Ajay Sharma

ORCID: 0000-0002-0078-4322
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Cutaneous Melanoma Detection and Management
  • Nonmelanoma Skin Cancer Studies
  • Dermatologic Treatments and Research
  • Hair Growth and Disorders
  • Early Childhood Education and Development
  • Nail Diseases and Treatments
  • Drug-Induced Adverse Reactions
  • Skin Protection and Aging
  • Cutaneous lymphoproliferative disorders research
  • Child Nutrition and Feeding Issues
  • Microscopic Colitis
  • Child and Adolescent Health
  • Oral microbiology and periodontitis research
  • Social Policy and Reform Studies
  • Viral Infections and Vectors
  • Cancer and Skin Lesions
  • Urticaria and Related Conditions
  • Educational and Psychological Assessments
  • Infant Development and Preterm Care
  • Mast cells and histamine
  • Facial Rejuvenation and Surgery Techniques
  • Autoimmune Bullous Skin Diseases
  • Acne and Rosacea Treatments and Effects
  • Animal Disease Management and Epidemiology
  • Antibiotic Use and Resistance

University of California, Irvine
2018-2025

Texas Tech University
2025

Texas Tech University Health Sciences Center
2025

Wright State University
2025

JSS Medical College and Hospital
2024

JSS Academy of Higher Education and Research
2024

University of California, Irvine Medical Center
2020-2024

UC Irvine Health
2021-2024

Center for Molecular Dynamics - Nepal
2015-2023

University of California Davis Medical Center
2020-2022

Proteasomes and SUMO wrestle chromosomes Meiosis is the double cell division that generates haploid gametes from diploid parental cells. Pairing of homologous during first meiotic ensures each gamete receives a complete set chromosomes. The proteasome, on other hand, molecular machine degrades proteins tagged for destruction within (see Perspective by Zetka). Ahuja et al. show proteasome also involved in ensuring pair with meiosis. Rao (small ubiquitin-like modifier) protein, ubiquitin,...

10.1126/science.aaf6407 article EN Science 2017-01-06

Hypertrophic scars and keloids represent abnormal wound healing, manifesting as raised confined to or extending beyond the margin, respectively. Understanding risk factors associated with these scarring types is crucial for prevention management. Utilizing TriNetX global health research network database, we analyzed data of 6,249 patients hypertrophic keloids. We employed ICD-10 code L91.0 identification, generating a control cohort matched by age, sex, race. Associations between race,...

10.36849/jdd.8401 article EN Journal of Drugs in Dermatology 2025-01-01

Clinical evidence highlights the central nervous system as a key target in type-2 diabetes-related complications, yet mechanisms underlying increased prevalence of mood disorder issues, mainly depression, patients with diabetes remain poorly understood. Leptin, an adiposity hormone known for its role energy homeostasis, has been shown to improve insulin sensitivity and regulate blood glucose levels diabetic populations. Beyond metabolic effects, leptin also potential mitigate psychiatric...

10.1097/fbp.0000000000000820 article EN Behavioural Pharmacology 2025-03-10

Infliximab pharmacokinetics in steroid-refractory [SR] ulcerative colitis [UC] suggest a need for higher dosing, but data concerning efficacy of intensification this setting are lacking children and inconsistent overall.Paediatric patients [N = 125] treated with infliximab SR or steroid-dependent UC were retrospectively reviewed. Outcomes [clinical response remission, colectomy, mucosal healing, safety] standard vs intensified induction [mean dose ≥7 mg/kg interval ≤5 weeks between doses 1...

10.1093/ecco-jcc/jjz019 article EN Journal of Crohn s and Colitis 2019-01-23

Abstract Efforts to mitigate the increasing emergence of antimicrobial resistance (AMR) will benefit from a One Health perspective, as over half animal antimicrobials are also considered medically important in humans, and AMR can be maintained environment. This is especially pertinent low- middle-income countries community settings, where an estimated 80% all antibiotics used. study features genes found among animals, water at urban informal settlement Nepal with intensifying livestock...

10.1038/s41598-022-14781-y article EN cc-by Scientific Reports 2022-08-15

Minoxidil is an anti-hypertensive vasodilator increasingly used off-label for the treatment of alopecia. It associated with increased risk pericardial effusions, recent reports even in patients on low-dose oral minoxidil (LDOM) therapy.

10.36849/jdd.8029 article EN Journal of Drugs in Dermatology 2024-08-01

Tiger (Panthera tigris) populations are in danger across their entire range due to habitat loss, poaching and the demand for tiger parts. The Bengal tigris is an endangered apex predator with a population size estimated be less than 200 Nepal. In spite of strict wildlife protection laws, illegal trade parts increasing; Nepal has become one major sources transit routes poached Identification often challenging law enforcement officials inadequate training lack available tools. Here, we...

10.1371/journal.pone.0201639 article EN public-domain PLoS ONE 2018-08-23

Nepal boarders India and China all three countries lie within the Central Asian Flyway for migratory birds. Novel influenza A H7N9 caused human fatalities in 2013. Subclinical infections of birds potential virus dispersal by prompted this study to assess avian viral intrusion into Nepal. Surveillance was implemented early 2014 with assistance from Food Agricultural Organization (FAO). Of 1811 environmental fecal samples collected seven wetland bird roosting areas, H9N2 found one sample a...

10.1371/journal.pone.0133035 article EN cc-by PLoS ONE 2015-07-15
Coming Soon ...