A5018839865- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Ophthalmology and Visual Impairment Studies
- Enhanced Recovery After Surgery
- Spectroscopy Techniques in Biomedical and Chemical Research
- Retinal and Optic Conditions
- Colorectal Cancer Surgical Treatments
- Renal and Vascular Pathologies
- Industrial Vision Systems and Defect Detection
- Optical measurement and interference techniques
- Racial and Ethnic Identity Research
- Antioxidant Activity and Oxidative Stress
- Advanced Measurement and Metrology Techniques
- Neurological Disease Mechanisms and Treatments
- Visual perception and processing mechanisms
- Appendicitis Diagnosis and Management
- Otolaryngology and Infectious Diseases
- Hip and Femur Fractures
- Inflammatory mediators and NSAID effects
- Heme Oxygenase-1 and Carbon Monoxide
- Streptococcal Infections and Treatments
- Manufacturing Process and Optimization
Monash Health
2025
Singapore Eye Research Institute
2022-2024
Singapore National Eye Center
2021-2023
Chinese Community Health Resource Center
2022
University of California, San Francisco
2022
Centre for Eye Research Australia
2016-2021
The University of Melbourne
2016-2021
Universitas Trisakti
2018-2019
Belfast City Hospital
2016-2018
University of Ulster
2016-2018
Introduction Diabetic retinopathy (DR) is a leading cause of preventable blindness among working-age adults, primarily driven by ocular microvascular complications from chronic hyperglycemia. Comprehending the complex relationship between changes in eye and disease progression poses challenges, traditional methods assuming linear or logistical relationships may not adequately capture intricate interactions these advances. Hence, aim this study was to evaluate involvement diabetes mellitus...
Purpose: We determine the feasibility of using a dark-adapted chromatic (DAC) perimeter to obtain static and dynamic rod function at multiple retinal locations, compare these functional parameters between subjects with intermediate age-related macular degeneration (AMD) normal controls. Methods: Perimetric sensitivities for 505 620 nm stimuli across 7 locations within central 12° were repeatedly measured after exposing single photobleach in 22 AMD 8 The each stimulus 20 minutes bleach...
To use optical coherence tomography angiography (OCTA) parameters from both the retinal and choroidal microvasculature to detect presence severity of diabetic retinopathy (DR).This is a cross-sectional case-control study. OCTA vasculature, fovea avascular zone (FAZ) choriocapillaris were evaluated 3×3 mm2 fovea-centred scans. Areas under receiver operating characteristic (ROC) curve used compare discriminative power on diabetes mellitus (DM), DR need for referral: group 1 (no DM vs no DR), 2...
Abstract Background Superficial abscess of the skin is a common emergency presentation often requiring surgical management. Ambulatory Care Pathways (ACPs) are method that can reduce burden this disease on hospital bed pressure by treating patients with superficial abscesses as day cases. We conducted prospective cohort study to assess safety and effectiveness an ACP for meeting strict criteria abscess. Methods Data new management was collected 12 months from June 20th, 2021 compared...
Purpose: To evaluate rod function longitudinally in intermediate age-related macular degeneration subjects with reticular pseudodrusen (RPD) and without RPD (AMD). Methods: Retinal sensitivities (505 625 nm) during dark adaptation, at 14 locations within the central 12° macula were obtained after photobleaching baseline 12-month visits. Pointwise sensitivity differences between both stimuli used to assess static function, while intercept time (RIT) recovery rate (RRR) dynamic function....
To compare static rod function obtained with and without photobleach in control intermediate age-related macular degeneration (iAMD) participants subretinal drusenoid deposits (SDD).In this cross-sectional study, retinal sensitivities within the central 24° retina were twice using a dark-adapted chromatic perimeter, both 505- 625-nm stimuli. Tests performed after 30 minutes of dark-adaptation either or preceding photobleach. Multimodal imaging was to grade AMD SDD status, other changes...
Purpose: Although impairment of rod function in the early stages age-related macular degeneration (AMD) has been well recognized, data on longitudinal changes at multiple retinal locations remain limited. This study investigated retinotopic eyes with intermediate AMD (iAMD). Methods: Complete ophthalmic examination, multimodal imaging, and scotopic perimetry were performed baseline 12-month follow-up. Perimetric sensitivities for 505-nm stimulus repeatedly measured 20 minutes after exposing...
Purpose: To evaluate whether a practical method of imaging lenticular autofluorescence (AF) can provide an individualized measure correlated with age-related lens yellowing in older subjects undergoing tests involving shorter wavelength lights. Methods: Lenticular AF was imaged 488-nm excitation using confocal scanning laser ophthalmoscope (cSLO) routinely used for retinal imaging. There were 75 (ages 47–87) at two sites; small cohort younger served as controls. At one site, the cSLO...
Purpose: To determine the intrasession and intersession test–retest repeatability of retinal sensitivity measurements using a dark-adapted chromatic perimeter (DACP). Methods: For testing, within central 24° for 505-nm stimulus was measured after 20, 30, 40 minutes dark adaptation (DA) 625-nm first second tests. both stimuli 30 DA at baseline 1 month. The point-wise (PWS) difference coefficient (CoR) each group were determined. Results: 10 age-related macular degeneration (AMD) eight control...
Purpose: Identifying the most sensitive functional measure in intermediate age-related macular degeneration (iAMD) could help select an appropriate test for monitoring disease progression and evaluating efficacy of novel interventions early stages AMD. The purpose study was to determine which commonly used visual function is discriminatory when comparing individuals with iAMD normal participants. Methods: In this prospective observational study, cases healthy controls underwent testing (best...
Aims To evaluate the effectiveness of glaucoma screening using suspect (GS) referral criteria assessed on colour fundus photographs in Singapore’s Integrated Diabetic Retinopathy Programme (SiDRP). Methods A case–control study. This study included diabetic subjects who were referred from SiDRP with and without GS between January 2017 December 2018 reviewed at Singapore National Eye Centre. The based presence a vertical cup-to-disc ratio (VCDR) ≥0.65 other features. final diagnosis confirmed...
To quantify the association between dark adaptation parameters and other clinical measures of visual function among people with without early intermediate age-related macular degeneration (AMD).In this cross-sectional study, participants underwent multimodal imaging testing, including best-corrected acuity (BCVA), low-luminance (LLVA), deficit (LLD = BCVA - LLVA) 10-item Night Vision Questionnaire (NVQ-10). Dynamic static dark-adapted chromatic perimetry (DACP) was performed. Sensitivity...