A5032540347- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- ECG Monitoring and Analysis
- Venous Thromboembolism Diagnosis and Management
- Advanced MRI Techniques and Applications
- Cardiovascular Function and Risk Factors
- Sarcoidosis and Beryllium Toxicity Research
- Heart Rate Variability and Autonomic Control
- Cardiac Fibrosis and Remodeling
- Cancer Risks and Factors
- Cardiovascular Disease and Adiposity
- Neurological disorders and treatments
- Extracellular vesicles in disease
- Ocular and Laser Science Research
- Telemedicine and Telehealth Implementation
- Takotsubo Cardiomyopathy and Associated Phenomena
- Peripheral Neuropathies and Disorders
- Single-cell and spatial transcriptomics
- Antibiotics Pharmacokinetics and Efficacy
- Metabolism, Diabetes, and Cancer
- Diabetes Treatment and Management
Kobe University
2019-2025
Okinawa Red Cross Hospital
2025
Universitair Ziekenhuis Brussel
2024-2025
Vrije Universiteit Brussel
2023-2025
Kitano Hospital
2016-2018
Uji Hospital
2018
Yodogawa Christian Hospital
2016
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
1970
Abstract Aims Pulsed field ablation (PFA) has emerged as a novel, non-thermal energy source to selectively ablate cardiac tissue. We describe multicentre experience on pulmonary vein isolation (PVI) via the pentaspline Farapulse™ PFA system vs. thermal-based technologies in propensity score-matched population of paroxysmal atrial fibrillation (PAF) patients. Methods and results Propensity score matching was adopted compare PVI-only outcomes Farawave™ (Group PFA), cryoballoon CRYO), or focal...
BACKGROUND: Pulsed field ablation (PFA) is a novel technology for catheter-based atrial arrhythmia treatment. Evidence of its application ventricular still limited. In this study, we describe the feasibility and efficacy focal PFA premature contraction (PVC) ablation. METHODS: A prospective cohort 20 patients referred PVC at 2 centers was enrolled, regardless presence structural heart disease, morphology, or previous attempts. All procedures were performed using CENTAURI System in...
Abstract The areas with electrically fractionated potentials (AEFP) during sinus rhythm are related to non-pulmonary vein triggers and may serve as substrates of atrial fibrillation (AF) maintenance. However, the histological properties these compounds remain unclear. Therefore, we aimed evaluate late gadolinium enhancement (LGE) AEFP in patients AF. We enrolled 15 AF who had undergone LGE magnetic resonance imaging before catheter ablation. left atrium was detected using HD-Grid NavX...
Background Effective balloon positionnking during pulmonary vein isolation (PVI) with a radiofrequency (RFB) is crucial for optimal energy delivery, maximising lesion formation, and preventing gaps. Traditionally, fluoroscopy used to guide (PV) occlusion, however, this method exposes patients radiation. Recently, RFBs equipped 3D electroanatomical mapping (EAM) offer an alternative approach, potentially achieving the same results reduced radiation exposure. Our main aim was evaluate...
ABSTRACT Introduction The extensive use of pulsed field ablation (PFA) in clinical settings has unveiled new evidence suggesting potential involvement red blood cell structural impairment resulting hemolysis and acute kidney injury (AKI). Methods In this study, samples were collected from 16 patients before 24 h after pulmonary vein isolation (PVI) via a novel investigational PFA‐based technology. Biochemical analyses performed to assess AKI, including total indirect bilirubin, lactate...
Abstract Background and Aims Rhythm control of non-paroxysmal atrial fibrillation (AF) is significantly more challenging, as a result arrhythmia perpetuation promoting substrate changes AF maintenance. We describe tailored ablation strategy targeting multiple left (LA) sites via pentaspline pulsed field (PFA) catheter in persistent sustained beyond 6 months (PerAF>6m) long-standing (LSPAF). Methods The protocol included the following stages: pulmonary vein antral posterior wall...
Several algorithms have been proposed for differentiating the right and left outflow tracts (RVOT/LVOT) arrhythmia origins from 12-lead electrocardiograms (ECGs); however, procedure is complicated. A deep learning (DL) model, a form of artificial intelligence, can directly use ECGs depict importance leads waveforms. This study aimed to create visualized DL model that could classify more accurately.
Abstract Background A computational model demonstrated that atrial fibrillation (AF) rotors could be distributed in patchy late‐gadolinium enhancement (LGE) areas and play an important role AF drivers. However, this was not validated humans. Objective The purpose of study to evaluate the LGE properties patients with persistent AF. Methods total 287 segments 15 (long‐standing 9 patients) underwent ablation were assessed. Non‐passively activated (NPAs), where rotational activation (AF rotor)...
Atrial fibrillation (AF) is strongly associated with strokes, heart failure, and increased mortality. This study aims to identify the monocyte–macrophage heterogeneity interactions of these cells non-immune cells, functional biomarkers in patients AF. Therefore, we assess single cell landscape left atria (LA), using a combination nucleus RNA-seq. Myeloid LA tissue are categorized into five macrophage clusters, three monocyte others. Cell-Chat analysis revealed that monocytes IL1B+...
Some of atrial fibrillation (AF) drivers are found in normal/mild late-gadolinium enhancement (LGE) areas, as well moderate ones. The wall thickness (AWT) has been reported to be important a possible AF substrate. However, the AWT and degree LGEs an substrate not fully validated humans.
The skin overlying cardiovascular implantable electronic devices (CIEDs) sometimes becomes very thin after implantations, which could cause a device erosion. factors related to the thickness of pockets have not been elucidated. This study aimed evaluate CIED and search for associated with thickness.Seventeen points around pocket were measured through ultrasonography in each patient.A total 101 patients (76 ± 11 years, 26 female) enrolled. median duration from implantation examination was 95...
Background Medium-dose (25 gray) x-ray radiation therapy has recently been performed on patients with refractory ventricular tachyarrhythmias. Unlike x-ray, carbon ion and proton beam can deliver most of their energy to the target tissues. This study investigated electrophysiological pathological changes caused by medium-dose in left ventricle (LV). Methods Results External whole LV was 32 rabbits. A total 9 rabbits were not irradiated (control). At 3-month or 6-month follow-up, animals...
Abstract A 41‐year‐old man with persistent atrial fibrillation (AF) underwent radiofrequency (RF) catheter ablation using an online real‐time phase mapping system: ExTRa Mapping. Box isolation could not terminate AF. Subsequently, RF applications on nonpassively activated areas (NPAs), where rotational activations were frequently observed, at the posterior bottom of left atrium outside box lesion convert AF to common flutter. Of interest, NPA near located patchy fibrotic tissue area assessed...
A computer simulation model has demonstrated that atrial fibrillation (AF) driver can be attached to heterogeneous fibrosis assessed by late gadolinium enhancement magnetic resonance imaging (LGE-MRI). However, it not been well elucidated in patients with persistent AF. The aim of this study was investigate whether radiofrequency (RF) applications the fragmented LGE area (FLA) could terminate AF or convert tachycardia (AT) and improve rhythm outcome.A total 31 consecutive FLAs were enrolled...
Abstract Background Inflammation, such as that associated with intermediate CD14 ++ CD16 + monocytes and atrial structural remodeling (SRM), may be important in the recurrence of fibrillation (AF) after catheter ablation. However, relationship between monocytes, SRM, AF is unclear. Methods Twenty‐four patients were enrolled. The proportion (PIM) was assessed before ablation by flow cytometry. As a surrogate marker volume ratio (VR) signal intensity greater than 1 standard deviation on...
Abstract Knowing the vascular anatomy of common femoral artery bifurcation and ultrasound‐guided puncture, including doppler, is helpful in recognizing anatomic variations avoiding complications.
Abstract We described an elderly man with neuromyelitis optica spectrum disorder (NMOSD) causing sick sinus syndrome (SSS) following intractable hiccups caused by area postrema (APS). He had multiple cardiovascular risk factors including coronary angina, diabetes mellitus, hyperlipidemia, and smoking history. His SSS resolved the disappearance of hiccups. Clinicians should be aware that severe bradyarrhythmia could associated APS, especially in NMOSD patients.
Background:Demand is growing for remote electrocardiogram (ECG) monitoring systems in the COVID-19 era Japan. This study describes initial experiences with a small wireless ECG device and utility of delivery via postal service outpatient care
The mechanism underlying the sex differences in atrial fibrillation (AF) recurrence following pulmonary vein (PV) isolation is not fully understood. We hypothesized that non-PV foci and epicardial adipose tissue (EAT) play a key role.
Introduction: In the COVID-19 era, demand is growing for remote ECG monitoring systems with less or no in-person contact. However, practical usage of wearable devices has been little studied in Japan. This study aimed to report our initial experience using postal system delivery self-wearable device (Duranta) and long-term outpatient care. Methods: The Duranta small, light (35 g), easy attach chest two patch electrodes. Real-time data were automatically transmitted a cloud server via...
Aims Corticosteroids are widely used in patients with cardiac sarcoidosis (CS). In addition, upgrading to resynchronization therapy (CRT) is sometimes needed. This study aimed investigate the impact of corticosteroid use on clinical outcomes following CRT upgrades. Methods A total 48 consecutive non-ischemic cardiomyopathies who underwent upgrades were retrospectively reviewed and divided into three groups: group 1 included CS taking corticosteroids before upgrade (n = 7), 2, not 10), 3,...