A5027868763- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive biology and impacts on aquatic species
- Marine Biology and Environmental Chemistry
- Organometallic Compounds Synthesis and Characterization
- Drug Transport and Resistance Mechanisms
- Protein Kinase Regulation and GTPase Signaling
- Retinoids in leukemia and cellular processes
- Crop Yield and Soil Fertility
- Plant Genetic and Mutation Studies
- Dyeing and Modifying Textile Fibers
- Metal complexes synthesis and properties
- Dye analysis and toxicity
- RNA Research and Splicing
- Computational Drug Discovery Methods
- Animal Genetics and Reproduction
- Neurobiology and Insect Physiology Research
- Hippo pathway signaling and YAP/TAZ
- Cancer-related molecular mechanisms research
- Peroxisome Proliferator-Activated Receptors
- Pharmacogenetics and Drug Metabolism
- Seed Germination and Physiology
Chinese Academy of Fishery Sciences
2023-2024
Dalian Ocean University
2024
Zhongkai University of Agriculture and Engineering
2023
Shanxi Medical University
2018-2019
Waxy corn has a short growth cycle and high multiple cropping index. However, after being planted in early spring, late autumn winter, it is susceptible to low temperature (LT), which reduces the emergence rate yield. Therefore, important analyze response mechanism of waxy under LT stress.All phenotype indexes inbred lines N28 were significantly higher than N67 LT. With increase stress time, all physiological showed an upward trend N67. Differentially expressed genes (DEGs) 16,017 14,435...
Dibutyltin dilaurate (DBTD) has multiple applications in daily life. However, DBTD is easily deposited the liver and affects functions. This study was designed to explore effects of on triglyceride metabolism human normal hepatocyte HL7702 cells. Our results showed that intracellular fat contents were dose-dependently decreased by DBTD. The expression lipolysis genes proteins elevated while lipogenesis diminished phosphorylation levels ribosomal S6 kinase 1 reduced both rapamycin DBTD,...
Abstract Organotin anticancer agent di-n-butyl-di-(4-chlorobenzohydroxamato)tin(iv) (DBDCT) exerted an inhibitory effect on its major metabolic enzyme cytochrome CYP3A. But whether hepatic drug-metabolizing enzymes and their regulatory nuclear receptors including pregnane PXR constitutive androstane CAR binding with retinoid receptor RXR as a heterodimer are involved in the DBDCT-mediated regulation of CYP3A remains unclear. This study was undertaken to determine mechanisms responsible for...
The sex chromosome, especially specific in one sex, generally determines sexual size dimorphism (SSD), a phenomenon with dimorphic difference the body size. For Cynoglossus semilaevis, flatfish China, although importance of chromosome W and its gene zbed1 female-biased SSD have been suggested, family members regulation information are still unknown. At present, three copies were identified on W, no gametologs. Phylogenetic analysis for ZBED revealed an existence ZBED9 fish. Nine uncovered...
Diorganotin(IV) antitumor compound bis-[2,6-difluoro- N -(hydroxyl-<κ> O )benzamidato-<κ> ] (DBDF2,6T) was one of the novel patent organotin compounds with high activity and relatively low toxicity. In this study, several methods were used to study interaction between DBDF2,6T hPPAR γ protein, including fluorescence quenching, three-dimensional (3D) fluorescence, drug affinity responsive target stability (DARTS), ultrafiltration-LC, molecular docking. According experimental...