Xu Lanping

ORCID: 0000-0002-0272-0293
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Research Areas
  • Hematopoietic Stem Cell Transplantation
  • Acute Myeloid Leukemia Research
  • Acute Lymphoblastic Leukemia research
  • CAR-T cell therapy research
  • Chronic Myeloid Leukemia Treatments
  • Mesenchymal stem cell research
  • Eosinophilic Disorders and Syndromes
  • Immune Cell Function and Interaction
  • Chronic Lymphocytic Leukemia Research
  • Immune Response and Inflammation
  • Advancements in Semiconductor Devices and Circuit Design
  • Immunodeficiency and Autoimmune Disorders
  • Astro and Planetary Science
  • Immune cells in cancer
  • Transplantation: Methods and Outcomes
  • Autoimmune and Inflammatory Disorders Research
  • Herpesvirus Infections and Treatments
  • Parvovirus B19 Infection Studies
  • Cancer-related molecular mechanisms research
  • Astrophysics and Star Formation Studies
  • Stellar, planetary, and galactic studies
  • Ovarian function and disorders
  • Oral health in cancer treatment
  • Polyomavirus and related diseases
  • Integrated Circuits and Semiconductor Failure Analysis

Peking University
1988-2024

Peking University People's Hospital
2009-2024

National Clinical Research
2024

Gansu University of Traditional Chinese Medicine
2020

United States Government Accountability Office
2014

Renmin Hospital of Wuhan University
2009

Wuhan University
2009

The study aimed to compare the outcomes of patients undergoing hematopoietic stem cell transplantation (HSCT) from partially matched related donors (PMRD) and unrelated (URD) for hematologic malignancies without use in vitro T depletion.HSCT was done on 297 consecutive URDs (n = 78) PMRDs 219) during same time period. Incidences graft-versus-host disease (GVHD), relapse, nonrelapse mortality, overall survival, leukemia-free survival between PMRD URD groups were compared.All achieved full...

10.1158/1078-0432.ccr-09-0691 article EN Clinical Cancer Research 2009-07-08

Background. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the only proven curative therapy for chronic myeloid leukemia (CML), but lack of human leukocyte antigen (HLA)-matched sibling or unrelated donors has restricted its application. Recently, we developed an effective method haploidentical allo-HSCT achieving comparable outcomes to HLA-identical transplantation.Aim. To evaluate CML patients who underwent allo-HSCT.Methods. Ninety-three were treated with a...

10.1080/07853890801908903 article EN Annals of Medicine 2008-01-01

The purpose of this study is to define the role for allogeneic hematopoietic stem cell transplantation (allo‐HSCT) in mixed‐lineage‐leukemia (MLL)‐rearranged acute leukemia, which now poorly understood. A prospective, multi‐center cohort determine whether allo‐HSCT could decrease relapse rates and improve long‐term survival MLL+ leukemia patients was performed. Fifty‐six consecutive diagnosed with MLL–rearranged undergoing from two transplant centers China were enrolled between October 2007...

10.1002/ajh.23595 article EN American Journal of Hematology 2013-10-12

Background The effects of donor characteristics on CD34 + cell dose remain controversial. Recently, we developed a novel haploidentical transplant protocol, in which mixture allografts granulocyte colony-stimulating factor (G-CSF)-primed bone marrow (G-BM) and G-CSF-mobilized peripheral blood (G-PB) were used. aim this study was to investigate the G-BM G-PB. Methods A total 162 healthy adult donors, who underwent harvest collection between January 2009 November 2010 Peking University...

10.3760/cma.j.issn.0366-6999.20141161 article EN cc-by-nc-nd Chinese Medical Journal 2014-10-20

Rheumatoid arthritis (RA) is a worldwide autoimmune disease. The study of its aetiology and mechanism has always been focus topic in medicine. This research was designed to investigate the effect E3 ubiquitin ligase tripartite motif protein 32 (TRIM32) rheumatoid (RA). We found fibroblast-like synoviocytes (FLS) RA patients, expression TRIM32 significantly increased compared with osteoarthritis (OA) patients FLS. A widely used pro-inflammatory stimuli tumour necrosis factor-alpha (TNF-α)...

10.1111/sji.12876 article EN Scandinavian Journal of Immunology 2020-03-07

<title>Abstract</title> <bold>Aim: </bold>Epstein-Barr virus (EBV) is the important pathogen of infection after allogeneic hematopoietic stem cell transplantation (allo-HSCT), which also common cause secondary hemophagocytic lymphohistiocytosis (sHLH). Thus, we aimed to identify clinical manifestations and outcomes EBV-related sHLH allo-HSCT. <bold>Methods:</bold> We enrolled patients who experienced EBV DNAemia allo-HSCT from Jan 1<sup>st</sup>, 2023 Dec 31<sup>st</sup>, 2023. Plasma copies...

10.21203/rs.3.rs-4768158/v1 preprint EN cc-by Research Square (Research Square) 2024-08-26
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