Abstract Meat quality has an important genetic component and can be modified by the fatty acid (FA) composition amount of fat contained in adipose tissue muscle. The present study aimed to find genomic regions associated with FA backfat muscle ( longissimus dorsi ) 439 pigs three different backgrounds but having Iberian breed common. Genome-wide association studies (GWAS) were performed between 38,424 single-nucleotide polymorphisms (SNPs) covering pig genome 60 phenotypic traits related...

An experimental F2 cross between Iberian and Landrace pig strains was performed to map quantitative trait loci (QTL) for diverse productive traits. Here we report results meat quality traits from 369 animals with records pH 24 h postmortem (pH h), muscle color Minolta measurements L* (lightness), a* (redness), b* (yellowness), H* (hue angle), C* (chroma), intramuscular fat (IMF) haematin pigment content measured in the longissimus thoracis. Pigs were genotyped 92 markers covering 18 porcine...

The lipid content and fatty acid (FA) profile have an important impact in human health as well the technological transformation nutritional organoleptic quality of meat. A genome-wide association study (GWAS) on 144 backcross pigs (25% Iberian × 75% Landrace) was performed for 32 traits associated with intramuscular FA composition indices metabolism. GWAS carried out using Qxpak 5.0 genotyping information obtained from Porcine SNP60K BeadChip (Illumina Inc., San Diego, CA). Signals...

The ELOVL fatty acid elongase 6 (ELOVL6), the only related to de novo lipogenesis, catalyzes rate-limiting step in elongation cycle by controlling balance mammals. It is located on pig chromosome 8 (SSC8) a region where QTL affecting palmitic, and palmitoleic composition was previously detected, using an Iberian x Landrace intercross. main goal of this work fine-map evaluate ELOVL6 gene as positional candidate percentages palmitic acids pigs.The combination haplotype-based approach...

Fatty acids (FA) play a critical role in energy homeostasis and metabolic diseases; the context of livestock species, their profile also impacts on meat quality for healthy human consumption. Molecular pathways controlling lipid metabolism are highly interconnected not fully understood. Elucidating these molecular processes will aid technological development towards improvement pork increased knowledge FA metabolism, underpinning diseases humans. The results from genome-wide association...

Abstract The aim of this study was to investigate methods for detecting QTL in outbred commercial pig populations. Several back fat and growth rate, previously detected experimental resource populations, were examined segregation 10 different Two hundred trait-by-population-by-chromosome tests performed, resulting 20 being significant at the 5% level. In addition, 53 11 meat quality traits declared significant, using a subset These results show that considerable amount phenotypic variance...

The identification of QTL related to production traits that are relevant for the pig industry has been mostly performed by using divergent crosses. main objective current study was investigate whether these growth, fatness, and meat quality QTL, previously described in diverse experimental populations, were segregating a Landrace commercial population selected litter size, backfat thickness, growth performance. We have found carcass weight (posterior P > 0.75), cutlet 0.99), ham shoulders...

Results from a QTL experiment on growth and carcass traits in an experimental F2 cross between Iberian Landrace pigs are reported. Phenotypic data for growth, length of muscle mass, fat deposition composition 321 individuals corresponding to 58 families were recorded. Animals genotyped 92 markers covering the 18 porcine autosomes (SSC). The results genomic scan show genomewide significant SSC2 (longissimus area backfat thickness), SSC4 (length carcass, thickness, loin, shoulder belly bacon...

The primary goal of this study was to detect and confirm QTL on SSC6 for growth fatness traits in 2 experimental F(2) intercrosses: Iberian x Landrace (IB LR) Meishan MS), which were used the first time a analysis related productive traits. For purpose, single- joint-population analyses with single bivariate trait models both populations performed. presence backfat thickness previously identified IB LR cross detected population additional molecular information, but also confirmed MS cross....

This work presents an analysis of heterogeneity environmental variance for slaughter weight (175 days) in pigs. is associated with systematic and additive genetic effects. The model also postulates the presence effects affecting mean variance. study reveals variation at level variance, but absence correlation, or a small negative between both types In addition, we show that both, on those have important influence upon future economic performance selected individuals.

The fine mapping of polymorphisms influencing cholesterol (CT), triglyceride (TG), and lipoprotein serum levels in human mouse has provided a wealth knowledge about the complex genetic architecture these traits. extension analyses to pigs would be utmost importance since they constitute valuable biological clinical model for study coronary artery disease myocardial infarction. In present work, we performed whole genome scan lipid traits half-sib Duroc pig population 350 individuals....

Previous results from a genome scan in an F2 Iberian × Meishan pig intercross showed several chromosome regions associated with litter size traits this species. In order to identify candidate genes underlying these quantitative trait loci (QTL), we performed ovary gene expression analysis during the sow's pregnancy. sows were ranked by their estimated breeding values for prolificacy: six highest value (EBV) (i.e., high prolificacy) and lowest EBV (low selected. Samples hybridized using...

The aim of this study was to estimate the genetic and environmental parameters crossbreeding effects on fatty acid fat traits in Iberian pig. Our final goal is explore target selection define strategies. phenotypes were obtained under intensive management from 470 animals a diallelic experiment involving Retinto, Torbiscal, Entrepelado lines. data set composed backfat thickness at fourth rib (BFT), intramuscular (IMF) longissimus thoracis (LT), profile for IMF subcutaneous (SCF) traits. Data...

Abstract The adipogenic nature of the Iberian pig defines many quality attributes its fresh meat and dry-cured products. distinct varieties exhibit great variability in genetic parameters for fat deposition composition muscle. aim this work is to identify common genomic regions related fatty acid Retinto, Torbiscal, Entrepelado their reciprocal crosses through a diallelic experiment. In study, we performed GWAS using high density SNP array on 382 pigs with multimarker regression Bayes B...

A total of 66,620 records from the first six parities for number piglets born alive (NBA) 20,120 Landrace sows and 24,426 weight (WT) backfat thickness (BT) at 175 d age were analyzed to estimate genetic parameters. The pedigree consisted 47,186 individuals, including 392 sires 5,394 dams. Estimates based on marginal posterior distribution parameters obtained using Bayesian inference implemented via Gibbs sampling procedure with a Data Augmentation step. means standard deviation (PSD)...

Summary Inbreeding is a biological phenomenon of special relevance in domestic species which its influence has been typically associated with reductions animal fitness. Nevertheless, recent research suggests substantial founder-specific variability terms inbreeding depression on some productive traits, although this centred very reduced number founders. This focuses the modelling (FSID) effects from more general point view, characterizing expected distribution FSID sow longevity. Under...

Evidence is accumulating that intronic polymorphic cytosine-adenosine (CA) repeats may play a role in gene expression. In this work, we investigated whether CA short tandem repeat (STR) located at the first intron of pig insulin-like growth factor I (IGF-I) influences plasma IGF-I concentration pigs as well phenotypic variation and fatness traits. We measured levels one to four time points from 35 215 days age 340 performance-tested Landrace Duroc previously genotyped for STR. Data were...

Prolificacy is the most important trait influencing reproductive efficiency of pig production systems. The low heritability and sex-limited expression prolificacy have hindered to some extent improvement this through artificial selection. Moreover, relative contributions additive, dominant epistatic QTL genetic variance remain be defined. In work, we undertaken issue by performing one-dimensional bi-dimensional genome scans for number piglets born alive (NBA) total (TNB) in a three...

In commercial livestock populations, QTL detection methods often use existing half-sib family structures and ignore additional relationships within between families. We reanalyzed the data from a large confirmation experiment with 10 pig lines chromosome regions using identity-by-descent (IBD) scores variance component analyses. The IBD were obtained Monte Carlo Markov Chain method, as implemented in LOKI software, used to model putative mixed animal model. analyses revealed 61 at nominal 5%...

The IGF2-intron3-G3072A substitution has been recently described as the causal factor of imprinted QTL for fat deposition and muscle growth detected within porcine IGF2 region. objective this study was to investigate effect in a Large White outbred population an Iberian x Landrace F2 cross. results showed that significant effects on fatness, growth, shape traits with estimated expected direction. These agree those obtained cross, where is segregating only small family. In addition, scan...

Muscle histochemical characteristics are decisive determinants of meat quality. The relative percentage and diameters the different muscular fiber types influence crucial aspects such as color, tenderness, ultimate pH. Despite its relevance, however, information on muscle genetic architecture is scant, because characterization a laborious task. Here we report complete QTL scan traits in 160 animals from F(2) cross between Iberian Landrace pigs using 139 markers. We identified 20 genome...