A5006739416- Parasite Biology and Host Interactions
- Parasites and Host Interactions
- Helminth infection and control
- Trace Elements in Health
- Virus-based gene therapy research
- Acute Myeloid Leukemia Research
- Liver Disease Diagnosis and Treatment
- Polyomavirus and related diseases
- RNA Research and Splicing
- Multiple Myeloma Research and Treatments
- Hematopoietic Stem Cell Transplantation
- Retinoids in leukemia and cellular processes
- Immune Cell Function and Interaction
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Natural Antidiabetic Agents Studies
- Cell Adhesion Molecules Research
- Calcium signaling and nucleotide metabolism
- Global Cancer Incidence and Screening
- Ion Transport and Channel Regulation
- Viral Infections and Immunology Research
- CAR-T cell therapy research
- Diet, Metabolism, and Disease
- Parasitic infections in humans and animals
- HER2/EGFR in Cancer Research
- Immunotherapy and Immune Responses
University of Pennsylvania
2015-2022
Shyam Shah Medical College
2016
University of Florida
2011-2016
University of Florida Health
2010
Epstein-Barr virus (EBV) SM protein is an essential nuclear produced during the lytic cycle of EBV replication. RNA-binding with multiple mechanisms action. enhances expression genes by stabilizing mRNA and facilitating export. also influences splicing both cellular pre-mRNAs. modulates splice site selection host cell STAT1 pre-mRNA, directing utilization a novel 5' that used only in presence SM. activates manner SR proteins but does not contain canonical RS domains typical factors. Affinity...
Hematological malignancies such as leukemias, lymphomas, multiple myeloma (MM), and the myelodysplastic syndromes (MDSs) primarily affect adults are difficult to treat. For high-risk disease, hematopoietic stem cell transplant (HCT) can be used. However, in setting of autologous HCT, relapse due contamination autograft with cancer cells remains a major challenge. Ex vivo manipulations purge using chemotherapies toxins have been attempted. Because these past strategies lack specificity for...
Parasitic helminths such as schistosomes, well filarial and soil-transmitted nematodes, are estimated to infect at least a billion people worldwide, with devastating impacts on human health economic development. Diagnosis monitoring of infection dynamics efficacy treatment depend almost entirely methods that inaccurate, labor-intensive, unreliable. These shortcomings amplified take added significance in mass drug administration programs, where measures effectiveness accurate success (or...
Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease estimated to affect over 200 million people worldwide. Praziquantel is only antischistosomal currently available for treatment, and there an urgent need new therapeutics. Ion channels play key roles in physiology are targets many anthelmintics, yet few representatives have been characterized any detail schistosomes other parasitic helminths. The transient receptor potential (TRP) channel...
Background: Cancer is on rise. WHO estimates that by 2030, the incidence of cancer will increase 68% as compared to 2012. This study evaluates epidemiological profile in Vindhya region. Design this was combination retrospective and prospective study.Methods: All patients admitted surgery ward S. medical college, Rewa between 2010 2014 were included study. Data regarding age, gender, religion, socio-economic status, residence, dietary habits, addiction site well mortality pattern tabulate,...
6611 Background: Several small molecule tyrosine kinase inhibitors targeting angiogenesis have been approved for the treatment of solid tumors. In patients with leukemia, upregulated portends a worse prognosis and leukemia cells are known to express receptors angiogenic cytokines. Therefore, we hypothesized that inhibiting on leads disease regression. Methods: Human acute myeloid (AML) (HL-60) were treated anti-angiogenic agent, pazopanib, alone in combination cytarabine. Cell proliferation...