- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Probiotics and Fermented Foods
- Meat and Animal Product Quality
- Digestive system and related health
- Phytochemistry and Biological Activities
- Advanced Chemical Sensor Technologies
- Free Radicals and Antioxidants
- Seaweed-derived Bioactive Compounds
- Berberine and alkaloids research
- Ethnobotanical and Medicinal Plants Studies
- Computational Drug Discovery Methods
- Food Industry and Aquatic Biology
- Microencapsulation and Drying Processes
- Natural Antidiabetic Agents Studies
- Phytochemical and Pharmacological Studies
- Bee Products Chemical Analysis
- Nutrition, Genetics, and Disease
- Sensory Analysis and Statistical Methods
- Diagnosis and Treatment of Venous Diseases
- Pomegranate: compositions and health benefits
- Proteins in Food Systems
- Seed and Plant Biochemistry
- Cynara cardunculus studies
- Dye analysis and toxicity
Technical University of Moldova
2019-2024
Carol Davila University of Medicine and Pharmacy
2023-2024
ORCID
2019
The saponification value of fats and oils is one the most common quality indices, reflecting mean molecular weight constituting triacylglycerols. Proton nuclear magnetic resonance (1H-NMR) spectra display specific resonances for protons from structural patterns triacylglycerols (i.e., glycerol backbone), methylene (-CH2-) groups, double bonds (-CH=CH-) terminal methyl (-CH3) group three fatty acyl chains. Consequently, chemometric equations based on integral values 1H-NMR allow calculation...
Capsicum annuum (L.) is one of the essential spices most frequently used in our daily routine and has remarkable ethnobotanical pharmacological properties. Its fruits are rich vitamins, minerals, carotenoids, numerous other phenolic metabolites with a well-known antioxidant activity. Regular consumption chili may have positive influence on human health. Therefore, we investigated commercially available fruit powder present study, extracting it 50% ethanol. The dried hydro-ethanolic extract...
This study focused on the development of a yogurt with an improved structure, texture and antioxidant activity level, by using apple pomace (AP) powder that was obtained in large quantities during production juices. The objective to determine sensory, physicochemical, textural characteristics addition AP (0.2-1.0%), its shelf life. physicochemical composition determined as follows: dietary fibers-62.73%, including pectin-23.12%; content compounds AP-total polyphenols (728.8 mg GAE/100 g DW),...
Lipid metabolism dysregulation can lead to dyslipidemia and obesity, which are major causes of cardiovascular disease associated mortality worldwide. The purpose the study was obtain characterize six plant extracts (ACE-
The aim of this study was to investigate the effects dry-aging method on sensory properties, chemical composition, and profile parameters texture beef obtained from local farms. qualitative characteristics were investigated for five samples, respectively, fresh meat, dry-aged 14, 21, 28, 35 days, in aging rooms with controlled parameters: temperature (1 ± 1 °C), relative humidity (80 5%), air circulation speed (0.5-2 m/s). During period, there a decrease by about 6.5% first 21 which allowed...
The present study focuses on the chemical characterization of a dry extract obtained from species Ajuga chamaepitys (L.) Schreb, evaluating its antioxidant properties, toxicity, and in silico profile. Quantitative analysis revealed notable amount phytochemical compounds: 59.932 ± 21.167 mg rutin equivalents (mg REs)/g weight, 45.864 4.434 chlorogenic acid ChAEs)/g weight and, respectively, 83.307 3.989 tannic (TAEs)/g weight. By UHPLC-HRMS/MS, following were quantified as major caffeic...
Oxidative stress is the most critical factor in multiple functional disorders' development, and natural antioxidants could protect human body against it. Our study aims to investigate polyphenol content of four extracts two medicinal plants (Rosmarinus officinalis L. Thymus vulgaris L.) analyze correlation with their antioxidant activity. The research was carried out on rosemary thyme obtained from species cultivated together plant communities. Both were compared individual crops (control...
The problem of food with functional ingredients, characterized by low energy intake and a variety phytonutrients biological activity, is one the concerns population. objectives this study were to investigate effect pumpkin powder its bioactive components on quality, color textural properties shortbread cookies. In drying process (Cucurbita moschata) at 60 ± 2 °C, physicochemical parameters did not change significantly in relation fresh pulp. chromatic L*, a* b* showed that was brighter than...
The article investigated the antioxidant and antimicrobial activity of extracts from two aromatic plants-Satureja hortensis L. (SE) Rosmarinus officinalis (RE), encapsulated in alginate, on-yogurt properties. encapsulation efficiency was controlled by FTIR SEM analysis. In both extracts, individual polyphenol content determined HPLC-DAD-ESI-MS. total were spectrophotometrically quantified. properties SE RE against gram-positive bacteria (Bacillus cereus, Enterococcus faecalis, Staphylococcus...
Endothelial dysfunction is the basis of physiopathological mechanisms vascular diseases. In addition to therapeutic activity plant extracts, cytotoxicity significant. This research evaluates three vegetal extracts (Calendulae flos extract-CE, Ginkgo bilobae folium extract-GE, and Sophorae extract-SE). vitro evaluation was performed using an endothelial cell line model (Human Pulmonary Artery Cells—HPAEC) when a dose-dependent cytotoxic observed after 72 h. The IC50 values were calculated for...
Berberis vulgaris (L.) has remarkable ethnopharmacological properties and is widely used in traditional medicine. The present study investigates B. stem bark (Berberidis cortex) by extraction with 50% ethanol. main secondary metabolites were quantified, resulting a polyphenols content of 17.6780 ± 3.9320 mg Eq Tannic acid / 100 g extract, phenolic acids amount 3.3886 0.3481 Chlorogenic extract 78.95 µg/g berberine. dried hydro-ethanolic (BVE) was thoroughly analyzed using Ultra-High...
Nanotechnology is one of the newest directions for plant-based therapies. Chronic venous disease often predisposes to long-term and invasive treatment. This research focused on inclusion vegetal extracts from Sophorae flos (SE), Calendulae (CE), Ginkgo bilobae folium (GE) in formulations with PHB PLGA polymers their physicochemical characterization as a preliminary stage possible use development complex therapeutic product. The samples were prepared by an oil–water emulsification solvent...
Xerosis cutis represents one of the most common dermatological diagnoses, which, when untreated, can be trigger for open wounds, infections, and other skin diseases. Plant extracts are a valuable option long-term treatments xerosis due to their phytocompounds, especially polyphenols, flavonoids, triterpenes, polysaccharides, with antioxidant, anti-inflammatory, antimicrobial, moisturizing, reparatory effects. Active substances have different mechanisms; therefore, evaluating effects on cells...
The purpose of the work was to investigate influence different lactose hydrolysis processes, contribution enzyme and milk type on characteristics obtained lactose-free yogurt. analysis performed non-hydrolyzed yogurt (control sample), pre-hydrolyzed (that hydrolyzed before fermentation), co-hydrolyzed (concurrent addition β-galactosidase starter culture). According results, at end fermentation time, an advanced degree reached (over 80%) both for samples from by co-hydrolysis. optimal method...
This article aimed to review the recent literature on characterization of dietary fibers and their role in human body, focusing methods extraction from agro-food waste as well use various areas food industry. Dietary are biologically active substances with beneficial effects health. Soluble fiber is involved reducing cholesterol levels blood sugar levels, while insoluble helps regulate intestinal transit maintain colon It would be useful identify procedures waste. Fruit contains relevant...
Lactose intolerance is becoming a health state that requires the restriction of dairy products in diet people suffering from this condition. But milk and products, due to well-balanced composition main macro micronutrients, cannot be missing consumer any age. For these reasons, recent years, processing industry, production low-lactose or lactose-free explored. To reduce lactose content raw materials, various industrial biotechnological methods were used: enzymatic hydrolysis lactose,...
The antimicrobial and antioxidant effects of plant extracts are well known, but their use is limited because they affect the physicochemical sensory characteristics products. Encapsulation presents an option to limit or prevent these changes. paper composition individual polyphenols (HPLC-DAD-ESI-MS) from basil (Ocimum basilicum L.) (BE), activity inhibitory against strains Staphylococcus aureus, Geobacillus stearothermophilus, Bacillus cereus, Candida albicans, Enterococcus faecalis,...
Berberis vulgaris (L.) has remarkable ethnopharmacological properties and is widely used in traditional medicine. The present study investigated B. stem bark (Berberidis cortex) by extraction with 50% ethanol. main secondary metabolites were quantified, resulting a polyphenols content of 17.6780 ± 3.9320 mg Eq tannic acid/100 g extract, phenolic acids amount 3.3886 0.3481 chlorogenic extract 78.95 µg/g berberine. dried hydro-ethanolic (BVE) was thoroughly analyzed using...
The purpose of this study was to first evaluate the antimicrobial effects powder and extracts berries (rose-hip, aronia, sea buckthorn hawthorn) on development antibiotic-resistant L. monocitogenes. Listeria monocytogenes is considered one most important pathogens responsible for food-borne infection. Antimicrobial properties were evaluated using standard Kirby-Bauer disk diffusion method. Bacterial inactivation networks determined compared, as well possibility powders control risk...
The article elucidates the possibility of using yellow dye, obtained from saffron petals (Carthamus Tinctorius L.) in food industry. This powdered added to yoghurt concentrations 0.3 – 0.4%, addition its color, gives samples a light aroma flowers and demonstrates high stability during storage at 4° C. for 28 days. values chromatic coordinates, L *, b yogurt did not undergo considerable changes stage, color difference ΔE being ≤ 0.79, which indicates dye yogurt. samples. analysis data...
Dairy products are susceptible to contamination by foodborne pathogenic and spoilage microorganisms, which can result a reduced shelf life of as well risks the consumers’health. This determines possible use preservatives in manufacturing process dairy products. Consumers require healthy food, free synthetic preservatives, looking for natural alternatives ensure food safety. Just this reason, ingredients receiving increasing attention substitutes additives. Currently, research is focusing on...
The paper is a review of the importance expanding lactose-free dairy segment to give consumers opportunity consume milk and products if they suffer from lactose intolerance. When there lactase deficiency in body, small intestine not hydrolyzed, volume increases fluidity intestinal contents increases, allowing reach colon where it fermented by colonic bacteria. Lactose intolerance condition that depending on form developed will show different symptoms suffering this disease may ingest amounts...
Research work involves the instrumental analysis of change in color (L*, a*, b*) and sensory characteristics Simmental beef, parts carcass: T-bons, received from local farm, during dry-aging period for 0, 14, 21, 28, 35 days roasted aged beef at high very temperatures. The analyzed samples presented uniform results chromatic parameters period, being influenced by values meat pH water-holding capacity, namely: dry-aged meat, L* parameter indicate an increase brightness a* parameter,...