- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Cardiac Imaging and Diagnostics
- Obstructive Sleep Apnea Research
- Coronary Interventions and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Kawasaki Disease and Coronary Complications
- Blood Pressure and Hypertension Studies
- Cerebrovascular and Carotid Artery Diseases
- Acute Myocardial Infarction Research
- Organ Transplantation Techniques and Outcomes
- Cardiovascular Function and Risk Factors
- Alzheimer's disease research and treatments
- Cardiac Arrest and Resuscitation
- Coronary Artery Anomalies
- Cardiovascular Health and Disease Prevention
- Chronic Kidney Disease and Diabetes
- Hate Speech and Cyberbullying Detection
- Cardiac and Coronary Surgery Techniques
- Electronic Health Records Systems
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Hydrogels: synthesis, properties, applications
Stanford University
2025
Ho Chi Minh City University of Technology and Education
2024
Rowan University
2024
University of Colorado Denver
2021-2023
Children's Hospital Colorado
2021-2023
University of Colorado Anschutz Medical Campus
2021-2022
Can Tho University
2022
The University of Melbourne
2005-2021
Centre for Eye Research Australia
2007-2021
Monroe Carell Jr. Children's Hospital
2016-2017
OBJECTIVE—To examine the relationship of retinal vascular caliber with diabetes, glycemia, and diabetic retinopathy. RESEARCH DESIGN AND METHODS—Population-based study using data from Multi-Ethnic Study Atherosclerosis (MESA), comprising 5,976 individuals (whites, blacks, Hispanics, Chinese) residing in six U.S. communities who were free clinical cardiovascular disease at baseline. Retinal was measured digital photographs. RESULTS—There 4,585 normal fasting glucose (NFG), 499 impaired (IFG),...
OBJECTIVE Flicker light–induced retinal vasodilation may reflect endothelial function in the circulation. We investigated flicker individuals with diabetes and diabetic retinopathy. RESEARCH DESIGN AND METHODS Participants consisted of 224 103 nondiabetic control subjects. (percentage increase over baseline diameter) was measured using Dynamic Vessel Analyzer. Diabetic retinopathy graded from photographs. RESULTS Mean ± SD age 56.5 11.8 years for those 48.0 16.3 arteriolar venular dilation...
To describe and compare the associations of serum lipoproteins apolipoproteins with diabetic retinopathy.This was a cross-sectional study 224 patients (85 type 1 139 2) from diabetes clinic. Diabetic retinopathy graded fundus photographs according to Airlie House Classification system categorized into mild, moderate, vision-threatening (VTDR). Serum traditional lipids (total, LDL, non-HDL, HDL cholesterol triglycerides) apolipoprotein AI (apoAI), B (apoB), apoB-to-apoAI ratio were...
OBJECTIVE—To examine the relationship of retinal vascular caliber to incident diabetes in a population-based cohort. RESEARCH DESIGN AND METHODS—The Australian Diabetes, Obesity and Lifestyle (AusDiab) Study recruited adults aged 25+ years across Australia 1999–2000, with follow-up 5 later 2004–2005. Participants' glycemic status was classified using fasting plasma glucose (FPG) 2-h oral tolerance (2-h [2hPG]) tests. Diabetes diagnosed if FPG ≥7.0 mmol/l or 2hPG ≥11.1 mmol/l. Retinal...
OBJECTIVE There are conflicting data regarding relationships of systemic biomarkers inflammation, hemostasis, and homocysteine with diabetic retinopathy. We examined these in the Multi-Ethnic Study Atherosclerosis. RESEARCH DESIGN AND METHODS A total 921 participants diabetes were included. Diabetic retinopathy was graded from retinal photographs. defined two outcomes: any vision-threatening (severe nonproliferative or worse). Systemic markers analyzed C-reactive protein, homocysteine,...
Fabry disease is a rare X-linked inborn error of glycosphingolipid metabolism. The aim this study was to document the ophthalmological manifestations patients attending Royal Melbourne Hospital treatment centre.Patients at centre had full examination performed. This included best corrected visual acuity, ocular motility and adnexae. Patients also underwent slit-lamp looking for presence features disease, particularly examining bulbar conjunctiva, cornea, lens fundus.Thirty-four hemizygous...
Subtle changes in retinal vascular caliber have been shown to predict diabetic retinopathy and other complications. This study was undertaken investigate whether correlates with light-flicker-induced vasodilation, a measure of endothelial function.The participants were 224 persons diabetes (85 type 1 139 2) 103 without (controls). Flicker-induced vasodilation (percentage increase over baseline diameter) measured vessel analyzer. Retinal from digital photographs according standardized,...
Retinal vascular caliber changes have been shown to predict stroke, but the underlying mechanism of this association is unknown. We examined relationship between retinal with brachial flow-mediated dilation (FMD), a measure systemic endothelial function.The Multi-Ethnic Study Atherosclerosis (MESA) population-based study persons 45 84 years age residing in 6 US communities free clinical cardiovascular disease at baseline. Brachial FMD data were collected baseline (July 2000 June 2002), and...
Objective: To examine retinal vascular caliber, an indicator of early microvascular disease and depression in patients with Type 2 diabetes. Methods: We conducted a clinic-based study, comparing participants diabetes major (n = 43), without 49), healthy controls or 54). Retinal caliber was measured from digital photographs. Depression status determined, using standardized clinical assessment. Results: After adjusting for age gender, had larger arteriolar venular calibers (147.7 μm 215.7...
To investigate the impact of retesting frequency over a short period on flicker light-induced retinal vasodilation.Twenty healthy participants were included. The vascular response to light stimulation was assessed three times (at baseline and after 5 30 minutes rest [tests 1, 2, 3, respectively]) in each participant using Dynamic Vessel Analyzer. Relative dilations selected arteriole venule segments during resting diameters measured automatically. mean vessel compared repeated-measures...
We hypothesize that late-life depression is a manifestation of microvascular disease in patients with type 2 diabetes. conducted clinic-based cross-sectional study, comparing retinal vascular caliber, marker disease, participants diabetes major (n=34), without (n=27) and healthy non-diabetic controls (n=38). Retinal caliber was measured from digital photographs using validated computer-assisted method. After adjusting for age gender, there trend increasing arteriolar (132.6 microm), to...
Neurogenic pulmonary edema is a clinical syndrome that manifests as an acute onset of in the setting central nervous system injury, without cardiac dysfunction. rare children, and mechanism still not completely understood. The pathology overlaps with lung injury respiratory distress syndrome. authors report case 14-month-old previously healthy child who presented febrile status epilepticus, fulminant neurogenic edema, should be considered differential diagnosis for rapid progression failure...