A5033231789- Sinusitis and nasal conditions
- Obstructive Sleep Apnea Research
- Head and Neck Surgical Oncology
- Nasal Surgery and Airway Studies
- Tracheal and airway disorders
- Neuroscience of respiration and sleep
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Dysphagia Assessment and Management
- Pediatric health and respiratory diseases
- Head and Neck Cancer Studies
- Infectious Diseases and Mycology
- Mycobacterium research and diagnosis
- Voice and Speech Disorders
- Oral and Maxillofacial Pathology
- Sleep and Wakefulness Research
- Cleft Lip and Palate Research
- Salivary Gland Tumors Diagnosis and Treatment
- Meningioma and schwannoma management
- Reconstructive Surgery and Microvascular Techniques
- Cancer Diagnosis and Treatment
- Viral-associated cancers and disorders
- Clinical practice guidelines implementation
- Soft tissue tumor case studies
- Autoimmune and Inflammatory Disorders
University of California, San Francisco
2016-2025
Hospital Universitario Doctor Peset
2024
Ibero American University
2020
John Wiley & Sons (United States)
2016
Neurological Surgery
2015
Nashville Oncology Associates
2014
The University of Texas at Austin
2012
University of San Francisco
2008
Center for Clinical Research (United States)
2006
Seattle University
2006
Enrichment of Corynebacterium tuberculostearicum caused by depletion the sinus microbiome contributes to chronic rhinosinusitis.
To determine the interrater reliability of drug-induced sleep endoscopy (DISE).Prospective cohort; blinded comparison.Academic referral center.Subjects with obstructive apnea unable to tolerate positive airway pressure therapy.Drug-induced was performed intravenous propofol infusion achieve sedation, and videoendoscopy recording evaluated by 2 independent reviewers.The following outcomes were measured: a global assessment obstruction at palate and/or hypopharynx; degree contribution...
OBJECTIVE The aim of this study was to further evaluate the safety and effectiveness balloon catheter devices dilate obstructed sinus ostia/perform sinusotomy. METHODS Through a prospective, multicenter evaluation, assessed by rate adverse events, patency determined endoscopic examination, symptoms were Sino‐Nasal Outcome Test (SNOT 20). RESULTS At conclusion 24‐week analysis, endoscopy that sinusotomy patent in 80.5% (247 307) sinuses nonpatent 1.6% (5 307), could not determine ostial...
To determine the test-retest reliability of drug-induced sleep endoscopy (DISE).Prospective cohort study. Patients with OSA underwent two separate DISE examinations. The following outcomes were measured: a global assessment obstruction at palate and/or hypopharynx; degree and contribution individual structures (palate, tonsils, tongue, epiglottis, lateral pharyngeal walls) to obstruction.Thirty-two patients preoperative study apnea-hypopnea index was 40.7 +/- 21.1, lowest oxygen saturation...
PURPOSE: To determine the value of magnetic resonance (MR) imaging in predicting resectability head and neck neoplasms around carotid arteries. MATERIALS AND METHODS: Forty-nine patients (28 male 21 female aged 17-79 years; mean, 57.3 years) with masses clinical evidence wall invasion underwent MR imaging. T1-weighted, T2-weighted, gadolinium-enhanced T1-weighted images were analyzed to circumferential involvement 53 arteries by tumor. RESULTS: More than 270 degrees was considered suggestive...
Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by persistent sinonasal inflammation and sinus microbiome dysbiosis. The basis of this heterogeneity poorly understood. We sought to address the hypothesis that limited number compositionally distinct pathogenic bacterial microbiota exist in CRS patients invoke discrete immune responses clinical phenotypes patients. Sinus brushings from with (n = 59) healthy individuals 10) collected during endoscopic surgery were analyzed...
<h3>Importance</h3> Despite the significant contribution of surgical spending to health care costs, most surgeons are unaware their operating room costs. <h3>Objective</h3> To examine association between providing with individualized cost feedback and supply costs in room. <h3>Design, Setting, Participants</h3> The OR Surgical Cost Reduction (OR SCORE) project was a single–health system, multihospital, multidepartmental prospective controlled study an urban academic setting. Intervention...
Study 1: To assess the oncologic outcome following supracricoid partial laryngectomy (SCPL). 2: compare quality of life (QOL) SCPL to total (TL) with tracheoesophageal puncture (TEP). 3: analyze whole organ TL sections determine percentage lesions amenable STUDY DESIGN: A retrospective review patients who underwent SCPL. non-randomized, prospective study using QOL instruments either or histopathologic specimens assessed for possibility performing an SCPL.Study Twenty-five carcinoma larynx...
Chronic type 2 (T2) inflammatory diseases of the respiratory tract are characterized by mucus overproduction and disordered mucociliary function, which largely attributed to effects IL-13 on common epithelial cell types (mucus secretory ciliated cells). The role rare cells in airway T2 inflammation is less clear, though tuft have been shown be critical initiation immunity intestine. Using bulk single-cell RNA sequencing epithelium mouse modeling, we found that expanded programmed toward...
Epithelial remodeling is a histopathologic feature of chronic inflammatory airway diseases including rhinosinusitis (CRS). Cell-type shifts and their relationship to CRS endotypes severity are incompletely described.
Since 1992, 42 patients at the University of Pennsylvania have been treated for inverted papilloma (IP). Thirty-three were managed endoscopically with or without a Caldwell Luc approach (CLA) and retrospectively analyzed. The CLA, which involves gingivobuccal incision access to maxillary sinus, is distinguished from formal procedure. These 33 histologically confirmed IP evidence malignancy. They also did not intracranial, orbital, frontal sinus IP. Seventeen (17/33) prior treatment...
Endoscopic and radiological findings in patients with chronic sinusitis do not always correlate symptoms. Studies suggest that postoperative endoscopic examination of the sinonasal cavity provides prognostic information regarding potential for future episodes need revision surgery. It is recommended on nasal endoscopy be included outcomes studies sinusitis.
The primary objective was to assess the long-term effectiveness of balloon catheter sinusotomy.Patients who had sinus ostia dilated with catheters were prospectively evaluated 1 year after surgery nasal endoscopy, a CT scan, and Sino-Nasal Outcome Test (SNOT-20).Sixty-six patients (202 sinuses) examined. One hundred seventy-two 202 (85%) endoscopically patent, percent (2/202) nonpatent, ostial patency could not be determined by endoscopy in 28 (14%). In these "indeterminate" sinuses, scans...
Treatment delays in the operative management of mandible fractures are often unavoidable. We were interested determining whether increased incidence complications these patients.A retrospective chart review was performed on all patients who presented to San Francisco General Hospital with an fracture 2002. On basis number days from initial injury surgery, divided into two groups: those repaired 3 or less and after days. The infectious technical then compared between groups. Substance abuse...
Objectives: Endoscopic technology is allowing larger resections of the anterior and middle skull base with resultant dural defects. A pedicled nasal septal flap (NSF) based on posterior artery has recently been developed for closure these We describe our initial experience NSF vascularized coverage Design: Retrospective review. Setting: Tertiary care center. Participants: Patients undergoing endoscopic harvest reconstruction. Results: Twenty-eight patients had 32 NSFs raised over 14 months...
To determine obstructive sleep apnea (OSA) surgical volume, types, costs, and trends. explore whether specific patient hospital characteristics are associated with the performance of isolated palate versus hypopharyngeal surgery costs.Cross-sectional study.Inpatient outpatient medical facilities in United States.OSA procedures were identified Healthcare Cost Utilization Project Nationwide Inpatient Sample for 2000, 2004, 2006 from State Ambulatory Surgery Databases four representative states...
Objective The use of expanded endonasal surgery (EES) in the treatment skull base neoplasms has increased significantly recent years. Since 2006, nasoseptal flap (NSF) become workhorse for closure defects involving anterior and central base. We hypothesized that defect site impacts rate cerebrospinal fluid (CSF) leak following EES. Study Design Retrospective cohort study. Setting/Subjects/Methods Patients who underwent repair using a NSF at University California San Francisco (UCSF)...