- Cardiac Health and Mental Health
- Cardiovascular Health and Risk Factors
- Health Promotion and Cardiovascular Prevention
- Diabetes Management and Education
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Function and Risk Factors
- Obesity and Health Practices
- Lipoproteins and Cardiovascular Health
- Heart Failure Treatment and Management
- Primary Care and Health Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac, Anesthesia and Surgical Outcomes
- Mobile Health and mHealth Applications
- Medication Adherence and Compliance
- Gestational Diabetes Research and Management
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Smoking Behavior and Cessation
- School Health and Nursing Education
- Fatty Acid Research and Health
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Clinical practice guidelines implementation
- Cardiovascular Disease and Adiposity
- Physical Activity and Health
Ollscoil na Gaillimhe – University of Galway
2023
University Hospital Galway
2022-2023
Imperial College London
2007-2021
Croí
2020
Imperial College Healthcare NHS Trust
2009-2018
Royal Berkshire Hospital
2015
Children's Hospital of Wisconsin
2012-2014
British Association for Counselling and Psychotherapy
2013
Nebraska Department of Health and Human Services
2013
Medical College of Wisconsin
2012
Most people who begin statins abandon them, most commonly because of side effects.The purpose this study was to assess daily symptom scores on statin, placebo, and no treatment in participants had abandoned statins.Participants received 12 1-month medication bottles, 4 containing atorvastatin 20 mg, empty. We measured intensity for each using an app (scale 1-100). also the "nocebo" ratio: ratio symptoms induced by taking statin that placebo.A total 60 were randomized 49 completed 12-month...
Background : The objective of this retrospective study was to evaluate the safety enteral feeding in children receiving vasoactive agents (VAs). Methods Patients aged 1 month 18 years with a pediatric intensive care unit stay for ≥96 hours during 2007 and 2008 who received any VA (epinephrine, norepinephrine, vasopressin, milrinone, dopamine, dobutamine) were included categorized into fed nonfed groups. Their demographics, clinical characteristics, type dose VA, presence gastrointestinal...
Gestational diabetes mellitus (GDM) is a risk factor for the development of type 2 diabetes. Lifestyle intervention can prevent progression to in high populations. We designed randomised controlled trial (RCT) evaluate effectiveness an established lifestyle compared standard care delaying onset European women with recent GDM. Recruitment into RCT was more challenging than anticipated only 89 410 (22%) agreeing participate. This paper identifies factors that could enhance participation target...
Objective . To evaluate a 12-week group-based lifestyle intervention programme for women with prediabetes following gestational diabetes (GDM). Design A two-group, mixed methods randomized controlled trial in which 50 history of GDM and abnormal glucose tolerance postpartum were randomly assigned to (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>24</mml:mn></mml:math>) or wait control...
Background In contrast to systemic hypertension, the significance of arterial waves in pulmonary hypertension ( PH ) is not well understood. We hypothesized that wave energy and reflection are augmented behavior differs between patients with PAH chronic thromboembolic CTEPH ). Methods Results Right heart catheterization was performed using a pressure Doppler flow sensor–tipped catheter obtain simultaneous velocity measurements artery. Wave intensity analysis subsequently applied acquired...
Abstract Objective Digital cardiac rehabilitation (CR) has emerged as a promising alternative to in‐person CR. Understanding patients' experiences and perceptions can provide valuable insights into what makes these programmes successful identify opportunities for improvement. This study aimed explore of digital CR understand the factors that make successful. Design A qualitative approach was taken. Methods From March August 2022, we conducted semi‐structured interviews with patients who were...
Transcriptome analysis using microarray technology represents a powerful unbiased approach for delineating pathogenic mechanisms in disease. Here molecular of renal tubulointerstitial fibrosis (TIF) were probed by monitoring changes the transcriptome glomerular disease-dependent model TIF (adriamycin nephropathy) Affymetrix (mu74av2) coupled with sequential primary biological function-focused and secondary "baited"-global cluster gene expression profiles. Primary focused on mRNAs encoding...
The aim of this observational, descriptive study is to evaluate the impact an intensive, evidence-based preventive cardiology programme on medical and lifestyle risk factors in patients at high developing cardiovascular disease (CVD). Increased CVD their family members/partners were invited attend a 16-week consisting professional multidisciplinary intervention, with appropriate factor therapeutic management community setting. Smoking, dietary habits, physical activity levels, waist...
<h3>Objective</h3> To determine in patients with coronary heart disease (CHD) and people at high risk of developing cardiovascular (CVD) whether the Joint British Societies9 guidelines on CVD prevention (JBS2) are followed everyday clinical practice. <h3>Design</h3> A cross-sectional survey was undertaken medical records patient interviews examinations least 6 months after recruiting event or diagnosis using standardised instruments a central laboratory for measurement lipids glucose....
The age at diagnosis of pulmonary arterial hypertension (PAH) and the prevalence cardiovascular (CV) risk factors are increasing. We sought to determine whether response drug therapy was influenced by CV in PAH patients. studied consecutive incident patients (n = 146) between January 1, 2008, July 15, 2011. Patients were divided into two groups: PAH-No group included with no (obesity, systemic hypertension, type 2 diabetes mellitus, permanent atrial fibrillation, mitral and/or aortic valve...
Necrotising fasciitis (NF) is an infection of soft tissues that rarely affects the breast. It associated with a high risk mortality if diagnosed late. We present case primary necrotising left breast in 30-year-old woman no co-morbidities. The patient initially presented septic cellulitis and necrotic patches overlying her as well disproportionate pain. An early diagnosis NF was made, aided by LRINEC score (laboratory indicator for necrotizing fasciitis). combination this prompt treatment...
BackgroundDespite the benefits of cardiac rehabilitation, uptake and adherence remain suboptimal. With advent NHS Health Checks, primary prevention programmes have also been advocated, but little is known about rates. This study examined rates predictors amongst patients with cardiovascular disease (CVD) those at high multifactorial risk (HRI) attending an innovative programme integrating secondary prevention.
Use of appropriate cardioprotective medication is a cornerstone cardiovascular disease prevention, but less-than-optimal patient adherence common. Thus, strategies for improving are recommended to adopt multifaceted approach.The objective our study was test system comprising biodegradable, ingestible sensor direct measurement ingestion in group patients at elevated risk attending cardiac prevention and rehabilitation program.In this prospective intervention trial single 21 running from April...
Though historically confined to hospital settings, methicillin-resistant Staphylococcus aureus (MRSA) has received increasing attention in the wider community, particularly among athletes. A 2007–2008 investigation Nebraska concluded that MRSA skin infections were an emerging problem state’s student Statewide surveillance was subsequently conducted during 4 school years (2008–2012) estimate incidence of and soft tissue (SSTI) consistent with High athletic officials completed Internet-based...