A5025865070- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Viral Infections and Vectors
- Hepatitis B Virus Studies
- Animal Disease Management and Epidemiology
- Phytochemistry and Biological Activities
- Sirtuins and Resveratrol in Medicine
- Nanoparticles: synthesis and applications
- Allelopathy and phytotoxic interactions
- Phytochemical compounds biological activities
- Nanoparticle-Based Drug Delivery
- Plant-Derived Bioactive Compounds
- Nigella sativa pharmacological applications
- RNA Interference and Gene Delivery
- Curcumin's Biomedical Applications
- Natural product bioactivities and synthesis
- Natural Compounds in Disease Treatment
- Graphene and Nanomaterials Applications
- Psidium guajava Extracts and Applications
- Botanical Research and Applications
- Medicinal Plant Research
Iraqi University
2021-2024
October University of Modern Sciences and Arts
2018-2022
There is a huge demand for novel anticancer agents with fewer side effects compared to current therapies. Pitaya, or dragon fruit, reservoir of potent compounds. This research aimed analyze the phytochemical components Hylocereus undatus pulp and peel extracts using LC-MS GC-MS, investigate in vitro both against cancer (breast, MCF-7, colon, Caco-2) normal (lung; WI-38 breast; MCF-10A) cell proliferation MTT assay. The apoptosis potential was also evaluated flow cytometry, RT-PCR, Western...
Resveratrol (RSV), a non-flavonoid stilbene polyphenol, possesses anti-carcinogenic activities against all the major stages of cancer. Zein nanoparticles (ZN NPs) have been utilized successfully in delivery variant therapeuticals by virtue their histocompatible nature. The goal this work was to comparatively explore antiproliferative, pro-apoptotic and oxidative stress potentials RSV-ZN NPs versus RSV human colorectal carcinoma HCT-116 cells. ZN-RSV were developed assayed for particle size...
Pimenta racemosa tree has many traditional uses where its leaves are used as herbal tea for treatment of flatulence, gastric disorder, osteoarthritis, colds and fever in addition to analgesic anti-inflammatory activities. So, this study aimed isolate phenolic constituents 80% aqueous methanol extract (AME) evaluate biological The defatted AME was chromatographed structures the isolated compounds were elucidated using UV, NMR spectroscopy UPLC-ESI-MS analysis. Antioxidant activity...
Aim: The antiviral potentials of rosmarinic acid (RA) against Rift Valley fever (RVF) virus were investigated. Methods: Antiviral activity was investigated by evaluating the reduction in viral infectivity titer. Computational and LC–MS studies performed for investigating mechanism action. This is via testing interaction between RA its major metabolite with key proteins determination cellular permeability. Results: A superior RVF titer (45.5%) observed when applied post-infection compared to...
Abstract Methotrexate (MTX) is commonly employed in cancer treatment, but its clinical use restricted due to the MTX‐associated renal injury. This study investigates combined potential of Rhus coriaria (sumac) and bone marrow mesenchymal stem cells (BMMSCs) against MTX‐induced nephrotoxicity rats. The high‐resolution‐liquid chromatography‐mass spectrometry (HR‐LC‐MS) sumac extract tentatively identified 22 phytochemicals, mostly flavonoids, anthocyanins, steroids. Preparation liposomes...
The hydro distilled essential oil obtained from Calothamnus quadrifidus leaves was analyzed by gas liquid chromatography-mass spectroscopy. Quantification of the constituents carried out using chromatography-flame ionization detection device where 1,8-cineole quantified as 525.62 μg/ml. showed potential antioxidant activity when tested 1,1-diphenyl-2-picrylhydrazine radical scavenging assay concentration required to scavenge 50 %=37.3 μg. cytotoxic evaluated 3-(4,5-dimethylthiazol-...