A5086559364- Carbohydrate Chemistry and Synthesis
- Genomics, phytochemicals, and oxidative stress
- Sulfur-Based Synthesis Techniques
- Chemical Synthesis and Reactions
- Synthesis and Catalytic Reactions
- Synthesis of heterocyclic compounds
- Free Radicals and Antioxidants
- Chemical Synthesis and Analysis
- Molecular spectroscopy and chirality
- Catalytic C–H Functionalization Methods
- Synthesis and biological activity
- Glycosylation and Glycoproteins Research
- Organic and Inorganic Chemical Reactions
- Carbon dioxide utilization in catalysis
- Moringa oleifera research and applications
- Synthetic Organic Chemistry Methods
- Phytochemicals and Antioxidant Activities
- Polyamine Metabolism and Applications
- Diet, Metabolism, and Disease
- Analytical Chemistry and Chromatography
- Click Chemistry and Applications
- Asymmetric Synthesis and Catalysis
- Biochemical Acid Research Studies
- Biochemical and Molecular Research
- Synthesis of Organic Compounds
Université d'Orléans
2014-2024
Centre National de la Recherche Scientifique
2013-2024
Institut de Chimie Organique et Analytique
2014-2023
University of Lisbon
2008
University of Messina
2002-2005
Research Centre for Cereal and Industrial Crops
2005
University of Bologna
2005
University of Bath
2000-2002
Université Joseph Fourier
1995-1999
Université Grenoble Alpes
1996-1997
The most promising among glucosinolates (GLs) are those bearing in their aglycon an extra sulfur function, such as glucoraphasatin (4-methylthio-3-butenyl GL; GRH) and glucoraphenin (4-methylsulfinyl-3-butenyl GRE). GRE/GRH redox couple is typically met secondary metabolites of Raphanus sativus L. and, whereas GRE prevails seeds, GRH the major GL full-grown roots. During 10 days sprouting R. contents were determined according to Eurpean Union official method (ISO 9167-1). In comparison...
A. Tatibouët, M. Demeunynck, C. Andraud, Collet and J. Lhomme, Chem. Commun., 1999, 161 DOI: 10.1039/A808822E
Cyclic thionocarbamates, namely chiral oxazolidinethiones (OZT) and aromatic oxazolinethiones (OXT), were involved, for the first time, in Sonogashira cross-coupling. A cooperative effect of two different copper (I) speciesCuI CuTCaccounts this new copper-catalyzed desulfurative carbon−carbon cross-coupling reaction. This reactivity could also be extended to other catalysts.
The GLUT5 transporter catalyses the specific uptake of D-fructose and can accept this hexose in its furanose pyranose ring forms. does not fructose epimers has very limited tolerance bulky groups substituted at 2-, 3-, 4- 5-OH positions [Tatibouët, Yang, Morin Holman (2000) Bioorg. Med. Chem. 8, 1825-1833]. To further explore whether be tolerated primary OH positions, a analogue with an allylamine group substitution to replace 1-OH was synthesized found quite well ( K (i)=27.1 mM). However,...
Activated 1,2-glycerol carbonate has been subjected to nucleophilic substitution with oxygen-, nitrogen- and sulfur nucleophiles. Selective reactions thiol derivatives have especially investigated for the preparation of mono- dithiofunctionalized 3-carbon synthons. Keywords: Glycerol carbonate, renewable resources, thiofunctionalization, oxidation
Starting from isoniazid and carboxylic acids as precursors, thirteen new hydrazides 1,3,4-oxadiazoles of 2-(4-substituted-phenoxymethyl)-benzoic were synthesized characterized by appropriate means. Their biological properties evaluated in terms apoptosis, cell cycle blocking, drug metabolism gene expression on HCT-8 HT-29 lines. In vitro antimicrobial tests performed the microplate Alamar Blue assay for anti-mycobacterial activities an adapted agar disk diffusion technique other...
Both anomers of O-protected 1-thio-d-gluco- and -d-mannopyranoses were selected to provide the substrates for developing a smooth general methodology that gives access anomeric glycosulfoxides. The behavior corresponding β-d-galactopyran derivatives was also investigated. 2-{1-[(2,3,4,6-Tetra-O-acetyl-β-d-glucopyranosyl)sulfinyl](1-methyl)ethyl}malonic acid diethyl esters 4 thermolyzed in refluxing dichloromethane generating 2,3,4,6-tetra-O-acetyl-β-d-glucopyranose-1-sulfenic (8), presence...
Abstract First to fifth generations of poly(propyleneimines) (PPIs) were reacted with glycerol carbonate yielding a new family glycerol‐decorated PPIs (GD‐PPI). Owing the presence glyceryl units surrounding PPI core, high generation GD‐PPI‐5 can be successfully immobilized in phase, thus offering convenient route for possible utilization as recyclable homogeneous catalyst. In this context, we show here that used basic catalyst ring opening epoxides carboxylic acids glycerol. The affinity...
Pentadiplandra brazzeana Baillon (Pentadiplandraceae) is known to contain benzyl-, 3-methoxybenzyl-, 4-methoxybenzyl-, 3,4-dimethoxybenzyl-, and indole-type glucosinolates, the essential oil obtained from its roots mainly constituted of benzyl isothiocyanate cyanide. In a previous study by authors, it was surmised that partial hydrolytic degradation 4-methoxybenzyl isothiocyanate, one major expected compound, occurred during hydrodistillation process preparation. To probe this hypothesis,...
Myrosinase, a thioglucoside glucohydrolase, is the only enzyme able to hydrolyse glucosinolates, unique family of molecules bearing an anomeric O-sulfated thiohydroximate function. Non-hydrolysable myrosinase inhibitors have been devised and studied for their biological interaction. Diverse modifications O-sulfate moiety did not result in significant inhibitory effect, whereas replacing D-glucopyrano residue by its carba-analogue allowed inhibition take place. X-Ray experiments carried out...
Abstract A new method for accessing the thiohydroximate function allows an alternative synthetic pathway to glucosinolates. O ‐Silylated hydroxamic acids were prepared and then activated with triflic anhydride generate transient nitrile oxides be condensed ethanethiol. The procedure was further applied synthesis of naturally occurring
The asymmetric synthesis of endocyclic methionine sulfilimines and sulfoximines from derivatives was explored. cyclization performed by using phenyliodine diacetate (PIDA). In the case l-methionine, dehydromethionine obtained, a deprotonation step tBuONa necessary to yield corresponding sulfilimine. On other hand, cyclic sulfilimine methyl ester, methylthiopropylamine, l-methioninol were synthesized in single PIDA. Owing their instability, oxidized good yields.