A5001542437- Enzyme Structure and Function
- Ubiquitin and proteasome pathways
- Agriculture, Soil, Plant Science
- Monoclonal and Polyclonal Antibodies Research
- Cellular transport and secretion
- Advanced biosensing and bioanalysis techniques
- Glycosylation and Glycoproteins Research
- RNA and protein synthesis mechanisms
- Food Quality and Safety Studies
- Cancer-related Molecular Pathways
- Plant Stress Responses and Tolerance
- DNA and Nucleic Acid Chemistry
- Pneumonia and Respiratory Infections
- Biosensors and Analytical Detection
- Membrane-based Ion Separation Techniques
- Laser Applications in Dentistry and Medicine
- Microfluidic and Capillary Electrophoresis Applications
- Microfluidic and Bio-sensing Technologies
- Genomics and Phylogenetic Studies
- Advanced Biosensing Techniques and Applications
- Olfactory and Sensory Function Studies
- Nutrition, Health and Food Behavior
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Galectins and Cancer Biology
Sungkyunkwan University
2016-2025
Daegu Gyeongbuk Institute of Science and Technology
2024
Institute for Basic Science
1999-2024
Institute of Science and Technology
2024
Naval Medical Research Command
2024
Jeju National University
2022-2023
Areté Associates (United States)
2023
CHA Bundang Medical Center
2023
Instituto de Ciencias Agrarias
2023
Kyung Hee University Hospital at Gangdong
2016-2022
We report an electrochemical method for the sequence-specific detection of unpurified amplification products gyrB gene Salmonella typhimurium. Using asymmetric PCR and E-DNA scheme, single-stranded amplicons were produced from as few 90 copies and, without subsequent purification, rapidly identified. The is specific; sensor does not respond when challenged with control oligonucleotides based on genes either Escherichia coli or various Shigella species. In contrast to existing optical-...
This study demonstrates a simple approach for fabricating 3D-μPAD from single sheet of paper by double-sided printing and lamination.
Abstract Extracellular vesicles (EVs) are essential mediators in intercellular communication that have emerged as natural therapeutic nanomedicines for the treatment of intractable diseases. Their applications, however, been limited by unpredictable vivo biodistribution after systemic administration. To control fate EVs, their surfaces should be properly edited, depending on target site action. Herein, based bioorthogonal copper‐free click chemistry (BCC), surface‐edited EVs were prepared...
In intelligent vehicles, it is essential to monitor the driver’s condition; however, recognizing emotional state one of most challenging and important tasks. Most previous studies focused on facial expression recognition state. However, while driving, many factors are preventing drivers from revealing emotions their faces. To address this problem, we propose a deep learning-based real emotion recognizer (DRER), which algorithm recognize drivers’ that cannot be completely identified based...
Oxidative stress and inflammation are implicated in the pathogenesis of diabetic nephropathy. Because sildenafil citrate (Viagra) has variable cardiovascular benefits, including antioxidative immunomodulating effects, we investigated its influence on oxidative rat kidney.Streptozotocin-induced rats received (3 mg/kg/day drinking water) or not (undosed for 8 weeks were compared to age-matched nondiabetic animals. We evaluated 8-hydroxydeoxyguanosine (8-OHdG; DNA damage), inducible nitric...
The conformational changes of whey proteins upon adsorption at the soy oil/water interface were investigated using Fourier transform infrared (FT-IR) spectroscopy. Significant observed in bands assigned to beta-sheets and alpha-helix structures following interface. remaining interfacial after Tween 20 desorption revealed small beta-sheet alpha-helical structures, whereas desorbed unordered largely increased, almost disappeared. These FT-IR results provide important knowledge about...
Successful delivery of sperm cells to the embryo sac in higher plants is mediated by pollen tube growth. The molecular mechanisms underlying germination and growth crop remain rather unclear, although these are crucial plant reproduction seed formation. By screening pollen-specific gene mutants rice (Oryza sativa), we identified a T-DNA insertional mutant Germinating modulator (GORI) that showed one-to-one segregation ratio for wild type (WT) heterozygous. GORI encodes seven-WD40-motif...
Abstract Heterodimeric Fc designed by engineering the CH3 homodimeric interface of immunoglobulin G1 serves as an attractive scaffold for generation bispecific antibodies (bsAb) due to favorable properties region. In this study, we describe a heterodimeric generated substituting conserved electrostatic interactions at core with asymmetric hydrophobic and introducing asymmetric, long-range rim interface. Coexpression proteins carrying combined variant pairs in HEK293F cells produced...
Double-stranded ribonucleic acid-activated protein kinase (PKR) downregulates translation as a defense mechanism against viral infection. In fish species, PKZ, PKR-like containing left-handed deoxyribonucleic acid (Z-DNA) binding domains, performs similar role in the antiviral response. To understand of PKZ Z-DNA recognition and innate immune response, we performed structural functional studies domain (Zα) from Carassius auratus (caZαPKZ). The 1.7-Å resolution crystal structure caZαPKZ:Z-DNA...
The core ABA signaling components functioning in stomatal closure/opening, namely receptors, phosphatases, SnRK2s and SLAC1, are well characterized Arabidopsis, but their functions guard cells of rice have not been extensively studied. In this study, we confirmed that OsSLAC1, the homolog AtSLAC1, is specifically expressed cells. Among SAPKs, SAPK10 was addition, phosphorylated OsSLAC1 vitro transgenic overexpressing or showed significantly less water loss than control. Thus, those might be...
Although activin receptor IIB (ACVR2B) is emerging as a novel pathogenic receptor, its ligand and assembled components (or assembly) are totally unknown in the context of osteoarthritis (OA) pathogenesis. The present results suggest that upregulation ACVR2B assembly could affect osteoarthritic cartilage destruction. It shown ligand, A, regulates catabolic factor expression through OA development. Activin A Tg mice (Col2a1-Inhba) exhibit enhanced destruction, whereas heterozygous KO (Inhba+/-...