Alexander Zwirzitz

ORCID: 0000-0002-0703-0005
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About
Contact & Profiles
Research Areas
  • Protease and Inhibitor Mechanisms
  • Biofuel production and bioconversion
  • Glycosylation and Glycoproteins Research
  • Microbial Metabolic Engineering and Bioproduction
  • Cellular transport and secretion
  • Cell Image Analysis Techniques
  • Polysaccharides and Plant Cell Walls
  • Protein Hydrolysis and Bioactive Peptides
  • Signaling Pathways in Disease
  • Advanced Fluorescence Microscopy Techniques
  • Enzyme Catalysis and Immobilization
  • Monoclonal and Polyclonal Antibodies Research
  • biodegradable polymer synthesis and properties
  • Advanced Biosensing Techniques and Applications
  • Microplastics and Plastic Pollution
  • Enzyme Production and Characterization
  • Peptidase Inhibition and Analysis
  • Catalysis for Biomass Conversion
  • Plant nutrient uptake and metabolism
  • Infant Nutrition and Health
  • Calcium signaling and nucleotide metabolism
  • Blood Coagulation and Thrombosis Mechanisms
  • Nanoparticle-Based Drug Delivery

University of Applied Sciences Upper Austria
2020-2024

Medical University of Vienna
2012-2018

The plasminogen system is essential for dissolution of fibrin clots, and in addition, it involved a wide variety other physiological processes, including proteolytic activation growth factors, cell migration, removal protein aggregates. On the hand, uncontrolled contributes to many pathological processes (e.g. tumor cells' invasion cancer progression). Moreover, some virulent bacterial species Streptococci or Borrelia) bind human hijack host's penetrate tissue barriers. Thus, conversion...

10.1074/jbc.ra118.003145 article EN cc-by Journal of Biological Chemistry 2018-04-18

Meyerozyma guilliermondii, a non-conventional yeast that naturally assimilates xylose, is considered as candidate for biotechnological production of the sugar alternative xylitol. Because genes xylose metabolism were yet unknown, all efforts published so far to increase xylitol yield this are limited fermentation optimization. Hence, study aimed genetically engineer organism first time with objective production. Therefore, previously uncharacterized M. guilliermondii ATCC 6260 encoding...

10.1186/s13568-020-01012-8 article EN cc-by AMB Express 2020-04-20

Abstract Using lignocellulosic raw materials as substrate for biotechnological applications has been a focus of research during the last two decades. They contain sugars, which can be used in industrial fermentation processes, from polysaccharides (cellulose, hemicellulose). Wheat straw, one representative materials, is sustainably and abundantly available, especially Europe North America. However, wheat just like any other material, needs to pretreated way or order generate sufficient...

10.1007/s13399-020-01266-z article EN cc-by Biomass Conversion and Biorefinery 2021-01-12

The spatial and temporal organization of T cell signaling molecules is increasingly accepted as a crucial step in controlling activation. CD222, also known the cation-independent mannose 6-phosphate/insulin-like growth factor 2 receptor, central component endosomal transport pathways. In this study, we show that CD222 key regulator early cascade. Knockdown hampers effective progression TCR-induced subsequent effector functions, which can be rescued via reconstitution expression. We decipher...

10.4049/jimmunol.1303349 article EN The Journal of Immunology 2014-08-16

The interest in using non-conventional yeasts to produce value-added compounds from low cost substrates, such as lignocellulosic materials, has increased recent years. Setting out discover novel microbial strains that can be used biorefineries, an Issatchenkia orientalis strain was isolated waste cooking oil (WCO) and its capability ethanol wheat straw hydrolysate (WSHL) analyzed. As with previously I. strains, WCO-isolated KJ27-7 is thermotolerant. It grows well at elevated temperatures up...

10.3390/jof7020121 article EN cc-by Journal of Fungi 2021-02-06

The association of lipid rafts with nuclei during partial cell lysis enables their analysis by flow cytometry.

10.1126/scisignal.aac5584 article EN Science Signaling 2015-09-22
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