A5054653801- Bipolar Disorder and Treatment
- Statistical Methods and Inference
- Schizophrenia research and treatment
- Statistical Methods and Bayesian Inference
- Healthcare professionals’ stress and burnout
- Diet and metabolism studies
- Child and Adolescent Psychosocial and Emotional Development
- Treatment of Major Depression
- Personality Disorders and Psychopathology
- Psychotherapy Techniques and Applications
- Advanced Causal Inference Techniques
- Mental Health Research Topics
- Stress and Burnout Research
- Maternal Mental Health During Pregnancy and Postpartum
- Sleep and related disorders
- Innovations in Medical Education
- Musculoskeletal pain and rehabilitation
- Neuroendocrine regulation and behavior
- Political Economy and Marxism
- Workplace Health and Well-being
- Attachment and Relationship Dynamics
- Economic Theory and Policy
- Income, Poverty, and Inequality
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 epidemiological studies
University of Lausanne
2021-2025
University Hospital of Lausanne
2023
University of Geneva
2013-2015
International Labour Organization
2013
Abstract Using household and labour force survey data from 11 developing countries, the authors calculate rates of minimum wage compliance for formal/informal employees covered by current legislation assess average “depth” violations. Though is negatively related to ratio median wages, countries with a national set at meaningful level typically achieve higher than occupational or industry‐specific systems. However, better – especially women, ethnic groups, unskilled informal workers also...
Background Medical students’ rate of depression, suicidal ideation, anxiety, and burnout have been shown to be higher than those the same-age general population. However, longitudinal studies spanning whole course medical school are scarce present contradictory findings. This study aims analyze evolution mental health from first last year using a wide range indicators. Moreover, biopsychosocial covariates that can influence this explored. Method In an open cohort design, 3066 annual...
Abstract: Previous research has unveiled an intriguing positive association between the AB blood group and mental disorders in general. In this study, we compared ABO groups with five major of to attain a higher level specificity. The analyses were conducted using data from CoLaus|PsyCoLaus study (N=5111). They revealed that exhibited both neurodevelopmental (RR 2.29, CI 1.38– 3.82) substance use 2.25, 3.65) after adjusting for sex childhood adversities. These associations could be...
Abstract Background The atypical antipsychotics risperidone and aripiprazole are metabolized by the cytochrome P450 2D6 (CYP2D6), as ~20% of currently prescribed medications. According to enzyme level activity, individuals can be categorized ultrarapid, normal, intermediate, or poor (UM, NM, IM PM, respectively) CYP2D6 metabolizers. Greater odds switching from within one year after last therapeutic drug monitoring were previously reported among PM UM while no differences observed for between...
Job stability - encompassing secure contracts, adequate wages, social benefits, and career opportunities is a critical determinant in reducing monetary poverty, as it provides households with reliable income enhances economic well-being. This study leverages EU-SILC survey census data to estimate the causal effect of job on poverty across Italian provinces, quantifying its influence analyzing regional disparities. We introduce novel small area estimation (CSAE) framework that integrates...
Emotion regulation (ER) is a key competence in adolescence that related to multiple psychological outcomes, including adaptive functioning and psychopathological symptoms. The development of ER skills closely associated with child’s family relational context. Nevertheless, few studies have investigated the physiological adolescents during interactions go beyond mother–adolescent dyad. Thus, little understood regarding which features communication mother–father–adolescent triad (e.g., warmth...
Metabolic abnormalities have been associated with olanzapine treatment. We assessed if has dose-dependent effects on metabolic parameters changes for weight, blood pressure, lipid and glucose profiles being modelled using linear mixed-effects models. The risk of including early weight gain (EWG) (≥5% during first month) was logistic regression In 392 olanzapine-treated patients (median age 38.0 years, interquartile range [IQR] = 26.0-53.3, median dose 10.0 mg/day, IQR 5.0-10.0 a follow-up...
Sleep disturbances are well-known symptoms of major depressive disorder (MDD). However, the prospective risk MDD in presence sleep a general population-based cohort is not well known. This study investigated associations between both polysomnography (PSG)-based or subjective features and incident MDD. Participants representative population who had never completed questionnaires (n = 2000) and/or underwent PSG 717). Over 8 years' follow-up, participants psychiatric interviews enabling...
Antipsychotic-induced metabolic adverse effects are risk factors for cardiometabolic comorbidities. Whether dose lowering could mitigate such remains unclear. The present study aims to investigate the associations between clozapine doses and modifications of weight, blood pressure, glucose, lipid levels.Linear mixed-effects models weight changes over 1 year variations other parameters 4 months were applied a prospective cohort 115 patients. Age- sex-stratified analyses also performed.Each...
Abstract Study objectives Insomnia disorders as well cardiometabolic are highly prevalent in the psychiatric population compared to general population. We aimed investigate their association and evolution over time a Swiss cohort. Methods Data for 2861 patients (8954 observations) were obtained from two prospective cohorts (PsyMetab PsyClin) with metabolic parameters monitored routinely during psychotropic treatment. based on presence of ICD-10 “F51.0" diagnosis (non-organic insomnia),...
Objective The present paper focuses on therapist responsiveness during the initial therapy session with clients borderline personality disorder (BPD), aiming to analyze at short intervals and determine if it can predict therapeutic alliance from both client viewpoints.
Weight gain, blood lipids and/or glucose dysregulation can follow aripiprazole treatment onset. Whether dosage is associated with an increase in these metabolic parameters remains uncertain. The present study investigates dose associations weight change, glucose, lipids, and pressure.
Chronic pain (CP) is often accompanied by mental disorders (MDs). However, little known concerning the long-term effect of MDs, personality traits, and early-life traumatic events (ETEs) on CP course. Accordingly, we aimed to prospectively assess associations major depressive (MDDs), anxiety disorders, ETEs with incidence persistence in middle-aged older community dwellers. Data stemmed from 3 first follow-up evaluations CoLaus|PsyCoLaus, a prospective cohort conducted general population...
Introduction In this study, we aimed to examine the association between aggressive ideations and behaviors in everyday life, as well role of processes related self-regulatory control (i.e., self-control, ego depletion, emotional states), using experience sampling methods (ESM). Methods A total 62 male adolescents performed a baseline measure aggression, violent (trait level), ESM assessments, including four measures per day during nine consecutive days. Results At state level, were...
Background Psychiatric patients are at high risk of readmission, and a body mass index has previously been shown as factor. We sought to replicate this finding 1) prospectively assess the association metabolic syndrome its five components with readmission in psychiatric hospitals 2) identify other clinical sociodemographic predictors readmission. Methods Between 2007 2019, data on 16727 admissions 7786 adult elderly admitted Department Psychiatry Lausanne University Hospital, were collected....
The aim of this study was to evaluate valproate dose association with weight change, blood glucose, lipid levels, and pressure in a psychiatric population.
Self-reported caffeine consumption has been widely used in research while it may be subject to bias. We sought investigate the associations between self-reported and plasma levels of its two main metabolites (paraxanthine theophylline) community.
Weight-inducing psychotropic treatments are risk factors for age-related diseases such as cardiovascular disorders, which associated with both inflammation and telomere length shortening. With a longitudinal design, the present study evaluates trajectories after 1 year of weight-inducing medication, accounting weight changes inflammatory biomarker high-sensitivity C-Reactive Protein (CRP). Among 200 patients, an overall median shortening -41.2 bp was observed (p = 0.014), is comparable...
Case formulation is a central tool for psychotherapists, which helps them tailor psychotherapy to the individual patient, particularly treatments complex and multilayered clinical problems, such as personality disorders (Kramer, 2019). methodologies are still underutilized in research prediction of therapy processes. The present study included N = 60 patients with borderline disorder undergoing brief treatment using an individualized component (n 31), compared standard 29; Kramer et al.,...
Objectives: To prospectively investigate the association between Effort-Reward Imbalance (ERI) and over-commitment scores of burnout dimensions over a 4 years follow-up period considering potential confounders. Methods: Data stemmed from CoLaus|PsyCoLaus, population-based cohort study including 575 participants (mean age 55 years, 50% men). Participants completed Maslach Burnout Inventory-General Survey, ERI questionnaires at baseline (T1) after (T2), provided demographic, behavioral,...
Resumen A partir de datos estadísticos, los autores analizan la cobertura del salario mínimo en once países desarrollo, su grado incumplimiento y brecha salarial derivada este, tanto para trabajadores formales como informales. Observan que con nacional (aun a buen nivel relación mediana salarial) obtienen mejor cumplimiento aquellos salarios mínimos múltiples por ocupación sector. Abogan además políticas amplias sensibilización control participación interlocutores sociales fin afrontar...
Minimum wages can be a powerful tool for supporting decent work goals and crucial component to the strengthening of social protection floors poverty alleviation efforts. This paper argues that effectiveness minimum depends on three aspects: first, legal coverage wage systems; second, level at which are set; third, ability ensure compliance with provisions, so as goal improving incomes reducing inequality.
Résumé. Les auteurs observent la couverture et le respect de législation sur salaire minimum dans onze pays en développement. Ils mettent relation l'étendue cette degré ce avec niveau du minimum, l'existence d'un taux unique ou multiples façon dont il est fixé mis application. La sont supérieurs, optimal atteint, lorsque système simple bien connu, que les travailleurs employeurs associés à fixation son