A5079889407- Genomics and Phylogenetic Studies
- Chromosomal and Genetic Variations
- Cancer-related molecular mechanisms research
- RNA Research and Splicing
- Light effects on plants
- Molecular Biology Techniques and Applications
- Plant Pathogens and Resistance
- Silicon Effects in Agriculture
- Plant Disease Resistance and Genetics
- Plant Molecular Biology Research
- Plant Pathogenic Bacteria Studies
- Plant Virus Research Studies
- Greenhouse Technology and Climate Control
- Wheat and Barley Genetics and Pathology
- RNA modifications and cancer
Center for Life Sciences
2025
Peking University
2018-2025
State Key Laboratory of Protein and Plant Gene Research
2018
State Key Laboratory of Plant Genomics
2018
Chinese Academy of Sciences
2015-2016
Beijing Institute of Genomics
2015-2016
University of Chinese Academy of Sciences
2015
Watermelon, Citrullus lanatus, is the world's third largest fruit crop. Reference genomes with gaps and a narrow genetic base hinder functional genomics improvement of watermelon. Here, we report assembly telomere-to-telomere gap-free genome elite watermelon inbred line G42 by incorporating high-coverage accurate long-read sequencing data multiple strategies. All 11 chromosomes have been assembled into single-contig pseudomolecules without gaps, representing highest completeness quality to...
Three families of transcription factors have been reported to play key roles in light control Arabidopsis seedling morphogenesis. Among them, bHLH protein PIFs and plant-specific EIN3/EIN3-LIKE 1 (EIN3/EIL1) accumulate the dark maintain skotomorphogenesis. On other hand, HY5 HOMOLOG (HYH), two related bZIP proteins, are stabilized promote photomorphogenic development. To systemically investigate transcriptional regulation light-controlled morphogenesis, we generated HY5ox/pifQein3eil1, which...
The complete assembly of vast and complex plant genomes, like the hexaploid wheat genome, remains challenging. Here we present CS-IAAS, a comprehensive telomere-to-telomere (T2T) gap-free Triticum aestivum L. encompassing 14.51 billion base pairs featuring all 21 centromeres 42 telomeres. Annotation revealed 90.8 Mb additional centromeric satellite arrays 5,611 rDNA units. Genome-wide rearrangements, elements, transposable element expansion segmental duplications were deciphered during...
Two telomere-to-telomere, gap-free genome for Rubus species were sequenced and assembled by using an integrative approach that combined ultra-long reads from Oxford Nanopore Technology (ONT), PacBio high-fidelity (HiFi) long reads, Illumina paired-end short High-throughput Chromosome Conformation Capture (Hi-C) data, resulted in the first reference genomes of genus. By comparative genomics transcriptomics, we revealed conserved key genes associated with sugar accumulation genus, providing...
Transcripts are expressed spatially and temporally they very complicated, precise specific; however, most studies focused on protein-coding related genes. Recently, massively parallel cDNA sequencing (RNA-seq) has emerged to be a new promising tool for transcriptome research, numbers of non-coding RNAs, especially lincRNAs, have been widely identified well characterized as important regulators diverse biological processes. In this study, we used ultra-deep RNA-seq data from 15 mouse tissues...