A5052285815- Plant Stress Responses and Tolerance
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Plant-Microbe Interactions and Immunity
- RNA and protein synthesis mechanisms
- Plant Parasitism and Resistance
- RNA Research and Splicing
- Plant responses to water stress
- Ubiquitin and proteasome pathways
- Endoplasmic Reticulum Stress and Disease
- Neurobiology and Insect Physiology Research
- Plant nutrient uptake and metabolism
- Genomics and Phylogenetic Studies
- Bioinformatics and Genomic Networks
- Light effects on plants
- Fungal and yeast genetics research
- Seed Germination and Physiology
- Nuts composition and effects
- Plant Genetic and Mutation Studies
- Horticultural and Viticultural Research
- Plant and Fungal Interactions Research
- Retinoids in leukemia and cellular processes
- Plant Virus Research Studies
- Chromatin Remodeling and Cancer
- Calcium signaling and nucleotide metabolism
Duksung Women's University
2012-2024
Sungkyunkwan University
2019
University of California, San Diego
2007-2012
Consejo Superior de Investigaciones Científicas
2009
Universitat Politècnica de València
2009
Instituto de Biología Molecular y Celular de Plantas
2009
University of Tennessee at Knoxville
2000-2007
Abstract The phytohormone abscisic acid (ABA) is a key regulator of plant growth and development as well responses to situations decreased water availability. Protein phosphatases type 2C (PP2Cs) from group A, which includes the ABI1/HAB1 PP2CA branches, are negative regulators ABA signaling. Specifically, HAB1, ABI1, ABI2, have been shown affect both seed vegetative ABA. To further understand their contribution signaling unravel possible genetic interactions functional redundancy among...
The signal transduction pathway governed by the phytohormone abscisic acid (ABA) regulates not only abiotic stress responses but also early developmental programs such as seed dormancy, germination and seedling growth in response to environmental signals. Optimal plant development depend on integration of stimuli intrinsic programs. Here, we show that homeodomain transcription factors BLH1 KNAT3, previously implicated embryo sac development, have additional functions ABA-mediated dormancy...
Eukaryotic translation initiation factor 3 (eIF3) consists of core subunits that are conserved from yeast to man as well less conserved, noncore, with potential regulatory roles. Whereas tend be indispensable for cell growth, the roles noncore remain poorly understood. We addressed hypothesis eIF3 have accessory functions help regulate initiation, by focusing on Arabidopsis thaliana eIF3h subunit. Indeed, was not essential general protein translation. However, results transient expression...
Abstract In a chemical genetics screen we identified the small-molecule [5-(3,4-dichlorophenyl)furan-2-yl]-piperidine-1-ylmethanethione (DFPM) that triggers rapid inhibition of early abscisic acid signal transduction via PHYTOALEXIN DEFICIENT4 (PAD4)- and ENHANCED DISEASE SUSCEPTIBILITY1 (EDS1)-dependent immune signaling mechanisms. However, mechanisms upstream EDS1 PAD4 in DFPM-mediated remain unknown. Here, report DFPM generates an Arabidopsis thaliana accession-specific root growth arrest...
The <i>Arabidopsis</i> COP9 signalosome is a multisubunit repressor of photomorphogenesis that conserved among eukaryotes. This complex may have general role in development. As step dissecting the biochemical mode action signalosome, we determined sequence proteins copurify with this complex. Here describe association between components (CSN1, CSN7, and CSN8) two subunits eukaryotic translation initiation factor 3 (eIF3), eIF3e (p48, known also as INT-6) eIF3c (p105). To obtain marker for...
A forward-genetic screen in Arabidopsis led to the isolation of several arsenic tolerance mutants. ars5 was strongest arsenate- and arsenite-resistant mutant identified this genetic screen. Here, we report characterization cloning gene. is shown exhibit an increased accumulation thiol compounds during stress. Rough mapping together with microarray-based expression mutation alpha subunit F (PAF1) 26S proteasome complex. Characterization independent paf1 T-DNA insertion allele complementation...
Plants have evolutionarily established resistance responses to a variety of abiotic stress conditions, in which ABA mediates the integrated regulation these responses. Numerous proteins function at transcription level or protein when contributing controls signaling process. Although osmotin is identified as salt-inducible protein, its response yet be elucidated. To examine role Arabidopsis OSMOTIN 34 (OSM34) pathway, deletion mutant osm34 generated by CRISPR/Cas9 system and double osml...
Abstract The Arabidopsis COP1 protein functions as a developmental regulator, in part by repressing photomorphogenesis darkness. Using complementation of cop1 loss-of-function allele with transgenes expressing fusions mutant proteins and β-glucuronidase, it was confirmed that consists two modules, an amino terminal module conferring basal function during development carboxyl repression photomorphogenesis. amino-terminal zinc-binding domain indispensable for function. In contrast, the...
Summary The roles of individual eukaryotic translation initiation factor 3 (eIF3) subunits are largely unclear, although some essential, while others thought to have regulatory roles. ‘e’ subunit, also known as Int‐6/Int6, is a candidate for subunit it not essential in yeasts. eIF3e associates with the COP9 signalosome, and localizes nucleus certain tissues. To further elucidate eIF3e, we taken genetic approach using Arabidopsis model system. Overexpression results defects similar mutations...
Insight into how plants simultaneously cope with multiple stresses, for example, when challenged biotic stress from pathogen infection and abiotic drought, is important both understanding evolutionary trade-offs optimizing crop responses to these stresses. Mechanisms by which initial plant immune signaling antagonizes abscisic acid (ABA) signal transduction require further investigation. Using a chemical genetics approach, the small molecule...
Abiotic stresses, such as drought, salinity, and extreme temperatures, limit plant growth development, reducing crop yields. Therefore, a more comprehensive understanding of the signaling mechanisms responses plants to changing environmental conditions is crucial for improving sustainable agricultural productivity. Chemical screening was conducted find novel small compounds that act regulators abiotic stress pathway using ABA-inducible transgenic reporter line. Small molecules called...
마이크로어레이 유전자 발현 데이터인 yeast cdc15에 대해 시계열 데이터의 특성을 반영한 푸리에 계수를 이용한 검정통계량과 FDR 다중비교법을 이용하여 차별화된 유전자를 선별한 후 선별된 유전자들에 모형기반 군집방법, K-평균법, PAM, SOM, 계층적 Ward 군집방법과 Fuzzy 군집방법을 실시하였다. 군집방법에 따른 알아보고 군집화 결과와 내부유효성 측도로 연결성 측도, Dunn 지수와 실루엣 값을 살펴본다. 또한 GO분석을 통한 생물학적 의미도 파악해본다. We accomplish clustering analyses for cell cycle microarray expression data. To reflect the characteristics of a time-course data, we screen genes using test statistics with Fourier coefficients applying procedure. compare results...