A5100674762- Nanomaterials for catalytic reactions
- Aerospace Engineering and Energy Systems
- Oxidative Organic Chemistry Reactions
- Crystallization and Solubility Studies
- Chemical Synthesis and Analysis
- Catalytic C–H Functionalization Methods
- Asymmetric Hydrogenation and Catalysis
- Spacecraft and Cryogenic Technologies
- Advanced ceramic materials synthesis
- Graphite, nuclear technology, radiation studies
- Conducting polymers and applications
- X-ray Diffraction in Crystallography
- Nuclear and radioactivity studies
- Fibroblast Growth Factor Research
- Petroleum Processing and Analysis
- Advanced biosensing and bioanalysis techniques
- DNA and Nucleic Acid Chemistry
- Metal complexes synthesis and properties
- Microwave-Assisted Synthesis and Applications
- Spacecraft Dynamics and Control
- Magnetism in coordination complexes
- Lanthanide and Transition Metal Complexes
- Graphene research and applications
- Advanced Photocatalysis Techniques
- Eosinophilic Disorders and Syndromes
Hunan University of Technology
2018-2025
University of Strathclyde
2024
Jiangxi Normal University
2023
Central South University
2009-2022
Xiangya Hospital Central South University
2017-2022
China University of Petroleum, East China
2019
Tsinghua University
2018
Hangzhou Medical College
2017
Hunan Cancer Hospital
2016
China Energy Engineering Corporation (China)
2016
Polyacrylic acid (PAA) as a binder in the aqueous solvent is applied preparation of sulfur cathode for lithium-sulfur battery. Electrochemical performances are investigated by charge-discharge cycle test, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). CV EIS tests indicate that PAA has smaller resistance better kinetics characteristics than poly(vinylidene fluoride) (PVDF) using PVDF N-methy-2-pyrrolidone (NMP) solvent. The show discharge capacity coulombic...
FOXA2, a member of the forkhead family transcription factors, plays essential roles in liver development and bile acid homeostasis. In this study, we report 2.8 Å co-crystal structure FOXA2 DNA-binding domain (FOXA2-DBD) bound to DNA duplex containing consensus binding site (GTAAACA). The FOXA2-DBD adopts canonical winged-helix fold, with helix H3 wing 1 regions mainly mediating recognition. Although 2 region was not defined structure, isothermal titration calorimetry assays suggested that...
Aberrant FGFR4 signaling has been documented abundantly in various human cancers. The majority of FGFR inhibitors display significantly reduced potency toward compared to FGFR1-3. However, LY2874455 similar inhibition for FGFR1-4 with IC50 less than 6.4 nM. To date, there is no published crystal structure complex any kinase. better understand the pan-FGFR selectivity LY2874455, we have determined kinase domain bound at a resolution 2.35 Å. type I inhibitor FGFR4, binds ATP-binding pocket...
FIIN-2, TAS-120 (Futibatinib) and PRN1371 are highly potent pan-FGFR covalent inhibitors targeting the p-loop cysteine of FGFR proteins, which currently in clinical trials. It is critical to analyze their target selectivity abilities overcome gatekeeper mutations. In this study, we demonstrate that FIIN-2 form adducts with SRC, while does not. inhibit SRC YES activities, Moreover, exhibit different potencies against mutants. addition, co-crystal structures SRC/FIIN-2, SRC/TAS-120...
Hydrogen-bonding organocatalysts L-pyroglutamic sulphonamides were readily synthesized for the first time by fully exploiting potentials of acid. The newly designed catalyst was successfully applied in catalyzing asymmetric Diels–Alder cyclization methyleneindolinones with 2-vinyl-1H-indoles to efficiently assemble carbazolespirooxindoles excellent stereoselectivity (up 99% ee, >20:1 dr) and yields 99%). Mechanistic studies disclosed that well-designed hydrogen-bonding modes between...
Fe2O3 nanoflakes were synthesized via a hydrothermal method and employed as cathode catalyst for non-aqueous Li-air batteries. The with an average diameter of ∼90 nm well crystallized. manifest superior catalytic activity oxygen reduction reaction evolution in discharge-recharge voltage gap Fe2O3/super P is reduced to ∼0.83 V. By the addition Fe2O3, cell exhibits capacity ∼5200 mAh/gelectrode, shows rate capability ∼2000 mAh/gelectrode at current density 0.4 mA/cm2, it also has stable...
The reversible pH-response of the Ag–PAAS catalyst allows it to catalyze selective hydration various nitriles quasi-homogeneously in water and be easily recovered by simply adjusting pH value solution.
A new approach to the synthesis of tetrasubstituted furans using aromatic alkynes catalyzed by PdCl<sub>2</sub> in DMA (<i>N</i>,<i>N</i>-dimethylacetamide)–H<sub>2</sub>O with dioxygen as sole oxidant is described, which oxygen atom furan was from water. The preliminary mechanistic understanding this transformation investigated.
Development of highly active and recyclable catalysts for selective hydrogenation nitroarenes to amines in water at room temperature is always a challenge chemical industry. This study reports facile situ method synthesis ultrafine palladium platinum nanoparticles (NPs) stabilized by poly (amic acid) salt (PAAS) their potential as with sodium borohydride or molecular hydrogen reductant temperature. In the reduction 4‐nitrophenol 4‐aminophenol borohydride, activity parameters PdNPs–PAAS...
An efficient method for the synthesis of benzo[ d ]thiazol-2-ylphosphonates via copper( ii )-catalyzed tandem bicyclization o -halophenyl isothiocyanates and organophosphorus esters.