A5100406595- Thyroid Cancer Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- CO2 Sequestration and Geologic Interactions
- Pharmacological Effects of Natural Compounds
- Pancreatitis Pathology and Treatment
- Carbon Dioxide Capture Technologies
- Genetic factors in colorectal cancer
- Fluid Dynamics and Mixing
- Cancer-related Molecular Pathways
- Quantum Dots Synthesis And Properties
- Cancer, Stress, Anesthesia, and Immune Response
- Vagus Nerve Stimulation Research
- Carbon and Quantum Dots Applications
- Gout, Hyperuricemia, Uric Acid
- Estrogen and related hormone effects
- Ginseng Biological Effects and Applications
- Granular flow and fluidized beds
- Therapeutic Uses of Natural Elements
- Phonocardiography and Auscultation Techniques
- Artificial Intelligence in Healthcare and Education
- Neuropeptides and Animal Physiology
- Long-Term Effects of COVID-19
- Cyclone Separators and Fluid Dynamics
- Pharmacological Effects of Medicinal Plants
- Inflammatory Bowel Disease
Seoul National University
2017-2024
Gyeongsang National University Hospital
2024
University of California, San Diego
2023
Children's Hospital of Los Angeles
2023
McGill University
2023
Samsung Medical Center
2021
National Cancer Institute
2020
National Institutes of Health
2020
Center for Cancer Research
2020
Kyungpook National University
2016
Abstract Purpose To examine the ability of generative artificial intelligence (GAI) to answer patients’ questions regarding colorectal cancer (CRC). Methods Ten clinically relevant about CRC were selected from top-rated hospitals’ websites and patient surveys presented three GAI tools (Chatbot Generative Pre-Trained Transformer [GPT-4], Google Bard, CLOVA X). Their responses compared with answers information book. Response evaluation was performed by two groups, each consisting five...
Colloidal nanocrystal quantum-dot (QD)-based light-emitting diodes (QLEDs) represent a highly promising technology for next-generation displays, utilizing the distinctive optical characteristics of QDs to generate vivid and precise colors. For decades, extensive research efforts have been dedicated synthesis engineering QLEDs, with ultimate goal making them practically applicable. Notably, majority has concentrated on performance enhancements that are predominantly attributed intrinsic...
Lupeol is a triterpenoid commonly found in fruits and vegetables known to exhibit wide range of biological activities, including antiinflammatory anti-cancer effects. However, the effects lupeol on acute pancreatitis specifically have not been well characterized. Here, we investigated cerulein-induced mice. Acute was induced via an intraperitoneal injection cerulein (50 µg/kg). In treatment group, administered intraperitoneally (10, 25, or 50 mg/kg) 1 h before first injection. Blood samples...
Cross-talk between mitogen-activated protein kinase and estrogen has been reported; however, the role of BRAFV600E in responsiveness thyroid cancer is unknown. We elucidated effect on estrogen-induced increase metastatic potential cancer. Using a pair cell lines, human lines which harbor wild type BRAF gene (Nthy/WT) Nthy/BRAFV600E (Nthy/V600E), expression receptors (ERs) phenotypes were evaluated. Susceptibility to ERα- ERβ-selective agents was evaluated confirm differential ER expression....
We develop a rigorous mathematical model of aqueous mineral carbonation kinetics for carbon capture and utilization (CCU) estimate the parameter posterior distribution using Bayesian estimation framework lab-scale experiments. conduct 16 experiments according to orthogonal array design an additional one experiment test. The considers gas–liquid mass transfer, solid dissolution, ionic reactions, precipitations, discrete events in form differential algebraic equations (DAEs). framework, which...
Background: Mutations of the thyroid hormone receptor α (THRA) gene cause resistance to (RTHα). RTHα patients exhibit very mild abnormal function test results (serum triiodothyronine can be high-normal high; thyroxine normal low; thyrotropin is or mildly raised) but manifest hypothyroid symptoms with growth retardation, delayed bone development, and anemia. Much has been learned about in vivo molecular actions TRα1 mutants affecting growth, anemia by using a mouse model (Thra1PV/+ mice)....
Preoperative diagnosis of thyroid nodules reduces unnecessary surgery. Circulating tumor cells (CTCs) may contain information primary tumor(s). We asked whether the peripheral blood expression genes specific for circulating differentiates benign from malignant nodules. Peripheral mononuclear nodule patients (n = 20) were isolated preoperatively and seven CTC-associated was measured in with nodule(s) 20). Among tested genes, SLC5A5 LGALS3 validated a larger number 64) our results show that...
Background: Despite active studies of the clinical importance BRAFV600E, suitable research models to investigate role this mutation in etiopathogenesis human thyroid cancers are limited. Thus, we generated cell lines by transducing simian virus (SV)-40 immortalized line Nthy-ori 3-1 (Nthy) with lentiviral vectors expressing either BRAFWT (Nthy/WT) or BRAFV600E. Nthy/WT and Nthy/V600E cells were then xenografted into mice evaluate carcinogenic Methods: Each was subcutaneously injected...
Super refractory status epilepticus (SRSE) is a condition in which persists despite 48 hours of anesthetic treatment. Nonconvulsive (NCSE) characterized by seizures lasting more than 30 min on an electroencephalogram, with accompanying changes behavior or consciousness without convulsions. Prompt treatment NCSE crucial, as delayed may lead to additional brain damage and progression convulsive epilepticus. Although vagus nerve stimulation (VNS) has been approved adjunct for drug-resistant...
Deep neural network trained with massive labeled dataset has shown impressive performance in multiple disease classification tasks for chest X-ray radiograph (CXR). However, different imaging protocols even the same such as posteroanterior (PA) and anteroposterior (AP) CXR often lead to domain gap, causing significant degradation requiring more images painstaking labeling. We propose a novel adaptation scheme via deep converter (DNC) scenario of having PA unlabeled AP; converting into AP...
Abstract Background: Tumor-associated macrophages (TAMs) exert a range of immunomodulatory functions in the tumor microenvironment (TME) and have been considered key regulators development. The interactions TAMs with cancer stromal cells TME shown to promote sustain progression; however, are largely phenotypically functionally heterogeneous. Studies at single-cell level therefore necessary understand biological clinical relevance heterogeneity TAMs. Objective: To investigate TAM populations...