Bert Heinrichs
A5004040001- Ethics in medical practice
- Medical and Health Sciences Research
- Ethics in Clinical Research
- Ethics and Legal Issues in Pediatric Healthcare
- Philosophical Ethics and Theory
- Political Philosophy and Ethics
- War, Ethics, and Justification
- Biomedical Ethics and Regulation
- Neuroethics, Human Enhancement, Biomedical Innovations
- Artificial Intelligence in Healthcare and Education
- Palliative Care and End-of-Life Issues
- Patient Dignity and Privacy
- Kantian Philosophy and Modern Interpretations
- Attention Deficit Hyperactivity Disorder
- Economic and Social Issues
- Psychology of Moral and Emotional Judgment
- Healthcare Decision-Making and Restraints
- Explainable Artificial Intelligence (XAI)
- German Social Sciences and History
- Religion, Theology, and Education
- Child and Adolescent Health
- German Literature and Culture Studies
- Ethics and Social Impacts of AI
- Neurotransmitter Receptor Influence on Behavior
- Law and Political Science
Forschungszentrum Jülich
2015-2024
Institute of Science and Ethics
2005-2024
University of Bonn
2015-2024
Deutsches Herzzentrum der Charité
2017-2020
King's College London
2019
Université de Rennes
2019
Trinity College Dublin
2019
Intuit (United States)
2014
Westfälische Hochschule
1987
During rest, brain activity is synchronized between different regions widely distributed throughout the brain, forming functional networks. However, molecular mechanisms supporting connectivity remain undefined. We show that networks defined with resting-state magnetic resonance imaging can be recapitulated by using measures of correlated gene expression in a post mortem tissue data set. The set 136 genes we identify significantly enriched for ion channels. Polymorphisms this affect large...
Novelty-seeking tendencies in adolescents may promote innovation as well problematic impulsive behaviour, including drug abuse. Previous research has not clarified whether neural hyper- or hypo-responsiveness to anticipated rewards promotes vulnerability these individuals. Here we use a longitudinal design track 144 novelty-seeking at age 14 and 16 determine activity response predicts use. We find that diminished BOLD mesolimbic (ventral striatal midbrain) prefrontal cortical (dorsolateral...
This document presents the Bonn PRINTEGER Consensus Statement: Working with Research Integrity—Guidance for research performing organisations. The aim of statement is to complement existing instruments by focusing specifically on institutional responsibilities strengthening integrity. It takes into account daily challenges and organisational contexts most researchers. intends make integrity recognisable from work-floor perspective, providing concrete advice measures strengthen statement,...
Abstract Computer systems for medical diagnosis based on machine learning are not mere science fiction. Despite undisputed potential benefits, such may also raise problems. Two (interconnected) issues particularly significant from an ethical point of view: The first issue is that epistemic opacity at odds with a common desire understanding and potentially undermines information rights. second (related) concerns the assignment responsibility in cases failure. core two seems to be concepts...
Abstract In this paper, I examine whether the use of artificial intelligence (AI) and automated decision-making (ADM) aggravates issues discrimination as has been argued by several authors. For purpose, first take up lively philosophical debate on present my own definition concept. Equipped with account, subsequently review some recent literature AI/ADM discrimination. explain how account helps to understand that general claim in view aggravation is unwarranted. Finally, argue can, fact,...
Significance We characterize in humans a coordinated network of brain activity describing neurobehavioral correlates reward anticipation. The involves nodes striatal and cortical regions, which are preferentially associated with distinct externalizing behaviors—hyperactivity alcohol consumption—suggesting that the heterogeneity reward-related behaviors might be accounted for by different association patterns their connecting links. In genome-wide study node subsequent functional validation...
Alcohol abuse is highly prevalent, but little understood about the molecular causes. Here, we report that Ras suppressor 1 (Rsu1) affects ethanol consumption in flies and humans. Drosophila lacking Rsu1 show reduced sensitivity to ethanol-induced sedation. We required adult nervous system for normal it acts downstream of integrin cell adhesion molecule upstream Ras-related C3 botulinum toxin substrate (Rac1) GTPase regulate actin cytoskeleton. In an preference assay, global loss causes high...
Abstract In this paper, we use some elements of the philosophical theories Wilfrid Sellars and Robert Brandom for examining interactions between humans machines. particular, adopt concept space reasons analyzing status artificial intelligent agents (AIAs). One could argue that AIAs, like widely used recommendation systems, have already entered reasons, since they seem to make knowledge claims as premises further claims. This, in turn, can lead a sense alienation because AIAs do not quite...
The debate regarding prediction and explainability in artificial intelligence (AI) centers around the trade-off between achieving high-performance accurate models ability to understand interpret decisionmaking process of those models. In recent years, this has gained significant attention due increasing adoption AI systems various domains, including healthcare, finance, criminal justice. While are desirable goals principle, spread high accuracy yet opaque machine learning (ML) algorithms...
Although the principle of informed consent is well established and its importance widely acknowledged, it has met with criticism for decades. Doubts have been raised a number different reasons. In particular, empirical data show that people regularly fail to reproduce information provided them. Many critics agree, therefore, received concept no more than myth. Strategies overcome this problem often rest on flawed consent. paper, suggested communicative act between two persons. The challenge...
Will brain imaging technology soon enable neuroscientists to read minds? We cannot answer this question without some understanding of the state art in neuroimaging. But neither can we concept invoked by term “mind reading.” This article is an attempt develop such understanding. Our analysis proceeds two stages. In first stage, provide a categorical explication mind reading. The articulates empirical conditions that must be satisfied if reading achieved. second metric for judging proficiency...