A5079587825- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Insect Pest Control Strategies
- Insect and Pesticide Research
- Computational Drug Discovery Methods
- Insect Resistance and Genetics
- RNA modifications and cancer
- Mosquito-borne diseases and control
- Gut microbiota and health
- Cancer-related molecular mechanisms research
- Genetic factors in colorectal cancer
- Essential Oils and Antimicrobial Activity
- Malaria Research and Control
- Genetics, Bioinformatics, and Biomedical Research
- Phytochemicals and Antioxidant Activities
- Plant and animal studies
- Synthesis and biological activity
- Mitochondrial Function and Pathology
- Cancer Genomics and Diagnostics
- Antibiotic Resistance in Bacteria
- Autism Spectrum Disorder Research
- Glutathione Transferases and Polymorphisms
- Natural Antidiabetic Agents Studies
- COVID-19 Clinical Research Studies
- Insect-Plant Interactions and Control
Mizoram University
2016-2025
Aizawl Adventist Hospital
2018-2024
Universidad Autónoma de la Ciudad de México
2024
Creative Commons
2023
Avinashilingam University
2023
Institute for Health Metrics and Evaluation
2021-2022
University of Washington
2021-2022
National Health and Medical Research Council
2022
Guru Gobind Singh Indraprastha University
2021
Tamil Nadu Agricultural University
2020
Isolation of DNA from blood and buccal swabs in adequate quantities is an integral part forensic research analysis. The present study was performed to determine the quality quantity extracted four commonly available samples estimate time duration ensuing PCR amplification. Here, we demonstrate that hair urine can also become alternate source for reliably obtaining a small PCR-ready DNA. We developed rapid, cost-effective, noninvasive method sample collection simple extraction swabs, urine,...
Bacteria present in cave often survive by modifying their metabolic pathway or other mechanism. Understanding these adopted bacteria and survival strategy inside the is an important aspect of microbial ecology. Present study focuses on bacterial community geochemistry five caves Mizoram, Northeast India. The objective this was to explore taxonomic composition presumed functional diversity sediment metagenomes using paired end Illumina sequencing V3 region 16S rRNA gene bioinformatics...
With the advent of next-generation sequencing, large-scale initiatives for mining whole genomes and exomes have been employed to better understand global or population-level genetic architecture. India encompasses more than 17% world population with extensive diversity, but is under-represented in sequencing datasets. This gave us impetus perform analyze genome 1029 healthy Indian individuals under pilot phase 'IndiGen' program. We generated a compendium 55,898,122 single allelic variants...
Plants have been used since ancient times as an important source of biologically active substances. The aim the present study was to investigate phytochemical constituents (flavonoids and phenolics), antioxidant potential, cytotoxicity against HepG2 (human hepato carcinoma) cancer cell lines antimicrobial activity methanol extract selected traditional medicinal plants collected from Mizoram, India. A number phenolic compounds were detected using HPLC-DAD-ESI-TOF-MS, mainly Luteolin,...
Bacterial and archaeal diversity of two alkaline Indian hot springs, Jakrem (Meghalaya) Yumthang (Sikkim), were studied. Thirteen major bacterial phyla identified which Firmicutes, Chloroflexi Thermi dominant in Proteobacteria Yumthang. The genera Clostridium, Chloroflexus Meiothermus at (water temperature 46 °C, pH 9) Thiobacillus, Sulfuritalea 39 8) springs. four Euryarchaeota taxa that observed both the springs Methanoculleus, Methanosaeta, Methanosarcina Methanocorposculum. Elstera...
The current study focuses on developing a tumour-targeted functionalised nanocarrier that wraps hollow mesoporous silica nanoparticles. guanidine carbonate and curcumin are immobilised the surface of 3-aminopropyl-triethoxy silane (APTES)-decorated nanoparticles (HMSNP), as confirmed through XPS NMR analysis. analysis demonstrates shape hysteresis loops is modified pore volume diameter consequently decreased compared to control. Guanidine (85%) guanidine-curcumin complex (90%) were...
Research of natural products from traditionally used medicinal plants to fight against the human ailments is fetching attention researchers worldwide. Bidens pilosa Linn. var. Radiata (Asteraceae) well known for its folkloric use various diseases many decades. Mizoram, North East India, has high plant diversity and this as herbal medicine deep rooted in local tribes. The present study was executed understand pharmacological potential B. leaves extract.The antimicrobial determined using agar...
Highly pathogenic influenza A virus (HPAIV) continues to pose a pandemic threat globally. From 2003 2017, H5N1 HPAIV caused 453 human deaths, giving it high mortality rate (52.74%). This work shows that miR-324-5p suppresses replication by directly targeting the viral genome (thereby inhibiting gene expression) and cellular CUEDC2 gene, negative regulator of interferon pathway enhancing antiviral genes). Our study enhances knowledge role microRNAs in response infection. Also, provides help...
Protein kinase B (Akt) plays a very significant role in various cancers including oral cancer. However, it has three isoforms (Akt1, Akt2, and Akt3) they perform distinct functions even play contrasting roles different cancers. Therefore, becomes essential to evaluate the isoform-specific of Akt In present study, an attempt been made elucidate The immunohistochemical analysis cancer tissues showed overexpression Akt1 2 but not Akt3. Moreover, dataset "The Cancer Genome Atlas" for head neck...
The functional consequences of circular RNA (circRNA) expression on HIV-1 replication are largely unknown. Using a customized protocol involving direct nanopore sequencing, here, we captured circRNAs from HIV-1-infected T cells and identified ciTRAN, circRNA that modulates transcription. We found infection induces ciTRAN in Vpr-dependent manner interacts with SRSF1, protein known to repress Our results suggest hijacks exclude serine/arginine-rich splicing factor 1 (SRSF1) the viral...