A5035174799- COVID-19 Clinical Research Studies
- Trace Elements in Health
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and healthcare impacts
- Plant responses to water stress
- Coffee research and impacts
- Tuberculosis Research and Epidemiology
- Diphtheria, Corynebacterium, and Tetanus
- Infective Endocarditis Diagnosis and Management
- Plant nutrient uptake and metabolism
- Aldose Reductase and Taurine
- Diagnosis and treatment of tuberculosis
- Magnesium Oxide Properties and Applications
- Bacterial Identification and Susceptibility Testing
- Body Composition Measurement Techniques
- Respiratory Support and Mechanisms
- Takotsubo Cardiomyopathy and Associated Phenomena
- Botulinum Toxin and Related Neurological Disorders
- Advanced Data Storage Technologies
- Pericarditis and Cardiac Tamponade
- Infectious Encephalopathies and Encephalitis
- SARS-CoV-2 detection and testing
- Innovations in Medical Education
- Vitamin D Research Studies
Community Medical Center
2021-2024
University of Leeds
2024
Rutgers, The State University of New Jersey
2022-2024
National University of Sciences and Technology
2023-2024
Manchester University NHS Foundation Trust
2021-2024
King Edward Medical University
2023
International Centre for Genetic Engineering and Biotechnology
2021-2023
Manchester Royal Infirmary
2021
Medical University of South Carolina
1993
Zn 2+ binds to the active site of SARS-CoV-2 main protease (Mpro), and inhibits enzyme activity viral replication in vitro .
Ceramics are the oxides of metals and nonmetals with excellent compressive strength. usually exhibit inert behavior at high temperatures. Magnesium aluminate (MgAl 2 O 4 ), a member ceramic family, possesses working temperature up to 2000°C, low thermal conductivity, strength even elevated temperatures, good corrosion resistance. Moreover, Aluminate Nanoparticles (MANPs) can be used in making refractory crucible applications. This study focuses on their application crucibles. The molten salt...
Background: Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide, placing a significant burden on healthcare systems. The emergence high-sensitivity cardiac troponin (hs-Tn), biomarker for myocardial injury, offers new potential in improving cardiovascular risk prediction, particularly asymptomatic individuals with subclinical atherosclerosis. This advancement addresses critical gaps traditional stratification models promotes early detection...
Abstract The sugar will eventually be exported transporter (SWEET) members in Arabidopsis, AtSWEET11 and AtSWEET12 are the important sucrose efflux transporters that act synergistically to perform distinct physiological roles. These two involved apoplasmic phloem loading, seed filling, level alteration at site of pathogen infection. Here, we performed structural analysis binding pocket using molecular docking followed by rigorous dynamics (MD) simulations. We observed molecule binds inside...
<h3>Introduction</h3> There is little described in the current COVID-19 literature about outcomes of patients discharged from hospital following pneumonia. We describe rapid establishment a 'virtual ward' (VW) for follow-up with suspected or confirmed diagnosis pneumonia pneumonitis upon discharge, characteristics and first 300 patient referrals. <h3>Methods</h3> Admitted confirmed/suspected pneumonia/pneumonitis were referred electronically to VW on discharge. Pulse oximeters provided if...
We previously reported that cell cultures of human proximal tubule (HPT) cells respond to ionic cadmium in a manner consistent with well-defined Cd(2+)-elicited responses for vivo systems. However, one unique finding was the transepithelial electrical resistance and tight junction sealing strands were altered as result Cd2+ exposure at micromolar concentrations. These alterations are reexamined detail present report determine whether Cd(2+)-induced specific structure or reflect general...
Abstract Sugar will eventually be exported transporters (SWEETs) have been identified as a unique class of sugar efflux in all biological kingdoms. AtSWEET11 and AtSWEET12 Arabidopsis act synergistically to perform distinct physiological roles, particularly apoplasmic phloem loading, seed filling, level alteration at the site pathogen infection. Plasma membrane-localized exclusively facilitate sucrose transport along concentration gradient. This article examines binding pocket using docking...
Qaiser, Saria; Valladares, Carlos; Rodriguez, Cristina; Luzuriaga, Adriana; Ang, Song; Khan, Wajahat Author Information
Abstract Zinc deficiency is linked to poor prognosis in COVID-19 patients while clinical trials with demonstrate better outcome. The molecular target and mechanistic details of anti-coronaviral activity remain obscure. We show that ionic not only inhibits SARS-CoV-2 main protease (Mpro) nanomolar affinity, but also viral replication. present the first crystal structure Mpro-Zn 2+ complex at 1.9 Å provide structural basis replication inhibition. Zn coordinates catalytic dyad enzyme active...
Our understanding of the severe acute respiratory syndrome coronavirus 2 has evolved since first reported cases in December 2019, and a greater emphasis been placed on hyper-inflammatory response severely ill patients. The purpose this study was to determine risk factors for mortality impact anti-inflammatory therapies survival.To various outcomes disease 2019 patients with focus immune-modulating agents.A retrospective analysis conducted 261 admitted or transferred intensive care unit two...
Introduction: Infectious endocarditis (IE) is a potentially fatal condition which becomes clinical challenge when the causing pathogen difficult to diagnose. Blood cultures remain standard diagnosing tool for guiding and optimizing antibiotic treatment, yet up 20% of cases can present with negative blood cultures. The following case report presents culture developing bilateral lower extremity ischemia right atrial thrombus encircling pacemaker lead. Description: A 78 year old male past...
Coronary artery disease is the most prevalent form of heart disease. It along with its complications are a leading cause morbidity and mortality among world population. bypass grafting done in significant (>50%) stenosis all major coronary trunks their branches. The burden atrial fibrillation varies from one population to another patients subjected CABG. OBJECTIVE: To determine frequency after grafting. MATERIALS AND METHODS: This Descriptive cross-sectional study was conducted...
Caffeinated energy drinks (EDs) consumers are mostly unaware of the side effects due to long term use excess amount caffeine. Excess caffeine content in ED brands is not that much concerned public health issue Bangladesh perspective. A two-part study was conducted determine quantitative profile used most popular EDs available Bangladesh, as well frequency usage and popularity among its young educated customers’ segment. UV-Visible spectroscopy (UV 1800 Spectrophotometer, Shimadz, Kyoto,...
<h3>Introduction</h3> In wave 2 of the pandemic, Virtual COVID Ward (VCW) was expanded to include Emergency Department (ED) as well ward discharges with pneumonitis. Outcomes ED patients have been reviewed and key recommendations drawn inform practice in endemic phase COVID. <h3>Methods</h3> A retrospective review persons attending who were not admitted illness (COVNA) undertaken assess safety clinical effectiveness VCW between 01/10/2020–01/04/21. Demographic data collected outcomes...