Ajwa, a variety of date palm Phoenix dactylifera L., produces the most expensive fruits. Percentages seed, moisture, fructose, glucose, soluble protein, and fiber in Ajwa dates were 13.24, 6.21, 39.06, 26.35, 1.33, 11.01, respectively. The ethyl acetate, methanolic, water extracts dates, active at 250 μg/mL MTT assay, inhibited lipid peroxidation (LPO) by 88, 70, 91% cyclooxygenase enzymes COX-1 30, 31, 32% COX-2 59, 48, 45% 100 μg/mL, Bioactivity-guided purifications afforded compounds 1-7,...

Chlorahololides A (1) and B (2), two highly complex sesquiterpenoid dimers, were isolated from Chloranthus holostegius. Their structures absolute configurations established by NMR spectroscopy, X-ray crystallography, CD. (2) exhibited potent selective inhibition on the delayed rectifier (IK) K+ current, with an IC50 of 10.9 18.6 μM, respectively.

Date fruits are reported to exhibit health-beneficial effects in addition its nutritional value. Fruits collected from commercial date palm trees were sequentially extracted with water and methanol. All varieties of contained sugars, phenolics, triterpenoids, triglycerides, fatty acids steroids, where sugars the predominant components. Water methanolic extracts assayed for antioxidant, antiinflammatory human tumor cell proliferation inhibitory activities. In MTT antioxidant assay, at 250...

Fourteen phenolic compounds, comprising four sesquilignans (1‒4), five flavonoids (5‒9), two phenylethanol glycosides (10 and 11) together with three acylphloroglucinols (12‒14), were isolated from Eucalyptus tereticornis. Their structures elucidated through spectroscopic data analyses electronic circular dichroism (ECD) calculations. Notably, tereticornisin A (1), phloretin 2¢‐O‐(6‐deoxy‐β‐D‐glucopyranoside) (6), 2¢‐O‐(6‐deoxy‐β‐D‐galactopyranoside) (7)...

Four new Daphniphyllum alkaloids, daphnilongeranins A−D (1−4), along with four known ones, daphniphylline, longistylumphylline A, deoxyisocalyciphylline B, and daphnicyclidin D, were isolated from the leaves stems of longeracemosum. Daphnilongeranin A (1) is first seco-10,17-longistylumphylline type alkaloid, daphnilongeranin B (2) a C-22 nor-Daphniphyllum alkaloid based on C21 skeleton. Their structures stereochemistry determined using spectroscopic data chemical methods.

Chuktabularins A−D (1−4), four novel 16-norphragmalin-type limonoids that feature unprecedented skeletons with a biosynthetically extended C2 or C3 unit at C-15 forming unique 2,7-dioxabicyclo[2.2.1]heptane moiety, were isolated from the stem bark of Chukrasia tabularis. Their structures elucidated by spectroscopic analysis and computer modeling. The biosynthetic pathway 1−4 was postulated.

Two novel limonoids, chuktabrin A (1), featuring the unique motifs of a 1,3-dioxolan-2-one and 3,4-dihydro-2 H-pyran, B (2), possessing an unprecedented polycyclic skeleton, were isolated from Chukrasia tabularis. The structures 1 2 bearing biosynthetically extended C3 C2 unit at C-15, respectively, elucidated on basis spectroscopic data, that was confirmed by single-crystal X-ray diffraction.

A rare class of onoceranoid-type triterpenoids, represented by lamesticumin (1), the ethanolysis product (2), lamesticumins B−F (3−7), lansic acid 3-ethyl ester (8), and ethyl lansiolate (9), along with four known analogues were isolated from twigs Lansium domesticum. Their structures elucidated on basis extensive spectroscopic analysis, absolute configuration C-21 in compound 7 was assigned using Snatzke's method. Compounds 1−9 exhibited moderate antibacterial activity against Gram-positive...

Biogenesis inspired chemical investigation of a Chinese folk medicine, Flueggea virosa, returned three unprecedented C,C-linked trimeric Securinega alkaloids, fluevirosines A–C (1–3). Their absolute structures were characterized on the basis spectroscopic data and computational analysis. Compounds 2 3 showed inhibition against splicing XBP1 mRNA.

Three new norlimonoids, toonaciliatins A (1), F (6), and G (7), four limonoids, B−E (2−5), five known compounds, 5α,6β,8α-trihydroxy-28-norisotoonafolin (8), H (9) I (10), febrifugin (11), khayasin T (12), were isolated from the leaves stems of Toona ciliata. Compounds 1−3 have an unusual 1-en-3-one system with a 1,11-oxygen bridge, limonoids 11 12 mexicanolide-type structural frame, others are typical A,B-seco- (4, 5, 9, 10) or B-seco-29-nor- (3, 6, 7, 8) limonoids. Toonaciliatins (10)...

Seven new sesquiterpenoids, chlorantenes A−G (1−7), two phenylpropanoids (8 and 9), six known sesquiterpenoids were isolated from the whole plants of Chloranthus serratus. Their structures elucidated on basis spectroscopic analyses. Chlorantene A (1) was a sesquiterpene with unique C-4 C-10 linkage, chlorantene B (2) possessed nitro group at C-1. The structure eudesmane-type previously henryi revised as its 4-epimer (3a).

Twelve new alkaloids, caldaphnidines G−R (1−12), along with 24 known ones, were isolated from the twigs of Daphniphyllum calycinum. Their structures elucidated by spectroscopic methods, especially two-dimensional NMR techniques.

Five new limonoids, tabularisins E–I (1–5), and a dinorcycloartane, (24R)-28,29-dinor-cycloartane-3β,24,25-triol (6), together with three known compounds, were isolated from the twigs leaves of Chukrasia tabularis var. velutina. Their structures elucidated primarily on basis spectroscopic methods.

Eleven new mexicanolide-type limonoids, swietmanins A−I (1−4, 7−11), 2-hydroxy-3-O-isobutyrylproceranolide (5), 2-hydroxy-3-O-benzoylproceranolide (6), and a andirobin-type limonoid, swietmanin J (12), together with 19 known compounds were isolated from the fruits of Swietenia mahagoni. Their structures established on basis spectroscopic methods. These evaluated against small panel microorganisms.

Three limonoids (1-3), and two triterpenes (4) (5), along with twelve known compounds, were isolated from the seeds of Melia azedarach. Their structures established on basis extensive spectroscopic analysis. Compound 3 showed moderate antimicrobial activity.

Nine new daphnane-type diterpenoids (1–9), named trigohownins A–I, and four known analogues were isolated from Trigonostemon howii. Their structures elucidated on the basis of extensive NMR MS analyses. Trigohownins A (1) D (4) exhibited moderate cytotoxic activity against HL-60 tumor cell line, with IC50 values 17.0 9.3 μM, respectively.

Three new sesquiterpenes (1-3), (6R,7S,11R,10S)-15-hydroxy-sesquisabinene hydrate (1), (6R,7R,11S,10S)-15-hydroxy-sesquisabinene (2), and (6R,7R,10S)-15-hydroxy-zingiberenol (3), along with three known compounds, were isolated from the stems of Dysoxylum oliganthum; isodaucane (salvionane) sesquiterpenes, namely isodauc-6-ene-10β,14-diol (4), 4-epi-isodauc-6-ene-10β,14-diol (5), 4-epi-6α,10β-dihydroxy-artabotrol (6) together 15 compounds twigs leaves D. excelsum. Their structures established...

A series of <italic>Securinega</italic> alkaloid hybrids and oligomers with anti-HIV activity were isolated identified from <italic>Flueggea virosa</italic>.

A new highly oxygenated sterol, 22E, 24R-ergosta-7,22-diene-3β,5α,6β,9α,14α-pentol (1), as well four known sterols (2–5) and seven triterpenoids, have been isolated from the spores of Ganoderma lucidum. The structure compound 1 was elucidated on basis spectroscopic method.

Ten new limonoids, namely, mesendanins A−J (1−10), together with 14 known compounds, have been isolated from the leaves and twigs of Melia toosendan. Their structures were established on basis spectroscopic data analysis.

Seven new limonoids (1-7), named khayalenoids C-I, three triterpenoids (8-10), senegalenes A-C, and eight known have been isolated from stems of Khaya senegalensis. The structures these compounds were elucidated on the basis spectroscopic analyses.