A5070178364- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
- Immunotherapy and Immune Responses
- Cancer Genomics and Diagnostics
- Caveolin-1 and cellular processes
- Organ Transplantation Techniques and Outcomes
- Cancer Immunotherapy and Biomarkers
- MicroRNA in disease regulation
- Cell Adhesion Molecules Research
- CAR-T cell therapy research
- Reproductive Biology and Fertility
- Extracellular vesicles in disease
- Liver physiology and pathology
- Sperm and Testicular Function
- Genetic Mapping and Diversity in Plants and Animals
- Inflammatory Myopathies and Dermatomyositis
- Cancer-related molecular mechanisms research
- Liver Disease Diagnosis and Treatment
Poznan University of Medical Sciences
2013-2024
Cancer metastatic spread to serous cavity causes malignant pleural effusions (MPEs), indicating dismal prognosis. Tumor microenvironment can implement suppressive activity on host immune responses. Thus, we investigated the prevalence of Tregs and relationship between them TGF- β IL-10 concentrations measured expression FOXP3 , CTLA-4 CD28 GITR genes, as well protein selected genes in benign MPEs. The percentage was determined by means multicolor flow cytometry system. were using human 1...
Mammalian cumulus–oocyte complexes (COCs) reach full developmental capability during folliculogenesis and oogenesis. It is well recognized that only gametes achieving MII stage after in vivo or vitro maturation (IVM) are successfully fertilized by a single spermatozoon. Although the process of oocyte nuclear and/or cytoplasmic pigs determined, there exist many differences promote these processes vitro. Therefore, this study aimed to investigate RNA expression profiles between porcine oocytes...
Background. Rheumatoid arthritis (RA) is a chronic autoimmune disease leading to destructive changes in peripheral joints and their irreversible deformity. The influx of chemoattractant-mediated inflammatory cells the one main features RA.Objectives. aim this study was investigate effect knockdown caveolin-1 (CAV1), known regulator multiple cell signaling pathways, on chemokine (C-C motif) ligand 2/monocyte chemoattractant protein-1 (CCL2/MCP-1) expression synovial fluid-derived...
Non-small cell lung cancer (NSCLC) leads as a primary cause of cancer-related premature mortality in Western populations. This study leverages cutting-edge gene-expression-profiling technologies to perform an in-depth molecular characterization NSCLC specimens, with the objective uncovering tumor-specific genomic alterations. By employing DNA microarray analysis, our research aims refine classification for early detection, guide molecular-targeted treatment approaches, enhance...
Regulatory T cells (Tregs) is heterogenic subpopulation of that able to suppress function effector during the immune response. Among them are natural (nTreg) and induced Treg (Tr1, Th3, CD4+CD25-). CD25, CD45Ro, CD152, GITR, LAG-3, several adhesion molecules, chemokine receptors as well Toll-like present on surface Treg. Mechanism suppression used by nTreg not completely understood.
AMA Mania A, Kaczmarek M, Mozer-Lisewska I, et al. Hepatic stellate cells (HSC) cell line (LX-2) and Toll-like receptors – phenotypic/mRNA expression in vitro functional studies. Central European Journal of Immunology. 2013;38(4):486-493. doi:10.5114/ceji.2013.39766. APA Mania, A., Kaczmarek, M., Mozer-Lisewska, I., Kowala-Piaskowska, Kolecka-Bednarczyk, & Frydrychowicz, M. (2013). Immunology, 38(4), 486-493. https://doi.org/10.5114/ceji.2013.39766 Chicago Anna, Mariusz Iwona Arleta Agata...
Regulatory T cells (Tregs) is heterogenic subpopulation of that able to suppress function effector during the immune response. Among them are natural (nTreg) and induced Treg (Tr1, Th3, CD4+CD25-). CD25, CD45Ro, CD152, GITR, LAG-3, several adhesion molecules, chemokine receptors as well Toll-like present on surface Treg. Mechanism suppression used by nTreg not completely understood.