A5082550113- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Photochromic and Fluorescence Chemistry
- Photochemistry and Electron Transfer Studies
- Synthesis and biological activity
- Synthesis and Properties of Aromatic Compounds
- Luminescence and Fluorescent Materials
- Molecular Sensors and Ion Detection
- Synthesis and Characterization of Heterocyclic Compounds
- Metal complexes synthesis and properties
- biodegradable polymer synthesis and properties
- Porphyrin and Phthalocyanine Chemistry
- Electrochemical sensors and biosensors
- Fermentation and Sensory Analysis
- Advanced NMR Techniques and Applications
- Advanced biosensing and bioanalysis techniques
- Synthesis and Biological Evaluation
- Electron Spin Resonance Studies
- Electrochemical Analysis and Applications
- Click Chemistry and Applications
- Analytical Chemistry and Sensors
- Lanthanide and Transition Metal Complexes
- Chemical Synthesis and Analysis
- Synthesis of Organic Compounds
- Fluorine in Organic Chemistry
Romanian Academy
2016-2025
University of Bucharest
2016-2025
Institute of Organic Chemistry
2014-2024
Institute of Catalysis and Petrochemistry
2019
Universitatea Națională de Știință și Tehnologie Politehnica București
2011-2018
Centre for Organic Chemistry (Czechia)
2018
George Enescu University of Arts of Iași
2012
The saponification value of fats and oils is one the most common quality indices, reflecting mean molecular weight constituting triacylglycerols. Proton nuclear magnetic resonance (1H-NMR) spectra display specific resonances for protons from structural patterns triacylglycerols (i.e., glycerol backbone), methylene (-CH2-) groups, double bonds (-CH=CH-) terminal methyl (-CH3) group three fatty acyl chains. Consequently, chemometric equations based on integral values 1H-NMR allow calculation...
Herein, we present an efficient approach for developing electrochemical aptasensing interfaces, by "click" postfunctionalization of phenylethynyl-grafted glassy carbon substrates with mixed monolayers containing biorecognition elements and phosphorylcholine zwitterionic groups. Typically, controlling the composition multicomponent surface layers grafting from a mixture aryldiazonium salts is challenging due to differences in their chemical reactivity. Our circumvents this issue employing...
Three complexes of Cd(II), [Cd(NA)₂(NO₃)₂(H₂O)₂] (1), [Cd(NA)₂(NO₃)₂(H₂O)₂]·2NA (2), and [Cd(ox)(NA)(H₂O)]·H₂O (3) (NA = nicotinamide, ox oxalate) were synthesized characterized. Complexes (1) (2) are mononuclear, while complex is a bidimensional polymeric coordination compound, with oxalate anions bridging metal ions in two different ways: µ₂ bis-bidentate chelating manner µ₄ bis-monodentate manner. The stereochemistry Cd(II) compounds distorted pentagonal bipyramid, compound it regular...
We present herein synthesis of novel [2+2] and [3+3] N-acylhydrazone-based macrocycles using a pool dialdehydes dihydrazides, under thermodynamic control. The resulted macrocycles, which were assigned triangular rectangular...
Background/Objectives: The deterioration of food quality and safety is often linked to the presence pathogenic spoilage microorganisms. Postbiotics, including organic acids, enzymes, bacteriocins produced by lactic acid bacteria (LAB), have emerged as promising next-generation preservatives. This study investigates biological physicochemical properties several postbiotic-based extracts (PBEs) comprising cell-free supernatant (CFS) exopolysaccharide (EPS) fractions derived from three native...
In this paper we report the functionalization of conductive polypyrrole (PPY) films via electrochemical reduction aryl diazonium salts in a manner that is similar to one employed for other surfaces. To understand general trends grafting behavior and establish optimal conditions covalent PPY films, have compared four p-substituted phenyldiazonium salts: p-nitrophenyl tetrafluoroborate (PNBDBF4−), p-tolyl (TDBF4−), p-fluorophenyl (FPDBF4−) 4-diazo-N,N-dimethylaniline (DDMABF4−). The selection...
Several photo‐curable hybrid systems based on methacrylate‐modified camelina oil (CO) were synthesized through a copolymerization reaction with hydrophilic dimethacrylated poly(ethylene glycol) macromonomers (PEG MW = 300, 550, and 750 g/mol). In first step, the epoxidation subsequently methacrylation reactions of CO performed monitorized using 1 H NMR FTIR. Further, polymerization new oil‐based monomer under visible light was proved by The chain length methacrylate functionalized PEG found...
Abstract Triglyceride‐based monomers represent a competitive alternative to petrochemical resources in the macromolecular compounds area. In current study, several types of hydrophilic camelina oil (CO)‐based were synthesized using tunable experimental protocols that involve three different steps: first—conversion double bonds into epoxy rings, second—partial opening rings and methacrylic groups grafting last—opening unreacted units attaching. 1H‐NMR, 13C‐NMR FTIR spectroscopy demonstrate...
This paper investigated the limits of current approach for determination fatty acids profile milk fats from proton nuclear magnetic resonance data based on hypothesis that signal at 0.96 ppm, currently assigned in literature as a marker "short chain acids," is generated only by butyric moiety (not all short-chain acids, which also include C6:0—caproic acid). The was tested and experimentally confirmed. Moreover, triplet ppm can be due to n-3 such linolenic acid (C18:3); therefore, previously...
Thiadiazole derivatives have garnered significant attention in the field of medicinal chemistry due to their diverse pharmacological activities, including anticancer properties. This article presents synthesis a series thiadiazole and investigates chemical characterization potential effects on various cell lines. The results nuclear magnetic resonance (NMR) analyses confirmed successful formation target compounds. was evaluated through silico vitro cell-based assays using LoVo MCF-7 cancer...
Poly(propylene fumarate) (PPF) is a linear unsaturated polyester which has been widely investigated for tissue engineering due to its good biocompatibility and biodegradability. In order extend the range of possible applications enhance mechanical properties, current approaches consist in incorporation various fillers or obtaining blends with other polymers. study we designed reinforcing agent based on carboxylated graphene oxide (GO-COOH) grafted 2-hydroxyethyl methacrylate (GO@HEMA)...
Starting from isoniazid and carboxylic acids as precursors, thirteen new hydrazides 1,3,4-oxadiazoles of 2-(4-substituted-phenoxymethyl)-benzoic were synthesized characterized by appropriate means. Their biological properties evaluated in terms apoptosis, cell cycle blocking, drug metabolism gene expression on HCT-8 HT-29 lines. In vitro antimicrobial tests performed the microplate Alamar Blue assay for anti-mycobacterial activities an adapted agar disk diffusion technique other...
Abstract Benzoxazine derivatives were synthesized using phenolated methyl oleate and either aniline, 1,6‐diaminohexane, or 4,4′‐diaminodiphenylmethane, respectively, as amine components. Polymerization of the benzoxazine led to formation hydrophobic dense coatings on Zn‐Mg‐Al alloy coated steel sheets for passive corrosion protection. The polybenzoxazine which are formed by crosslinking during a heat‐treatment step invoked substantial anodic shift open‐circuit potential well breakthrough in...
New 1′-homocarbanucleoside analogs with an optically active substituted bicyclo[2.2.1]heptane skeleton as sugar moiety were synthesized. The pyrimidine uracil, 5-fluorouracil, thymine and cytosine key intermediate 6-chloropurine (5) nucleobases synthesized by a selective Mitsunobu reaction on the primary hydroxymethyl group in presence of 5-endo-hydroxyl group. Adenine 6-substituted adenine homonucleosides obtained substitution 6-chlorine atom 5 ammonia selected amines, 6-methoxy- 6-ethoxy...