Hui Luo

ORCID: 0000-0002-0325-2620
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About
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Research Areas
  • Photoacoustic and Ultrasonic Imaging
  • Cancer-related molecular mechanisms research
  • Plant-derived Lignans Synthesis and Bioactivity
  • Venous Thromboembolism Diagnosis and Management
  • Phonocardiography and Auscultation Techniques
  • Virus-based gene therapy research
  • Non-Invasive Vital Sign Monitoring
  • Ultrasound and Cavitation Phenomena
  • Cancer Research and Treatments
  • RNA Research and Splicing
  • Biomarkers in Disease Mechanisms
  • Synthesis and biological activity
  • RNA modifications and cancer
  • ECG Monitoring and Analysis
  • Synthesis and Biological Evaluation
  • HER2/EGFR in Cancer Research
  • Vascular Procedures and Complications
  • Ultrasound Imaging and Elastography
  • AI in cancer detection
  • RNA Interference and Gene Delivery
  • Thyroid Cancer Diagnosis and Treatment
  • Cancer Treatment and Pharmacology
  • Blood Coagulation and Thrombosis Mechanisms
  • Ultrasound and Hyperthermia Applications
  • Chemotherapy-induced cardiotoxicity and mitigation

Southern University of Science and Technology
2021-2025

Jinan University
2021-2023

ShenZhen People’s Hospital
2021-2022

Second Hospital of Shandong University
2021

Guangdong Medical College
2021

Marine Biomedical Research Institute of Qingdao
2021

Abstract In most solid tumors, cellular energy metabolism is primarily dominated by aerobic glycolysis, which fulfills the high demand for biomacromolecules at expense of reduced ATP production efficiency. Elucidation mechanisms rapidly proliferating malignant cells acquire sufficient in this state inefficient from glycolysis could enable development targeted therapeutic strategies. study, we observed a significant association between elevated expression levels long non-coding RNA (lncRNA)...

10.1158/0008-5472.can-24-1271 article EN Cancer Research 2025-01-22

<div>Abstract<p>In most solid tumors, cellular energy metabolism is primarily dominated by aerobic glycolysis, which fulfills the high demand for biomacromolecules at expense of reduced ATP production efficiency. Elucidation mechanisms rapidly proliferating malignant cells acquire sufficient in this state inefficient from glycolysis could enable development metabolism-targeted therapeutic strategies. In study, we observed a significant association between elevated expression...

10.1158/0008-5472.c.7719719 preprint EN 2025-03-14

A novel dual-targeted cationic microbubbles help to improve gene transfection efficiency.

10.1039/d0bm01857k article EN Biomaterials Science 2021-01-01

To explore the value of uridine diphosphate-glucuronosyltransferase 2B7 (UGT2B7)-161 single nucleotide polymorphism in predicting occurrence cardiotoxicity Chinese human epidermal growth factor 2 (HER-2) positive breast cancer patients who underwent pertuzumab combined with trastuzumab Therapy.Fifty HER-2 planned to receive and therapy for more than four cycles were enrolled this study, blood samples collected. Thirty healthy volunteers matching ages selected as control group. Myocardial...

10.2147/pgpm.s351718 article EN cc-by-nc Pharmacogenomics and Personalized Medicine 2022-03-01

Development of novel anticancer therapeutic candidates is one the key challenges in medicinal chemistry. Podophyllotoxin and its derivatives, as a potent cytotoxic agent, have been at center extensive chemical amendment pharmacological investigation. Herein, new series podophyllotoxin-N-sulfonyl amidine hybrids (4a-4v, 5a-5f) were synthesized by CuAAC/ring-opening procedure. All podophyllotoxins derivatives evaluated for vitro activity against panel human lung (A-549) cancer cell lines....

10.3390/molecules27010220 article EN cc-by Molecules 2021-12-30

To explore the application value of color Doppler ultrasonography combined with thyroid autoantibody tests in early diagnosis cancer.The medical data 100 patients nodules treated our hospital from June 2019 to 2021 were retrospectively analyzed; all received and before surgery divided into benign lesion group (n = 45) malignant 55) according postoperative pathological findings (the gold standard), so as compare analyze ultrasonography, tests, their combination cancer.Compared findings,...

10.1155/2022/5248230 article EN Computational and Mathematical Methods in Medicine 2022-04-27

Fetal heart rate (FHR) is an essential indicator of fetal well-being. The ultrasonic Doppler FHR detector widely used to monitor the fetus's health due its advantages non-invasion, high sensitivity, and good directivity. However, existing commercial primarily uses analog multiplier for demodulation, which has limited functions insufficient sensitivity. demodulation performed only on a single-sideband signal(in-phase or quadrature) (IQ), impossible derive movement's vector velocity. Moreover,...

10.1109/access.2021.3083476 article EN cc-by IEEE Access 2021-01-01

Abstract Elastography ultrasound (EUS) imaging is a vital modality. The current use of EUS faces many challenges, such as vulnerability to subjective manipulation, echo signal attenuation, and unknown risks elastic pressure in certain delicate tissues. hardware requirement also hinders the trend miniaturization equipment. We therefore present cost-efficient solution by designing deep neural network synthesize augmented reality (AR-EUS) from conventional B-mode images. By using 4580 cases 15...

10.21203/rs.3.rs-1702242/v1 preprint EN cc-by Research Square (Research Square) 2022-06-13
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