected to increase most over coming decades. The objective study was investigate alcohol intake among elderly Central Africa. Between 2011 2012, a cross-sectional multicentre population-based carried out rural urban areas African Republic (CAR)...
<b><i>Background/Aims:</i></b> Dementia is an emerging public health problem in sub-Saharan Africa (SSA). In SSA, the stigma suffered by people with dementia (PWD) can be strongly linked to pejorative social representations, interfering relationships informal caregivers. The objective of study was analyze consequences representations PWD interactions <b><i>Methods:</i></b> A qualitative conducted Republic Congo among 93 interviewees....
Objectives To investigate the association between peripheral arterial disease ( PAD ) and dementia in native elderly African populations. Design Two successive door‐to‐door cross‐sectional surveys general population. Settings Representative districts of Bangui (Central Republic) Brazzaville (Republic Congo). Participants Population aged 65 older. Measurements Peripheral was defined as an ankle–brachial index ABI 0.90 or less. Cognitive screening performed using Community Screening Interview...
ABSTRACT Human African trypanosomiasis (HAT) or sleeping sickness is a disease characterized by hemolymphatic stage 1 followed meningoencephalitic 2 which fatal without specific treatment. Furthermore, due to the toxicity of drugs used treat (mainly melarsoprol) accurate staging required. Actual criteria employed during field surveys are not sensitive enough for precise staging. Antineurofilament (anti-NF) and antigalactocerebrosides (anti-GalC) antibodies have been identified in...
We aimed at estimating the seroprevalence of Toxoplasma gondii (T. gondii) infection in older adults living Central Africa and investigating its association with dementia using data from Epidemiology Dementia (EPIDEMCA) programme.A cross-sectional multicentre population-based study was carried out among participants aged 73 (±7) years on average, rural urban areas African Republic Congo between November 2011 December 2012. Blood samples were collected each consenting participant. The...
ABSTRACT Background: To date, no studies have examined the relationship between cognitive disorders and personality disorders. Our aim was to investigate association dependent disorder (DPD) in Central Africa. Methods: Between 2011 2012, a cross-sectional multicenter population-based study carried out rural urban areas of African Republic (CAR) Congo (ROC). Participants aged ≥65 years were interviewed using Community Screening Interview for Dementia (CSI-D). Elderly people who performed...
The term Nodding Syndrome (NS) refers to an atypical and severe form of childhood epilepsy characterized by a repetitive head nodding (HN). disease has been for long time limited East Africa, the cause is still unknown. objective this study was confirm existence NS cases in Central African Republic (CAR).This cross-sectional descriptive general population. identification conducted through door-to-door survey village near Bangui along Ubangui River. Based on Winkler's 2008 World Health...