The reliable characterization of insulation materials in relevant environmental conditions is crucial, since it strongly influences the performance (e.g., thermal) building elements. In fact, their properties may vary with moisture content, temperature, ageing degradation, etc. Therefore, this work, thermomechanical behaviour different was compared when subjected to accelerated ageing. Insulation that use recycled rubber composition were studied, along others for comparison: heat-pressed...

An in situ evaluation of the dsDNA–methotrexate (MTX) interaction was performed by voltammetry using a DNA-electrochemical biosensor and characterized atomic force microscopy (AFM) at highly oriented pyrolytic graphite (HOPG) surface. Electrochemical experiments incubated solutions showed that MTX with dsDNA leads to modifications structure time-dependent manner. The AFM images show reorganization DNA self-assembled network on surface HOPG electrode upon binding methotrexate formation more...

The transition from fossil fuels is in part limited by our inability to store energy at different scales. Batteries are therefore high demand, and we need them more energy, be reliable, durable have less social environmental impact. Silica-poly(vinyl alcohol) (PVA) composite aerogels doped with sodium perchlorate were synthesized as novel electrolytes for potential application solid-state batteries. aerogels, one-pot synthesis, light (up 214 kg m−3), porous (~85%), exhibit reduced shrinkage...

Abstract The electrochemical redox behavior of omeprazole (OMZ), a gastric acid pump inhibitor, was investigated at glassy carbon electrode using cyclic, differential pulse and square‐wave voltammetry over wide pH range. pH‐dependent oxidation occurs in two irreversible consecutive charge transfer reactions. Adsorption the nonelectroactive product also observed. first involves removal one electron, followed by deprotonation leads to formation hydroxylated species. second process is related...

The Tetrahymena telomeric repeat sequence d(TG4T) contains only guanine (G) and thymine (T) bases has medical nanotechnological applications because of its ability to self-assemble into stiff tetra-molecular parallel-stranded G-quadruplexes. hexadeoxynucleotide was studied using atomic force microscopy (AFM) on the highly oriented pyrolytic graphite surface differential pulse (DP) voltammetry at a glassy carbon electrode. single-strands self-assembled G-quadruplex structures, very fast in K+...

Silica aerogel is a material composed of SiO2 that has exceptional physical properties when utilized for tissue engineering applications. Poly-ε-caprolactone (PCL) biodegradable polyester been widely used biomedical applications, namely as sutures, drug carriers, and implantable scaffolds. Herein, hybrid composite silica aerogel, prepared with two different precursors, tetraethoxysilane (TEOS) or methyltrimethoxysilane (MTMS), PCL was synthesized to fulfil bone regeneration requirements. The...

Abstract Methotrexate (MTX) is an antimetabolite of folic acid indicated in the treatment a variety cancers. The electrochemical behaviour MTX on glassy carbon electrode was investigated. oxidation complex, pH‐dependent, diffusion‐controlled irreversible process and proceeds with transfer two electrons protons formation one electroactive product, 7‐hydroxymethotrexate that undergoes reversible redox reaction. reduction quasi‐reversible involves leading to product.

Silica aerogel composites with recycled tire rubber have been synthesized and evaluated for their potential use thermal protection in buildings. The present work describes the first time preparation of silica-based containing tires reinforced polyvinyl butyral (PVB) by hot pressing. developed composite was extensively characterized regarding its physical, morphological, mechanical features, results showed properties were relevant, leading to different properties/performances. obtained bulk...

Hydrophobic rubber-silica aerogel panels (21.5 × 21.5 1.6 cm3) were fabricated from silica and rubber sols reinforced with several fiber types (recycled tire textile fibers, polyester blanket, felt, glass wool). A recycled sol was prepared using peracetic acid incorporated for the first time in TEOS-based sol-gel chemistry. The composites exhibited good thermal stability up to 400 °C very low conductivity, superinsulation range when fibers (16.4 ± 1.0 mW·m−1·K−1), of 20–30 mW·m−1·K−1...

The interactions of the Tetrahymena telomeric repeat sequence d(TG4T) and polyguanylic acid (poly(G)) with quadruplex-targeting triazole-linked acridine ligand GL15 were investigated using atomic force microscopy (AFM) at a highly oriented pyrolytic graphite voltammetry glassy carbon electrode. interacted both sequences, in time dependent manner, G-quadruplex formation was detected. AFM showed adsorption quadruplexes as small poly(G) spherical aggregates large quadruplex-based assemblies,...

Abstract Metolazone is a diuretic agent used in patients with edematous states and/or hypertension. The electrochemical behavior of metolazone on glassy carbon electrode was investigated using cyclic, differential pulse, and square‐wave voltammetry at different pHs. pH dependent oxidation occurs two consecutive steps diffusion‐controlled mechanism involves the formation main product. first process reversible, electrons protons corresponding to nitrogen sulfonamide moiety. second...

Abstract Cladribine (CLD), 2‐chlorodeoxyadenosine, was investigated at a glassy carbon electrode using cyclic, differential pulse and square wave voltammetry over wide pH range. The oxidation of CLD is an irreversible, pH‐dependent with the transfer two electrons protons mechanism, leading to formation hydroxylated species which undergoes reversible redox reactions one electron proton. in situ evaluation DNA‐CLD interaction DNA‐electrochemical biosensor investigated. causes dsDNA structural...

Abstract In this work, the electrochemical behavior of flavonolignan silybin (SB) and 2,3‐dehydrosilybin (DHSB) their respective conjugates SB‐SB DHSB‐DHSB were studied using voltammetric techniques at a glassy carbon electrode. The redox mechanism SB its conjugate occurs in two oxidation steps where hydroxy groups guaiacyl resorcinol moiety are involved. DHSB oxidized three subsequent steps. enol group is involved additional step, due to enhanced electron‐donor capacity reactivity...

The electrochemical redox behavior of usnic acid, mainly known for its antibiotic activity, has been investigated using cyclic, differential pulse and square wave voltammetry in aqueous electrolyte. These studies were carried out by solid state with the mechanically attached on surface a glassy carbon electrode at different pH values. Usnic acid did not present any reduction reaction. pH-dependent oxidation occurs three steps, one electron proton irreversible processes, assigned to each...

Abstract The planning, implementation and results of the first edition Molecular School are presented, as pre-university school project held in Portugal. This is not, however, a strictly Portuguese project, since it can be replicated other countries at secondary level, with minor adjustments. Herein, pilot detailed discussed, where 36 students have participated. plan for second edition, to semester 2021, confirmed participation around 100 students, further presented. Briefly, divided two...