A5026453780- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Research Studies
- Neuroendocrine Tumor Research Advances
- Colorectal and Anal Carcinomas
- Inflammatory Biomarkers in Disease Prognosis
- Lymphoma Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Metastasis and carcinoma case studies
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Ovarian cancer diagnosis and treatment
- Cancer Diagnosis and Treatment
- Advanced Breast Cancer Therapies
- Venous Thromboembolism Diagnosis and Management
- Head and Neck Cancer Studies
- Cancer, Lipids, and Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal cell carcinoma treatment
- Radiomics and Machine Learning in Medical Imaging
- Salivary Gland Tumors Diagnosis and Treatment
- Cardiac tumors and thrombi
- Intraperitoneal and Appendiceal Malignancies
Istanbul Yeni Yüzyıl University
2023-2024
Aesthetic Surgery Center
2023
Cyprus International University
2023
Trakya University
2018-2019
Ankara Numune Eğitim ve Araştırma Hastanesi
2015-2019
Sağlık Bilimleri Üniversitesi
2018
Ankara Yıldırım Beyazıt University
2018
Bahçeşehir University
2017
Gazi University
2017
Bülent Ecevit University
2017
The aim of this study was to evaluate the prognostic importance albumin globulin ratio (AGR) in terms overall survival (OS) and progression free (PFS) metastatic gastric cancer patients.The patients diagnosed with between 2009 April 2016 at hospital have been studied retrospectively. clinicopathological characteristics, laboratory, treatment parameters assessed. AGR value has calculated using following formula (AGR = serum albumin/total protein - albumin).In total, 251 were included...
The prognostic significance of serum gamma-glutamyl transferase (GGT) level at diagnosis in patients with metastatic non-small lung cancer (NSCLC) is not clear. We aimed to assess the relationship between GGT and overall survival (OS) progression-free (PFS) this patient population.Data NSCLC who were admitted medical oncology clinic our hospital during April 2013-December 2017 retrospectively analyzed. Patients divided into two groups based on levels, normal high (as defined by reference...
The aim of this study was to evaluate the efficacy and toxicity profile oral etoposide (50 mg/day, days 1-14, every 3 weeks) in recurrent platinum-resistant epithelial ovarian cancer (EOC). 52 EOC patients followed up four centres between April 2000 December 2013 were analysed retrospectively. There response a total 21 [partial (PR) stable disease (SD)], 12 them used second third, 9 it fourth- fifth-lines treatment. overall rate 19.2% clinical benefit 40.4% [PR (19.2%), SD (21.2%)]. Median...
Aim: To determine whether there are any clinicopathological or prognostic differences between mucinous gastric carcinoma (MGC) and signet ring cell (SRCC).Methods: Pathological parameters, clinical treatment efficacy were compared in patients with MGC SRCC.Results: In total, 193 (51 142 SRCC) included this study. Patients SRCC particular had notably higher lymphovascular invasion, perineural rate of Borrmann types III IV, stage III–IV cancer (according to its TNM stage) MGC. However, tumor...
Introduction: This study aims to investigate the prognostic significance of pre-treatment hemoglobin-red blood cell distribution width (RDW) ratio (HRR) in terms overall survival (OS) and disease-free (DFS) patients with locally advanced nasopharyngeal cancer (LANC) treated chemoradiotherapy. Methods: Patients LANC who attended oncology clinic between October 2010 June 2020 were retrospectively screened. HRR was calculated as hemoglobin (g/dL) divided by RDW (%). assigned either low group or...
The aim of the present study was to determine whether there are any clinicopathological or prognostic differences between patients with α-fetoprotein-secreting gastric carcinoma (AFP-SGC) and non-AFP-SGC. Pathological parameters, clinical treatment efficacy were compared in AFP-SGC In total, 362 (53 309 non-AFP-SGC) included study. Patients had significantly higher levels lymphovascular invasion, perineural invasion (PNI), rate liver metastasis, stage IV cancer non-AFP-SGC (P<0.05). median...
Studies on the effects of third-line chemotherapy (CT) in advanced gastric cancer (GC) patients are still scarce. The aim this study was to evaluate efficacy and safety modified 5-fluorouracil, leucovorin, irinotecan (mFOLFIRI) regimen as a CT metastatic GC patients, after failure fluoropyrimidine, platinum, anthracycline, taxane. After first- second-line therapies, 42 received FOLFIRI (180 mg/m² 400 leucovorin administered concomitantly 90-minute intravenous (IV) infusion day 1, followed by...
Modified docetaxel, cisplatin, and 5-fluorouracil (mDCF) therapy has been shown to be a well tolerated highly effective regimen for metastatic gastric carcinoma. Herein we investigated the effectiveness of mDCF combination as first-line treatment in patients with recurrent/metastatic squamous cell carcinoma head neck (HNSCC).A total 80 HNSCC who were treated between 2009 2015 enrolled into this study. All 2-6 cycles chemotherapy which consisted docetaxel 60 mg/m2 intravenously (IV) on day 1,...
To analyze the relationship between clinical features, hormonal receptor status, and survival in patients who were diagnosed with medullary breast cancer (MBC). Methods: Demographic characteristics, histopathological statuses of 201 MBC 1995 2015 retrospectively recorded. Survival analyses conducted uni- multivariate cox regression analysis.Median follow-up time was 54 (4-272) months. Median patient age at diagnosis 47 years old (26-90). Of patients, 91.5% triple negative. Five-year...
In this study, our aim was to identify the main predictive factors associated with pathologic complete response (pCR) neoadjuvantchemoradiotherapy (nCRT) in patients locally advanced rectal cancer. The who had cancer and underwent a long-course nCRT, followed by curative surgery between January 2009 December 2015 at two-center were included. clinical pCR or non-pCR analyzed Logistic regression. Two hundred three included study. Forty-six (22.7%) 157 (77.3%) non-pCR. univariate analysis, no...
To evaluate the prognostic significance of plasma caveolin (CAV)-1 and its association with survival treatment response rates in metastatic pancreatic cancer (MPC).Plasma samples were prospectively collected from 41 patients newly diagnosed MPC. Moreover, 48 chronic pancreatitis healthy individuals (control groups) for assessing Cav-1 levels. Plasma levels evaluated at baseline after three cycles chemotherapy MPC.The median level was 13.8 ng/mL MPC 12.2 (P = 0.009). The cut-off calculated as...
The current study aimed to compare the clinicopathological characteristics and survival data of patients with metastatic colorectal cancer who had symptomatic or asymptomatic venous thromboembolism (VTE) non-VTE.The files diagnosed 521 in our hospital between April 2001 January 2015 were analyzed retrospectively. VTE was divided into four groups relation their locations as extremity, port, visceral, nonvisceral VTE. also categorized presence thrombus-related symptoms. median overall...
BACKGROUND:The potential prognostic value of survivin is variably reported depending on the gastric cancer. OBJECTIVE: Evaluation and predictive significance serum its relation with survival treatment response rates in patients locally advanced can cer (LAGC). METHODS:Serum samples were prospectively collected from 50 newly diagnosed LAGC. Serum 32 healthy subjects also as control groups for levels. levels evaluated at baseline after three cycles neoadjuvant chemotherapy LAGC patients....
The aim of this retrospective study was to investigate the clinicopathological characteristics patients with signet-ring cell carcinoma (SRCC) stomach, and efficacy modified docetaxel, cisplatin, fluorouracil (mDCF) chemotherapy regimen.Sixty-five diagnosed metastatic or recurrent SRCC treated at least one course mDCF regimen as first-line treatment our hospital July 2007 January 2015, were included in study. protocol comprised docetaxel 60 mg/m2/day (day 1), cisplatin 5-fluorouracil 600...
AIM: To emphasize the signifi cance of platelet-to-lymphocyte ratio (PLR) in estimating postoperative prognosis or survival measures patients with carcinoma ampulla Vater.METHODS: We retrospectively reviewed 82 patients, who underwent pancreaticoduodenectomy for ampullary between July 2001 and April 2014.We investigated predictive preoperative PLR disease-free (DFS) overall (OS).The possible correlations clinical pathological features were also evaluated.RESULTS: The 5-year DFS OS rates...