- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Traditional Chinese Medicine Studies
- Immune Cell Function and Interaction
- Sirtuins and Resveratrol in Medicine
- Traditional Chinese Medicine Analysis
- Chemokine receptors and signaling
- Cancer-related molecular mechanisms research
- Cancer Mechanisms and Therapy
People's Liberation Army 401 Hospital
2021
Tumor Hospital of Guangxi Medical University
2019
Shanghai University of Traditional Chinese Medicine
2007-2016
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2007-2016
In traditional Chinese medicine (TCM) clinical practice, ZHENG (also known as TCM syndrome) helps to understand the human homeostasis and guide individualized treatment. However, scientific basis of remains unclear due limitations current reductionist approaches. We collected leukocyte samples three hepatitis B-caused cirrhosis (HBC) patients with dampness-heat accumulation syndrome (DHAS) HBC liver depression spleen deficiency (LDSDS) for microarray analysis. generated...
Liver cirrhosis is one of the most common non-neoplastic causes mortality worldwide. Chronic hepatitis B (CHB) a major cause liver in China. To find biomarkers for diagnosis CHB caused (HBC), we examined transcriptional profiling and HBC. The leukocyte samples (n = 5) HBC were analyzed by microarray. results showed that 2128 mapped genes differentially expressed between (fold change ≥ 2.0, p < 0.05). Gene ontology (GO) analysis indicated these (DEGs) enriched immune response cell formation...
Astragaloside IV (AS-IV) has been shown to possess cardioprotective effect. However, the specific mechanism of AS-IV in myocardial infarction (MI) remains unclear. Our results showed that intervention observably enhanced cell viability and reduced apoptosis, oxidative stress levels inflammatory factor secretion. Expression MIRT1 was significantly up-regulated hypoxia-treated cells. In addition, ALCAM overexpression reversed effects on functions. facilitated Runx3 promoter methylation its...