A5074188050- Cellular Mechanics and Interactions
- Microtubule and mitosis dynamics
- Telomeres, Telomerase, and Senescence
- Adrenal Hormones and Disorders
- Glycosylation and Glycoproteins Research
- Endoplasmic Reticulum Stress and Disease
- Advanced Chemical Sensor Technologies
- 14-3-3 protein interactions
- Thyroid Disorders and Treatments
- Oral microbiology and periodontitis research
- Developmental Biology and Gene Regulation
- Retinal Development and Disorders
- Viral Infectious Diseases and Gene Expression in Insects
- Chronic Lymphocytic Leukemia Research
- Cancer Research and Treatments
- Nerve injury and regeneration
- Birth, Development, and Health
- Galectins and Cancer Biology
- Virus-based gene therapy research
- Autoimmune Neurological Disorders and Treatments
- Essential Oils and Antimicrobial Activity
- Cardiomyopathy and Myosin Studies
University of Pecs
2023-2024
HUN-REN Szegedi Biológiai Kutatóközpont
2021-2023
Institute of Genetics
2021-2023
Hungarian Research Network
2021
University of Liverpool
2017
Directed axonal growth depends on correct coordination of the actin and microtubule cytoskeleton in cone. However, despite relatively large number proteins implicated actin-microtubule crosstalk, mechanisms whereby polymerization is coupled to stabilization advancement peripheral cone remained largely unclear. Here, we identified formin Dishevelled-associated activator morphogenesis (DAAM) as a novel factor playing role concerted regulation remodeling Drosophilamelanogaster primary neurons....
Abstract Background Parallel to the growth of oral healthcare market, there is a constantly increasing demand for natural products as well. Many customers prefer that contain fewer toxic agents, therefore providing an environmentally friendly solution with benefit smaller risk user. Medieval and early modern medicinal knowledge might be useful when looking natural, herbal-based components develop products. Along these considerations we created, tested, compared entirely mouthwash, named...
This study aimed to evaluate the interrelationship between telomere length, telomerase activity and oxidative DNA damage in patients undergoing vitro fertilization (IVF). single-center, observational clinical comprised 102 unselected, consecutive with various infertility diagnoses. Granulosa cells (GCs) follicular fluid (FF) were analyzed simultaneously for functions marker of damage, 8-hydroxy-2-deoxyguanosine (8-OHdG). An Absolute Human Telomere Lengths Quantification qPCR Assay kit...
Abstract Background The purpose of our work was to provide a data-driven perspective autoimmune polyglandular syndrome (APS), complex disorder, supplementing traditional clinical observations. Methods Medical records 7559 patients were analyzed, and origin proved in 3180 cases which 380 (12%) had APS. Associations component disorders investigated by computational methods reveal typical patterns disease development. Results Twenty-eight distinct diagnosed forming 113 combinations. 10 most...
Instead of Western blot being considered as a gold standard for intracellular protein expression assays, we developed novel multiplexed high throughput (180 tests/day) in situ manual method directly 96-well plates using 25,000-100,000 cells/well after formaldehyde fixation and Triton X 100 permeabilization. HepG2 cells were treated with ochratoxin A (OTA) staurosporine (STP) to induce apoptosis. Antioxidant apoptotic cell signaling studied by various rabbit primary antibodies HRP labeled...
Directed axonal growth depends on correct coordination of the actin and microtubule cytoskeleton in cone.However, despite relatively large number proteins implicated actin-microtubule crosstalk, mechanisms whereby polymerization is coupled to stabilization advancement peripheral cone remained largely unclear.Here, we identified formin Dishevelled-associated activator morphogenesis (DAAM) as a novel factor playing role concerted regulation remodeling Drosophila melanogaster primary neurons.In...
Optical insulation of the unit eyes (ommatidia) is an important prerequisite precise sight with compound eyes. Separation ommatidia ensured by pigment cells that organize into a hexagonal lattice in Drosophila eye, forming thin walls between facets. Cell adhesion, mediated apically and latero-basally located junctional complexes, crucial for stable attachment these to each other basal lamina. Whereas former studies have focused on formation remodelling cellular connections at apical region,...
Recent studies proved that metabolic changes in malignant disorders have an impact on protein glycosylation, however, only a few attempts been made so far to use O-GlcNAc analysis as prognostic tool. Glucose metabolism is reported be altered hematological malignancies thus, we hypothesized monitoring intracellular levels Rai stage 0-I (Binet A) CLL patients could give deeper insights regarding subtle of progression which are not completely detected by the routine follow-up procedures.In this...