- Dental Implant Techniques and Outcomes
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Dental Radiography and Imaging
- Periodontal Regeneration and Treatments
- Dental materials and restorations
- Oral microbiology and periodontitis research
- Orthodontics and Dentofacial Orthopedics
- Titanium Alloys Microstructure and Properties
- Bone Metabolism and Diseases
- Mesenchymal stem cell research
- Polymer Surface Interaction Studies
- Sinusitis and nasal conditions
- Additive Manufacturing and 3D Printing Technologies
- Tissue Engineering and Regenerative Medicine
- Orthopedic Infections and Treatments
- Bone and Dental Protein Studies
- Dental Health and Care Utilization
- Reconstructive Surgery and Microvascular Techniques
- Advanced materials and composites
- Endodontics and Root Canal Treatments
- Temporomandibular Joint Disorders
- Salivary Gland Disorders and Functions
- Electrospun Nanofibers in Biomedical Applications
- Oral and gingival health research
Stomatology Hospital
2016-2025
Zhejiang University
2016-2025
Chambroad Chemical Industry Research Institute (China)
2021-2023
Guilin University of Technology
2023
Zhejiang University Medical College Affiliated Stomatological Hospital
2005-2022
Wuyi University
2018-2021
Indiana University School of Medicine
2018
Hangzhou Xixi hospital
2018
Qilu University of Technology
2015
Holland Bloorview Kids Rehabilitation Hospital
2011
Abstract Aim This retrospective study assessed the risk factors associated with early and late implant loss at patient‐ implant‐based analysis. Materials methods A total of 18,199 patients received 30,959 dental implants during years 2011–2015. Age, gender, jaw, location, brands, length diameter, bone augmentation procedures, number placed per patient were recorded. multivariate generalized estimating equation ( GEE ) logistic regression was used to identify related both loss. Results The...
Purpose: This review aims to summarize the available technologies, material categories, and prosthodontic applications of additive manufacturing (AM) dental ceramics, evaluate achievable accuracy mechanical properties in comparison with current mainstream computer-aided design/computer-aided (CAD/CAM) subtractive (SM) methods, discuss future prospects directions.
To determine the thickness of facial bone wall and sagittal angulation between long axis teeth associated alveolar in maxillary esthetic zone using cone beam computed tomography (CBCT).A retrospective radiographic study CBCT images was conducted 300 patients. The distance cementoenamel junction (CEJ) crest, (4 mm apical to CEJ midroot), angle respective were measured. Descriptive statistics frequency analyses performed.The sample included 133 men 167 women (mean age, 36.9 years; range, 18 60...
Abstract Objective The objective of this study was to compare magnesium‐substituted and pure hydroxyapatite coatings on the promotion osteogenesis in vitro osseointegration vivo . Methods Electrochemically deposited ( EDHA ) or electrochemically EDMHA were formed surface titanium disks implants. MC 3T3‐E1 preosteoblasts cultured coated disks, cell growth, alkaline phosphatase ALP activity, osteocalcin secretion measured at various time points. For studies osseointegration, 30 roughened...
MNT-Sr can promote rBMSC osteogenic differentiation and significantly enhance migration homing <italic>via</italic> activation of SDF-1α/CXCR4 signaling.
Strontium (Sr) has shown strong osteogenic potential and thereby been widely incorporated into dental orthopedic implants. However, the improved osseointegration of strontium-modified titanium implants through regulation angiogenesis macrophage polarization is still beginning to be explored. Here, we demonstrated that angiogenic capacity human umbilical vein endothelial cells on Sr-incorporated micro/nano (SLA-Sr) surface was also significantly up-regulated expression HIF-1α protein Erk1/2...
Antibiotics are often used to treat systemic diseases not associated with the oral cavity. This application of antibiotics may affect healthy microbiota community, as it destroys balance between specific bacterial populations throughout ecosystem and lead dysbacteriosis. We hypothesized that effects on regulation function would antibody content in saliva, depending antibiotic type. To address this, a total 24 Sprague Dawley rats (divided into 4 cages, 6 per pen) were administered amoxicillin...
To evaluate the outcomes of an apically repositioned flap (ARF) plus xenogeneic collagen matrix (XCM) in augmenting keratinized mucosa width (KMW) around dental implants when compared with ARF free gingival grafts (FGG).Twenty-six participants at least one site KMW ≤2 mm were randomized into FGG or XCM group. Clinical examinations performed baseline and 2 6 months after surgery, including KMW, thickness, index (GI), probing depth (PD). Post-operative pain patient satisfaction also...
Osseointegration seems to be a foreign body reaction equilibrium due the complicated interactions between immune and skeletal systems. The heterogeneity of osteoimmune microenvironment in osseointegration implant materials remains elusive. Here, single-cell study involving 40043 cells is conducted, total 10 distinct cell clusters are identified from five different groups. A preliminary description revealed diverse cellular dynamic changes modulated by properties. increased immature neutrophils, Ly6C
The requirement for bone grafts needed filling defect and fracture is increasing annually due to global ageing a great amount of trauma cases, whereas the conventional bioceramic implants suboptimal regeneration inconvenient implantation operation. Here we describe 3D printed granule-type bioceramics evaluate porous architectures biological performances two types Mg-mediating silicate bioceramics. 6 % 9 Mg doped wollastonite (CSi-6 CSi-9) pure or Mg-rich akermanite (AKT AKT-9) granules had...
Monolithic zirconia crowns fabricated using computer-aided design and manufacturing (CAD-CAM) via subtractive (SM) exhibit limited bonding properties compared with other ceramics. Traditional methods such as air abrasion can improve but may negatively affect the mechanical stability of zirconia. Nanoparticle jetting (NPJ), an emerging 3-dimensional–printing technology for restorations, offers potential to create intricate structures, porous surfaces, high precision. This study aimed...
Based on research into bionic butterflies for environmental detection and ecological management, a scheme was proposed to develop manufacture aircraft with two wings inspired by specific butterfly species. A flapping-wing simple structure designed, its two-wing design optimized. The focused several key areas: the optimization of wings, development transmission mechanism, hardware fabrication, 3D printing component manufacturing. This resulted in replication wing shape Tiger Papilio...
This study aimed to evaluate the accuracy of ultrasonic jaw tracking system by comparing with conventional electronic in recording condylar movements. Twenty-six subjects normal occlusion participated study. The CADIAX® 4 and Jaw Motion Analyzer (JMA) systems were used record movement trajectories during mandibular border movements (protrusive/retrusive, lateral, wide mouth opening), each repeated three times. Both facebows sensors locate axis points capture trajectory data. Paired t-tests...
To investigate the effects of patient-related factors such as age, sex, implant location, and history periodontitis, on crestal bone loss in posterior region throughout surgical healing functional periods. This study evaluated 311 implants from 163 patients, with an average follow-up 27.10 months. Implants were assessed based periodontitis. Crestal was quantified by measuring level changes using oral panoramic radiographs. Time T1 defined period placement to phase, T2 second-stage surgery...
ABSTRACT Objectives To evaluate the 1‐ to 5‐year outcomes of dental implants placed with tenting screw (TS) technique and compare their clinical efficacy conventional guided bone regeneration (GBR). Methods This retrospective study involved TS or GBR technique. Horizontal volumetric gains were evaluated by reconstructing cone‐beam computed tomography (CBCT) data. Complications, biological parameters, esthetic scores, patients' satisfaction recorded. Results A total 75 in 42 patients (20...
The decreased bone density and increased marrow adiposity that occur with aging may influence the outcome of dental implants. Strontium (Sr), an anabolic agent for treatment osteoporosis, has inhibitory effect on adipogenesis but favors osteogenesis marrow–derived mesenchymal stem cells (BMSCs). However, little is known about effects mechanisms local Sr release during formation in aged bone. In this study, a potential implant material, Sr-doped titanium, was developed via sandblasted,...
The present study investigated the role of nitric oxide (NO) signaling pathway in progression periodontal disease, and explored related genetic mechanisms. An experimental model periodontitis was established Sprague‑Dawley rats, then they were divided into normal control, 2, 4 6 weeks post‑surgery groups. NO content determined saliva rats from each group by Griess reagent method. Pathological changes tissue sections evaluated with hematoxylin‑eosin staining. also immunohistochemistry to...
Aim: To characterize the profile of submucosal microbiome and cytokine levels in peri-implant crevicular fluid (PICF) from clinically healthy implants peri-implantitis same individuals. Material Methods: A total 170 patients were screened and, finally, 14 with at least one implant included. Submucosal microbiota cytokines 28 analyzed using 16S rRNA gene sequencing multifactor assays, respectively. Correlations clinical indexes or Spearman’s correlation coefficient. random forest...